PMID- 30776994
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20191125
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 50
IP  - 3
DP  - 2019 Mar
TI  - Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the 
      STRATIS Stroke Thrombectomy Registry.
PG  - 697-704
LID - 10.1161/STROKEAHA.118.021126 [doi]
AB  - Background and Purpose- Mechanical thrombectomy has been shown to improve clinical 
      outcomes in patients with acute ischemic stroke. However, the impact of balloon 
      guide catheter (BGC) use is not well established. Methods- STRATIS (Systematic 
      Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic 
      Stroke) was a prospective, multicenter study of patients with large vessel occlusion 
      treated with the Solitaire stent retriever as first-line therapy. In this study, an 
      independent core laboratory, blinded to the clinical outcomes, reviewed all 
      procedures and angiographic data to classify procedural technique, target clot 
      location, recanalization after each pass, and determine the number of stent 
      retriever passes. The primary clinical end point was functional independence 
      (modified Rankin Scale, 0-2) at 3 months as determined on-site, and the angiographic 
      end point was first-pass effect (FPE) success rate from a single device attempt 
      (modified Thrombolysis in Cerebral Infarction, ≥2c) as determined by a core 
      laboratory. Achieving modified FPE (modified Thrombolysis in Cerebral Infarction, 
      ≥2b) was also assessed. Comparisons of clinical outcomes were made between groups 
      and adjusted for baseline and procedural characteristics. All participating centers 
      received institutional review board approval from their respective institutions. 
      Results- Adjunctive technique groups included BGC (n=445), distal access catheter 
      (n=238), and conventional guide catheter (n=62). The BGC group had a higher rate of 
      FPE following first pass (212/443 [48%]) versus conventional guide catheter (16/62 
      [26%]; P=0.001) and distal access catheter (83/235 [35%]; P=0.002). Similarly, the 
      BGC group had a higher rate of modified FPE (294/443 [66%]) versus conventional 
      guide catheter (26/62 [42%]; P<0.001) and distal access catheter (129/234 [55%]; 
      P=0.003). The BGC group achieved the highest rate of functional independence 
      (253/415 [61%]) versus conventional guide catheter (23/55 [42%]; P=0.007) and distal 
      access catheter (113/218 [52%]; P=0.027). Final revascularization and mortality 
      rates did not differ across the groups. Conclusions- BGC use was an independent 
      predictor of FPE, modified FPE, and functional independence, suggesting that its 
      routine use may improve the rates of early revascularization success and good 
      clinical outcomes. Clinical Trial Registration- URL: https://www.clinicaltrials.gov 
      . Unique identifier: NCT02239640.
FAU - Zaidat, Osama O
AU  - Zaidat OO
AD  - From the Mercy Health St. Vincent Mercy Hospital, Toledo, OH (O.O.Z.).
FAU - Mueller-Kronast, Nils H
AU  - Mueller-Kronast NH
AD  - Advanced Neuroscience Network/Tenet South Florida, Coral Springs (N.H.M.-K., R.K.).
FAU - Hassan, Ameer E
AU  - Hassan AE
AD  - Valley Baptist Medical Center, Harlingen, TX (A.E.H.).
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Emory University School of Medicine, Atlanta, GA (D.C.H.).
AD  - Grady Memorial Hospital, Atlanta, GA (D.C.H., R.G.N.).
FAU - Jadhav, Ashutosh P
AU  - Jadhav AP
AD  - University of Pittsburgh Medical Center, PA (A.P.J.).
FAU - Froehler, Michael T
AU  - Froehler MT
AD  - Vanderbilt University Medical Center, Nashville, TN (M.T.F., R.C.).
FAU - Jahan, Reza
AU  - Jahan R
AD  - University of California, Los Angeles, CA (R.J., J.L.S., S.S., D.S.L.).
FAU - Ali Aziz-Sultan, Mohammad
AU  - Ali Aziz-Sultan M
AD  - Brigham and Women's Hospital, Boston, MA (M.A.A-S.).
FAU - Klucznik, Richard P
AU  - Klucznik RP
AD  - Methodist Hospital, Houston, TX (R.P.K.).
FAU - Saver, Jeffrey L
AU  - Saver JL
AD  - University of California, Los Angeles, CA (R.J., J.L.S., S.S., D.S.L.).
FAU - Hellinger, Frank R Jr
AU  - Hellinger FR Jr
AD  - Florida Hospital Neuroscience Institute, Winter Park (F.R.H., R.H.G.).
FAU - Yavagal, Dileep R
AU  - Yavagal DR
AD  - University of Miami Miller School of Medicine/Jackson Memorial Hospital, FL (D.R.Y., 
      E.C.P.).
FAU - Yao, Tom L
AU  - Yao TL
AD  - Norton Neuroscience Institute, Norton Healthcare, Louisville, KY (T.L.Y., S.D.).
FAU - Gupta, Rishi
AU  - Gupta R
AD  - WellStar Neurosciences Network, WellStar Kennestone Regional Medical Center, 
      Marietta, GA (R.G.).
FAU - Martin, Coleman O
AU  - Martin CO
AD  - St. Luke's Hospital of Kansas City, MO (C.O.M.).
FAU - Bozorgchami, Hormozd
AU  - Bozorgchami H
AD  - Oregon Health and Science University Hospital, Portland (H.B.).
FAU - Kaushal, Ritesh
AU  - Kaushal R
AD  - Advanced Neuroscience Network/Tenet South Florida, Coral Springs (N.H.M.-K., R.K.).
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Grady Memorial Hospital, Atlanta, GA (D.C.H., R.G.N.).
FAU - Gandhi, Ravi H
AU  - Gandhi RH
AD  - Florida Hospital Neuroscience Institute, Winter Park (F.R.H., R.H.G.).
FAU - Peterson, Eric C
AU  - Peterson EC
AD  - University of Miami Miller School of Medicine/Jackson Memorial Hospital, FL (D.R.Y., 
      E.C.P.).
FAU - Dashti, Shervin
AU  - Dashti S
AD  - Norton Neuroscience Institute, Norton Healthcare, Louisville, KY (T.L.Y., S.D.).
FAU - Given, Curtis A 2nd
AU  - Given CA 2nd
AD  - Baptist Health Lexington/Central Baptist, KY (C.A.G.).
FAU - Mehta, Brijesh P
AU  - Mehta BP
AD  - South Broward Hospital, Hollywood, FL (B.P.M.).
FAU - Deshmukh, Vivek
AU  - Deshmukh V
AD  - Providence St. Vincent Medical Center, Portland, OR (V.D.).
FAU - Starkman, Sidney
AU  - Starkman S
AD  - University of California, Los Angeles, CA (R.J., J.L.S., S.S., D.S.L.).
FAU - Linfante, Italo
AU  - Linfante I
AD  - Baptist Hospital of Miami, FL (I.L.).
FAU - McPherson, Scott H
AU  - McPherson SH
AD  - St. Dominic's-Jackson Memorial Hospital, MS (S.H.M.).
FAU - Kvamme, Peter
AU  - Kvamme P
AD  - University of Tennessee Medical Center, Knoxville (P.K.).
FAU - Grobelny, Thomas J
AU  - Grobelny TJ
AD  - Advocate Christ Medical Center, Oak Lawn, IL (T.J.G.).
FAU - Hussain, Muhammad Shazam
AU  - Hussain MS
AD  - Cleveland Clinic, OH (M.S.H.).
FAU - Thacker, Ike
AU  - Thacker I
AD  - Baylor University Medical Center, Dallas, TX (I.T.).
FAU - Vora, Nirav
AU  - Vora N
AD  - OhioHealth Riverside Methodist Hospital, Columbus (N.V.).
FAU - Chen, Peng Roc
AU  - Chen PR
AD  - Memorial Hermann Texas Medical Center, Houston (P.R.C.).
FAU - Monteith, Stephen J
AU  - Monteith SJ
AD  - Swedish Medical Center First Hill Campus, Seattle, WA (S.J.M.).
FAU - Ecker, Robert D
AU  - Ecker RD
AD  - Maine Medical Center, Portland, ME (R.D.E.).
FAU - Schirmer, Clemens M
AU  - Schirmer CM
AD  - Geisinger Clinic, Danville, PA (C.M.S.).
FAU - Sauvageau, Eric
AU  - Sauvageau E
AD  - Baptist Medical Center Jacksonville, FL (E.S.).
FAU - Chebl, Alex Bou
AU  - Chebl AB
AD  - Baptist Hospital Louisville, KY (A.B.C.).
FAU - Derdeyn, Colin P
AU  - Derdeyn CP
AD  - Barnes Jewish Hospital, St. Louis, MO (C.P.D.).
FAU - Maidan, Lucian
AU  - Maidan L
AD  - Mercy San Juan Medical Center and Mercy General, Carmichael, CA (L.M.).
FAU - Badruddin, Aamir
AU  - Badruddin A
AD  - Presence St. Joseph Medical Center, Joliet, IL (A.B.).
FAU - Siddiqui, Adnan H
AU  - Siddiqui AH
AD  - Buffalo General Medical Center, NY (A.H.S.).
FAU - Dumont, Travis M
AU  - Dumont TM
AD  - University of Arizona Medical Center, Tucson (T.M.D.).
FAU - Alhajeri, Abdulnasser
AU  - Alhajeri A
AD  - University of Kentucky Hospital, Lexington (A.A.).
FAU - Taqi, Muhammad A
AU  - Taqi MA
AD  - Los Robles Medical Center, Thousand Oaks, CA (M.A.T.).
FAU - Asi, Khaled
AU  - Asi K
AD  - Aurora Hospital, Milwaukee, WI (K.A.).
FAU - Carpenter, Jeffrey
AU  - Carpenter J
AD  - West Virginia University/Ruby Memorial Hospital, Morgantown (J.C.).
FAU - Boulos, Alan
AU  - Boulos A
AD  - Albany Medical Center, NY (A.B.).
FAU - Jindal, Gaurav
AU  - Jindal G
AD  - University of Maryland Medical Center, Baltimore (G.J.).
FAU - Puri, Ajit S
AU  - Puri AS
AD  - University of Massachusetts Memorial Medical Center, Worcester (A.S.P.).
FAU - Chitale, Rohan
AU  - Chitale R
AD  - Vanderbilt University Medical Center, Nashville, TN (M.T.F., R.C.).
FAU - Deshaies, Eric M
AU  - Deshaies EM
AD  - Crouse Hospital, Syracuse, NY (E.M.D.).
FAU - Robinson, David
AU  - Robinson D
AD  - Virginia Mason Medical Center, Seattle, WA (D.R.).
FAU - Kallmes, David F
AU  - Kallmes DF
AD  - Mayo Clinic, Rochester, MN (D.F.K.).
FAU - Baxter, Blaise W
AU  - Baxter BW
AD  - Erlanger Medical Center, Chattanooga, TN (B.W.B.).
FAU - Jumaa, Mouhammed
AU  - Jumaa M
AD  - ProMedica Toledo Hospital, OH (M.J.).
FAU - Sunenshine, Peter
AU  - Sunenshine P
AD  - Banner University Medical Center, Phoenix, AZ (P.S.).
FAU - Majjhoo, Aniel
AU  - Majjhoo A
AD  - McLaren Flint, MI (A.M.).
FAU - English, Joey D
AU  - English JD
AD  - California Pacific Medical Center, San Francisco (J.D.E.).
FAU - Suzuki, Shuichi
AU  - Suzuki S
AD  - University of California, Irvine (S.S.).
FAU - Fessler, Richard D
AU  - Fessler RD
AD  - St. John Providence Hospital, Detroit, MI (R.D.F.).
FAU - Delgado-Almandoz, Josser
AU  - Delgado-Almandoz J
AD  - Abbott Northwestern Hospital, Minneapolis, MN (J.D-A.).
FAU - Martin, Jerry C
AU  - Martin JC
AD  - and Carolinas Medical Center, Charlotte, NC (J.C.M.).
FAU - Liebeskind, David S
AU  - Liebeskind DS
AD  - University of California, Los Angeles, CA (R.J., J.L.S., S.S., D.S.L.).
CN  - STRATIS Investigators
LA  - eng
SI  - ClinicalTrials.gov/NCT02239640
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Ischemia/diagnostic imaging/therapy
MH  - Catheterization/*methods
MH  - Cerebral Angiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Registries
MH  - Stents
MH  - Stroke/*diagnostic imaging/*surgery
MH  - Thrombectomy/*statistics & numerical data
MH  - Treatment Outcome
OTO - NOTNLM
OT  - *animals
OT  - *brain ischemia
OT  - *humans
OT  - *stroke
OT  - *thrombectomy
EDAT- 2019/02/20 06:00
MHDA- 2019/11/26 06:00
CRDT- 2019/02/20 06:00
PHST- 2019/02/20 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
PHST- 2019/02/20 06:00 [entrez]
AID - 10.1161/STROKEAHA.118.021126 [doi]
PST - ppublish
SO  - Stroke. 2019 Mar;50(3):697-704. doi: 10.1161/STROKEAHA.118.021126.

PMID- 28754806
OWN - NLM
STAT- MEDLINE
DCOM- 20180731
LR  - 20181202
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 10
IP  - 4
DP  - 2018 Apr
TI  - Impact of balloon guide catheter on technical and clinical outcomes: a systematic 
      review and meta-analysis.
PG  - 335-339
LID - 10.1136/neurintsurg-2017-013179 [doi]
AB  - BACKGROUND AND PURPOSE: Flow arrest with balloon guide catheters (BGCs) is becoming 
      increasingly recognized as critical to optimizing patient outcomes for mechanical 
      thrombectomy. We performed a systematic review and meta-analysis of the literature 
      for studies that compared angiographic and clinical outcomes for patients who 
      underwent mechanical thrombectomy with and without BGCs. MATERIALS AND METHODS: In 
      April 2017 a literature search on BGC and mechanical thrombectomy for stroke was 
      performed. All studies included patients treated with and without BGCs using modern 
      techniques (ie, stent retrievers). Using random effects meta-analysis, we evaluated 
      the following outcomes: first-pass recanalization, Thrombolysis In Cerebral 
      Infarction (TICI) 3 recanalization, TICI 2b/3 recanalization, favorable outcome 
      (modified Rankin Scale (mRS) 0-2), mortality, and mean number of passes and 
      procedure time. RESULTS: Five non-randomized studies of 2022 patients were included 
      (1083 BGC group and 939 non-BGC group). Compared with the non-BGC group, patients 
      treated with BGCs had higher odds of first-pass recanalization (OR 2.05, 95% CI 1.65 
      to 2.55), TICI 3 (OR 2.13, 95% CI 1.43 to 3.17), TICI 2b/3 (OR 1.54, 95% CI 1.21 to 
      1.97), and mRS 0-2 (OR 1.84, 95% CI 1.52 to 2.22). BGC-treated patients also had 
      lower odds of mortality (OR 0.52, 95% CI 0.37 to 0.73) compared with non-BGC 
      patients. The mean number of passes was significantly lower for BGC-treated patients 
      (weighted mean difference -0.34, 95% CI-0.47 to -0.22). Mean procedure time was also 
      significantly shorter for BGC-treated patients (weighted mean difference -7.7 min, 
      95% CI-9.0to -6.4). CONCLUSIONS: Non-randomized studies suggest that BGC use during 
      mechanical thrombectomy for acute ischemic stroke is associated with superior 
      clinical and angiographic outcomes. Further randomized trials are needed to confirm 
      the results of this study.
CI  - © Article author(s) (or their employer(s) unless otherwise stated in the text of the 
      article) 2018. All rights reserved. No commercial use is permitted unless otherwise 
      expressly granted.
FAU - Brinjikji, Waleed
AU  - Brinjikji W
AD  - Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
AD  - Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA.
AD  - Department of Neuroradiology, Toronto Western Hospital, University of Toronto, 
      Toronto, Ontario, Canada.
FAU - Starke, Robert M
AU  - Starke RM
AD  - Department of Neurological Surgery, Miami Miller School of Medicine, University of 
      Miami Hospital, Miami, Florida, USA.
AD  - Department of Radiology, University of Miami Hospital, Miami Miller School of 
      Medicine, Miami, Florida, USA.
FAU - Murad, M Hassan
AU  - Murad MH
AD  - Evidence-based Practice Center, Mayo Clinic, Rochester, Minnesota, USA.
FAU - Fiorella, David
AU  - Fiorella D
AD  - Department of Neurosurgery, State University of New York at Stony Brook, Stony Brook 
      University Medical Center, Stony Brook, New York, USA.
FAU - Pereira, Vitor M
AU  - Pereira VM
AD  - Department of Neuroradiology, Toronto Western Hospital, University of Toronto, 
      Toronto, Ontario, Canada.
FAU - Goyal, Mayank
AU  - Goyal M
AD  - Department of Diagnostic Imaging, University of Calgary, Calgary, Alberta, Canada.
FAU - Kallmes, David F
AU  - Kallmes DF
AD  - Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
AD  - Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20170728
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Aged
MH  - Brain Ischemia/diagnostic imaging/*surgery
MH  - Catheterization/instrumentation/*methods
MH  - Clinical Trials as Topic/methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Stents
MH  - Stroke/diagnostic imaging/*surgery
MH  - Thrombectomy/instrumentation/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - mechanical thrombectomy
OT  - stroke
EDAT- 2017/07/30 06:00
MHDA- 2018/08/01 06:00
CRDT- 2017/07/30 06:00
PHST- 2017/05/05 00:00 [received]
PHST- 2017/06/02 00:00 [revised]
PHST- 2017/06/09 00:00 [accepted]
PHST- 2017/07/30 06:00 [pubmed]
PHST- 2018/08/01 06:00 [medline]
PHST- 2017/07/30 06:00 [entrez]
AID - neurintsurg-2017-013179 [pii]
AID - 10.1136/neurintsurg-2017-013179 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2018 Apr;10(4):335-339. doi: 10.1136/neurintsurg-2017-013179. 
      Epub 2017 Jul 28.

PMID- 26789499
OWN - NLM
STAT- MEDLINE
DCOM- 20170713
LR  - 20180412
IS  - 1527-1315 (Electronic)
IS  - 0033-8419 (Linking)
VI  - 280
IP  - 1
DP  - 2016 Jul
TI  - Comparison of a Balloon Guide Catheter and a Non-Balloon Guide Catheter for 
      Mechanical Thrombectomy.
PG  - 169-76
LID - 10.1148/radiol.2015150575 [doi]
AB  - Purpose To evaluate the effectiveness of mechanical thrombectomy with the use of a 
      stent retriever in acute ischemic stroke, performed by using a balloon guide 
      catheter or non-balloon guide catheter. Materials and Methods In accordance with the 
      institutional review board approval obtained at the two participating institutions, 
      retrospective analysis was performed in 183 consecutive patients treated between 
      2013 and 2014 for occlusions in the middle cerebral artery or carotid terminus by 
      using a stent retriever with a balloon guide catheter (n = 102) at one center and a 
      non-balloon guide catheter (n = 81) at the other center. Data on procedure duration, 
      number of passes, angiographic findings, type of stent retriever used, and expertise 
      of the operators were collected. Successful recanalization was defined as grade 3 or 
      2b modified Treatment in Cerebral Ischemia recanalization accomplished in up to 
      three passes. Univariate and multivariate subgroup analyses were conducted to 
      control for the confounding variables of prior thrombolysis, location of occlusion, 
      and operator expertise. Results Successful recanalization with the balloon guide 
      catheter was achieved in 89.2% of thrombectomies (91 of 102) versus 67.9% (55 of 81) 
      achieved with the non-balloon guide catheter (P = .0004). The one-pass thrombectomy 
      rate with the balloon guide catheter was significantly higher than for that with the 
      non-balloon guide catheter (63.7% [65 of 102] vs 35.8% [29 of 81], respectively; P = 
      .001). The procedure duration was significantly shorter by using the balloon guide 
      catheter than the non-balloon guide catheter (median, 20.5 minutes vs 41.0 minutes, 
      respectively; P < .0001). Conclusion The effectiveness of mechanical thrombectomy 
      with stent retrievers in acute ischemic stroke in the anterior circulation in terms 
      of angiographic results and procedure duration was improved when performed in 
      combination with the balloon guide catheter. (©) RSNA, 2016.
FAU - Velasco, Aglaé
AU  - Velasco A
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Buerke, Boris
AU  - Buerke B
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Stracke, Christian P
AU  - Stracke CP
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Berkemeyer, Shoma
AU  - Berkemeyer S
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Mosimann, Pascal J
AU  - Mosimann PJ
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Schwindt, Wolfram
AU  - Schwindt W
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Alcázar, Pedro
AU  - Alcázar P
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Cnyrim, Christian
AU  - Cnyrim C
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Niederstadt, Thomas
AU  - Niederstadt T
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Chapot, René
AU  - Chapot R
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
FAU - Heindel, Walter
AU  - Heindel W
AD  - From the Department of Clinical Radiology-Neuroradiology (A.V., B.B., S.B., W.S., 
      C.C., T.N., W.H.), University of Muenster, Albert-Schweitzer-Campus 1, Gebäude A1, 
      48149 Muenster, Germany; Department of Intracranial Endovascular Therapy and 
      Department of Neuroradiology, Alfried-Krupp Krankenhaus Hospital, Essen, Germany 
      (C.P.S., R.C.); Department of Neuroradiology and Interventional Neuroradiology, 
      University Hospital Virgen de las Nieves, Granada, Spain (P.A.); and Department of 
      Radiology, University Hospital of Lausanne, Lausanne, Switzerland (P.J.M.).
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
DEP - 20160120
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
SB  - AIM
SB  - IM
CIN - Radiology. 2017 Aug;284(2):607-608. PMID: 28723284
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Catheters
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - *Stents
MH  - Stroke/*surgery
MH  - Thrombectomy/*instrumentation/*methods
MH  - Young Adult
EDAT- 2016/01/21 06:00
MHDA- 2017/07/14 06:00
CRDT- 2016/01/21 06:00
PHST- 2016/01/21 06:00 [entrez]
PHST- 2016/01/21 06:00 [pubmed]
PHST- 2017/07/14 06:00 [medline]
AID - 10.1148/radiol.2015150575 [doi]
PST - ppublish
SO  - Radiology. 2016 Jul;280(1):169-76. doi: 10.1148/radiol.2015150575. Epub 2016 Jan 20.

PMID- 30712011
OWN - NLM
STAT- MEDLINE
DCOM- 20191126
LR  - 20191126
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 11
IP  - 9
DP  - 2019 Sep
TI  - Effect of balloon guide catheter on clinical outcomes and reperfusion in Trevo 
      thrombectomy.
PG  - 861-865
LID - 10.1136/neurintsurg-2018-014452 [doi]
AB  - INTRODUCTION: The Solitaire stent retriever registry showed improved reperfusion, 
      faster procedure times, and better outcome in acute stroke patients with large 
      vessel occlusion treated with a balloon guide catheter (BGC) and Solitaire stent 
      retriever compared with a conventional guide catheter. The goal of this study was to 
      evaluate whether use of a BGC with the Trevo stent retriever improves outcomes 
      compared with a conventional guide catheter. METHODS: The TRACK registry recruited 
      23 sites to submit demographic, clinical, and site adjudicated angiographic and 
      outcome data on consecutive patients treated with the Trevo stent retriever. BGC use 
      was at the discretion of the physician. RESULTS: 536 anterior circulation patients 
      (of whom 279 (52.1%) had BGC placement) were included in this analysis. Baseline 
      characteristics were notable for younger patients in the BGC group (65.4±15.3 vs 
      68.1±13.6, P=0.03) and lower rate of hypertension (72% vs 79%, P=0.06). Mean time 
      from symptom onset to groin puncture was longer in the BGC group (357 vs 319 min, 
      P=0.06).Thrombolysis in Cerebral Infarction 2b/3 scores were higher in the BGC 
      cohort (84% vs 75.5%, P=0.01). There was no difference in reperfusion time, first 
      pass effect, number of passes, or rescue therapy. Good clinical outcome at 3 months 
      was superior in patients with BGC (57% vs 40%; P=0.0004) with a lower mortality rate 
      (13% vs 23%, P=0.008). Multivariate analysis demonstrated that BGC use was an 
      independent predictor of good clinical outcome (OR 2; 95% CI 1.3 to 3.1, P=0.001). 
      CONCLUSIONS: In acute stroke patients presenting with anterior circulation large 
      vessel occlusion, use of a BGC with the Trevo stent retriever resulted in improved 
      reperfusion, improved clinical outcome, and lower mortality.
CI  - © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - Department of Neurology, Boston University School of Medicine, Boston, 
      Massachusetts, USA.
AD  - Department of Neurosurgery, Boston Medical Center, Boston, Massachusetts, USA.
AD  - Department of Radiology, Boston Medical Center, Boston, Massachusetts, USA.
FAU - Castonguay, Alicia C
AU  - Castonguay AC
AD  - Neurology, University of Toledo, Toledo, OH, US.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
FAU - English, Joey D
AU  - English JD
AD  - California Pacific Medical Center, San Francisco, California, USA.
FAU - Satti, Sudhakar R
AU  - Satti SR
AD  - Department of Neurointerventional Surgery, Christiana Care Health System, Newark, 
      Delaware, USA.
FAU - Chen, Jennifer
AU  - Chen J
AD  - Sidney Kimmel Medical School, Philadelphia, Pennsylvania, USA.
FAU - Farid, Hamed
AU  - Farid H
AD  - Department of Neurointerventional Radiology, St Jude Medical Center, Fullerton, USA.
FAU - Borders, Candace
AU  - Borders C
AD  - UC Irvine Health School of Medicine, Irvine, California, USA.
FAU - Veznedaroglu, Erol
AU  - Veznedaroglu E
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, 
      Pennsylvania, USA.
FAU - Binning, Mandy J
AU  - Binning MJ
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, 
      Pennsylvania, USA.
FAU - Puri, Ajit S
AU  - Puri AS
AD  - University of Massachusetts, Radiology, Worcester, Massachusetts, USA.
FAU - Vora, Nirav A
AU  - Vora NA
AD  - Department of Radiology, Riverside Radiology and Interventional Associates Inc, 
      Columbus, Ohio, USA.
FAU - Budzik, Ron F
AU  - Budzik RF
AD  - Department of Radiology, Riverside Radiology and Interventional Associates Inc, 
      Columbus, Ohio, USA.
FAU - Dabus, Guilherme
AU  - Dabus G
AD  - Department of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, 
      Miami, Florida, USA.
FAU - Linfante, Italo
AU  - Linfante I
AD  - Department of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, 
      Miami, Florida, USA.
FAU - Janardhan, Vallabh
AU  - Janardhan V
AD  - Texas Stroke Institute, Plano, Texas, USA.
FAU - Alshekhlee, Amer
AU  - Alshekhlee A
AD  - Department of Vascular and Interventional Neurology, DePaul Stroke Center-SSM 
      Neuroscience Institutes, St Louis University, St Louis, Missouri, USA.
FAU - Abraham, Michael G
AU  - Abraham MG
AD  - Departments of Neurology and Interventional Radiology, University of Kansas Medical 
      Center, Kansas, USA.
FAU - Edgell, Randall C
AU  - Edgell RC
AD  - Department of Neurology, St Louis University, St Louis, Missouri, USA.
FAU - Taqi, M Asif
AU  - Taqi MA
AD  - Department of Neurology and Neurosurgery, Los Robles Hospital and Medical Center, 
      Thousand Oaks, California, USA.
FAU - El Khoury, Ramy
AU  - El Khoury R
AD  - Department of Neurology, Tulane University, New Orleans, Louisiana, USA.
FAU - Mokin, Maxim
AU  - Mokin M
AD  - Department of Neurosurgery and Brain Repair, University of South Florida, South 
      Florida, Florida, USA.
FAU - Majjhoo, Aniel Q
AU  - Majjhoo AQ
AD  - Department of Neurology, Wayne State School of Medicine, Detroit, Michigan, USA.
FAU - Kabbani, Mouhammed R
AU  - Kabbani MR
AD  - Department of Neurosurgery, Gundersen Health System, La Crosse, Wisconsin, USA.
FAU - Froehler, Michael T
AU  - Froehler MT
AD  - Departments of Neurology, Neurosurgery, and Radiology, Vanderbilt University Medical 
      Center, Nashville, Tennessee, USA.
FAU - Finch, Ira
AU  - Finch I
AD  - John Muir Health, California, Walnut Creek, USA.
FAU - Ansari, Sameer A
AU  - Ansari SA
AD  - Departments of Radiology, Neurology, and Neurological Surgery, Northwestern 
      University, Feinberg School of Medicine, Chicago, Illinois, USA.
FAU - Novakovic, Roberta
AU  - Novakovic R
AD  - Departments of Radiology, Neurology, and Neurotherapeutics, UT Southwestern Medical 
      Center, Dallas, Texas, USA.
FAU - Abdalkader, Mohamad
AU  - Abdalkader M
AD  - Department of Neurology, Boston University School of Medicine, Boston, 
      Massachusetts, USA.
AD  - Department of Neurosurgery, Boston Medical Center, Boston, Massachusetts, USA.
AD  - Department of Radiology, Boston Medical Center, Boston, Massachusetts, USA.
FAU - Zaidat, Osama O
AU  - Zaidat OO
AUID- ORCID: 0000-0003-4881-4698
AD  - Departments of Endovascular Neurosurgery and Stroke, St Vincent Mercy Medical 
      Center, Toledo, Ohio, USA.
LA  - eng
PT  - Journal Article
DEP - 20190202
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Catheterization/instrumentation/*methods
MH  - Cohort Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Registries
MH  - Reperfusion/instrumentation/*methods
MH  - Retrospective Studies
MH  - Stroke/diagnostic imaging/*surgery
MH  - Thrombectomy/instrumentation/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - balloon
OT  - catheter
OT  - stroke
OT  - technique
OT  - thrombectomy
COIS- Competing interests: TNN is a consultant for Medtronic. OOZ is a consultant/advisory 
      board member for Stryker Neurovascular and Covidien. OOZ is overall principal 
      investigator for TRACK–no compensation and Arise II–modest. RGN is a 
      consultant/advisory board member for Stryker Neurovascular and Covidien. Stryker 
      Neurovascular (Trevo-2 trial principal investigator–modest; DAWN trial principal 
      investigator–no compensation, TREVO registry steering committee–no compensation), 
      Medtronic (SWIFT trial steering committee–modest; SWIFT-Prime trial steering 
      committee–no compensation; STAR Trial Angiographic Core Lab–significant), Penumbra 
      (3D Separator trial executive committee–no compensation), Neuravi (ARISE-2 steering 
      committee–no compensation), Genentech (physician advisory board–modest), Allm Inc 
      (physician advisory board–no compensation), editor- in-chief Interventional 
      Neurology journal (no compensation). SRS is a consultant for Stryker Neurovascular. 
      JDE is a consultant for Stryker Neurovascular.  IL is a consultant for Medtronic, 
      Stryker, Penumbra, and Cordis.
EDAT- 2019/02/04 06:00
MHDA- 2019/11/27 06:00
CRDT- 2019/02/04 06:00
PHST- 2018/09/28 00:00 [received]
PHST- 2018/12/19 00:00 [revised]
PHST- 2018/12/26 00:00 [accepted]
PHST- 2019/02/04 06:00 [pubmed]
PHST- 2019/11/27 06:00 [medline]
PHST- 2019/02/04 06:00 [entrez]
AID - neurintsurg-2018-014452 [pii]
AID - 10.1136/neurintsurg-2018-014452 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2019 Sep;11(9):861-865. doi: 10.1136/neurintsurg-2018-014452. 
      Epub 2019 Feb 2.

PMID- 28723284
OWN - NLM
STAT- MEDLINE
DCOM- 20180413
LR  - 20181202
IS  - 1527-1315 (Electronic)
IS  - 0033-8419 (Linking)
VI  - 284
IP  - 2
DP  - 2017 Aug
TI  - Balloon Guide Catheter in Large-Vessel Occlusion Stroke Therapy.
PG  - 607-608
LID - 10.1148/radiol.2017170375 [doi]
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - Departments of Neurology, Neurosurgery, and Radiology, 72 E Concord St, C-3, Boston 
      Medical Center, Boston, MA 02118.
FAU - Zaidat, Osama O
AU  - Zaidat OO
AD  - Departments of Neurology, Neurosurgery, and Radiology, 72 E Concord St, C-3, Boston 
      Medical Center, Boston, MA 02118.
LA  - eng
PT  - Comment
PT  - Journal Article
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
SB  - AIM
SB  - IM
CON - Radiology. 2016 Jul;280(1):169-76. PMID: 26789499
MH  - *Balloon Occlusion
MH  - Humans
MH  - *Stroke
EDAT- 2017/07/21 06:00
MHDA- 2018/04/14 06:00
CRDT- 2017/07/21 06:00
PHST- 2017/07/21 06:00 [entrez]
PHST- 2017/07/21 06:00 [pubmed]
PHST- 2018/04/14 06:00 [medline]
AID - 10.1148/radiol.2017170375 [doi]
PST - ppublish
SO  - Radiology. 2017 Aug;284(2):607-608. doi: 10.1148/radiol.2017170375.

PMID- 30497154
OWN - NLM
STAT- Publisher
LR  - 20191120
IS  - 1933-0693 (Electronic)
IS  - 0022-3085 (Linking)
DP  - 2018 Nov 1
TI  - Effect of balloon guide catheter utilization on contact aspiration thrombectomy.
PG  - 1-7
LID - 2018.6.JNS181045 [pii]
LID - 10.3171/2018.6.JNS181045 [doi]
AB  - OBJECTIVEThe role of the balloon guide catheter (BGC) has not been evaluated in 
      contact aspiration thrombectomy (CAT) for acute stroke. Here, the authors aimed to 
      test whether the BGC was associated with recanalization success and good functional 
      outcome in CAT.METHODSAll patients who had undergone CAT as the first-line treatment 
      for anterior circulation intracranial large vessel occlusion were retrospectively 
      identified from prospectively maintained registries for six stroke centers. The 
      patients were dichotomized into BGC utilization and nonutilization groups. Clinical 
      findings, procedural details, and recanalization success rates were compared between 
      the two groups. Whether the BGC was associated with recanalization success and 
      functional outcome was assessed.RESULTSA total of 429 patients (mean age 68.4 ± 11.4 
      years; M/F ratio 215:214) fulfilled the inclusion criteria. A BGC was used in 45.2% 
      of patients. The overall recanalization and good outcome rates were 80.2% and 52.0%, 
      respectively. Compared to the non-BGC group, the BGC group had a significantly 
      reduced number of CAT passes (2.6 ± 1.6 vs 3.4 ± 1.5), shorter 
      puncture-to-recanalization time (56 ± 27 vs 64 ± 35 minutes), lower need for the 
      additional use of thrombolytics (1.0% vs 8.1%), and less embolization to a distal or 
      different site (0.5% vs 3.4%). The BGC group showed significantly higher final 
      (89.2% vs 72.8%) and first-pass (24.2% vs 8.1%) recanalization success rates. After 
      adjustment for potentially associated factors, BGC utilization remained 
      independently associated with recanalization (OR 4.171, 95% CI 1.523-11.420) and 
      good functional outcome (OR 2.103, 95% CI 1.225-3.612).CONCLUSIONSBGC utilization 
      significantly increased the final and first-pass recanalization rates and remained 
      independently associated with recanalization success and good functional outcome.
FAU - Kang, Dong-Hun
AU  - Kang DH
AD  - Departments of1Neurosurgery and Radiology.
FAU - Kim, Byung Moon
AU  - Kim BM
AD  - Departments of2Radiology and.
FAU - Heo, Ji Hoe
AU  - Heo JH
AD  - 3Neurology, Severance Stroke Center, Severance Hospital, Yonsei University College 
      of Medicine, Seoul.
FAU - Nam, Hyo Suk
AU  - Nam HS
AD  - 3Neurology, Severance Stroke Center, Severance Hospital, Yonsei University College 
      of Medicine, Seoul.
FAU - Kim, Young Dae
AU  - Kim YD
AD  - 3Neurology, Severance Stroke Center, Severance Hospital, Yonsei University College 
      of Medicine, Seoul.
FAU - Hwang, Yang-Ha
AU  - Hwang YH
AD  - 4Neurology, and.
FAU - Kim, Yong-Won
AU  - Kim YW
AD  - 4Neurology, and.
FAU - Kim, Yong-Sun
AU  - Kim YS
AD  - 5Radiology, School of Medicine, Kyungpook National University, Daegu.
FAU - Kim, Dong Joon
AU  - Kim DJ
AD  - Departments of2Radiology and.
FAU - Kwak, Hyo Sung
AU  - Kwak HS
AD  - 6Department of Radiology, Chonbuk National University Medical School and Hospital, 
      Jeonju.
FAU - Roh, Hong Gee
AU  - Roh HG
AD  - 7Department of Radiology, Konkuk University Medical Center, Seoul.
FAU - Lee, Young-Jun
AU  - Lee YJ
AD  - 8Department of Radiology, Hanyang University Medical School and Hospital, Seoul; 
      and.
FAU - Kim, Sang Heum
AU  - Kim SH
AD  - 9Department of Radiology, CHA Bundang Medical Center, CHA University, Seongnam, 
      South Korea.
LA  - eng
PT  - Journal Article
DEP - 20181101
PL  - United States
TA  - J Neurosurg
JT  - Journal of neurosurgery
JID - 0253357
OTO - NOTNLM
OT  - ASPECTS = Alberta Stroke Program Early CT Score
OT  - BGC = balloon guide catheter
OT  - CAT = contact aspiration thrombectomy
OT  - CRF = case report form
OT  - EVT = endovascular thrombectomy
OT  - ICA = internal carotid artery
OT  - LVO = large vessel occlusion
OT  - MCA = middle cerebral artery
OT  - NIHSS = National Institutes of Health Stroke Scale
OT  - OPT = onset-to-puncture time
OT  - PRT = puncture-to-recanalization time
OT  - RCT = randomized controlled trial
OT  - acute stroke
OT  - aspiration catheter
OT  - balloon guide catheter
OT  - interventional neurosurgery
OT  - mRS = modified Rankin Scale
OT  - mTICI modified Thrombolysis in Cerebral Infarction
OT  - tPA = tissue plasminogen activator
OT  - thrombectomy
OT  - vascular disorders
EDAT- 2018/12/01 06:00
MHDA- 2018/12/01 06:00
CRDT- 2018/12/01 06:00
PHST- 2018/04/17 00:00 [received]
PHST- 2018/06/11 00:00 [accepted]
PHST- 2018/12/01 06:00 [pubmed]
PHST- 2018/12/01 06:00 [medline]
PHST- 2018/12/01 06:00 [entrez]
AID - 2018.6.JNS181045 [pii]
AID - 10.3171/2018.6.JNS181045 [doi]
PST - aheadofprint
SO  - J Neurosurg. 2018 Nov 1:1-7. doi: 10.3171/2018.6.JNS181045.

PMID- 31043149
OWN - NLM
STAT- MEDLINE
DCOM- 20200122
LR  - 20200122
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 50
IP  - 6
DP  - 2019 Jun
TI  - Balloon Guide Catheter Is Beneficial in Endovascular Treatment Regardless of 
      Mechanical Recanalization Modality.
PG  - 1490-1496
LID - 10.1161/STROKEAHA.118.024723 [doi]
AB  - Background and Purpose- Based on its mechanism, the use of balloon guide catheters 
      (BGCs) may be beneficial during endovascular treatment, regardless of the type of 
      mechanical recanalization modality used-stent retriever thrombectomy or 
      thrombaspiration. We evaluated whether the use of BGCs can be beneficial regardless 
      of the first-line mechanical endovascular modality used. Methods- We retrospectively 
      reviewed consecutive acute stroke patients who underwent stent retriever 
      thrombectomy or thrombaspiration from the prospectively maintained registries of 17 
      stroke centers nationwide. Patients were assigned to the BGC or non-BGC group based 
      on the use of BGCs during procedures. Endovascular and clinical outcomes were 
      compared between the BGC and non-BGC groups. To adjust the influence of the type of 
      first-line endovascular modality on successful recanalization and favorable outcome, 
      multivariable analyses were also performed. Results- This study included a total of 
      955 patients. Stent retriever thrombectomy was used as the first-line modality in 
      526 patients (55.1%) and thrombaspiration in 429 (44.9%). BGC was used in 516 
      patients (54.0%; 61.2% of stent retriever thrombectomy patients; 45.2% of 
      thrombaspiration patients). The successful recanalization rate was significantly 
      higher in the BGC group compared with the non-BGC group (86.8% versus 74.7%, 
      respectively; P<0.001). Furthermore, the first-pass recanalization rate was more 
      frequent (37.0% versus 14.1%; P<0.001), and the number of device passes was fewer in 
      the BGC group (2.5±1.9 versus 3.3±2.1; P<0.001). The procedural time was also 
      shorter in the BGC group (54.3±27.4 versus 67.6±38.2; P<0.001). The use of BGC was 
      an independent factor for successful recanalization (odds ratio, 2.18; 95% CI, 
      1.54-3.10; P<0.001) irrespective of the type of first-line endovascular modality 
      used. The use of BGC was also an independent factor for a favorable outcome (odds 
      ratio, 1.40; 95% CI, 1.02-1.92; P=0.038) irrespective of the type of first-line 
      endovascular modality used. Conclusions- Regardless of the first-line mechanical 
      endovascular modality used, the use of BGC in endovascular treatment was beneficial 
      in terms of both recanalization success and functional outcome.
FAU - Baek, Jang-Hyun
AU  - Baek JH
AD  - From the Department of Neurology, Kangbuk Samsung Hospital (J.-H.B.), Sungkyunkwan 
      University School of Medicine, Seoul, Korea.
AD  - Departments of Neurology (J.-H.B., J.H.H., H.S.N., Y.D.K.), Yonsei University 
      College of Medicine, Seoul, Korea.
FAU - Kim, Byung Moon
AU  - Kim BM
AD  - Radiology (B.M.K., D.J.K.), Yonsei University College of Medicine, Seoul, Korea.
FAU - Kang, Dong-Hun
AU  - Kang DH
AD  - Departments of Neurosurgery (D.-H.K.), Kyungpook National University Hospital, 
      Daegu, Korea.
AD  - Radiology (D.-H.K., Y.-S.K.), Kyungpook National University Hospital, Daegu, Korea.
FAU - Heo, Ji Hoe
AU  - Heo JH
AD  - Departments of Neurology (J.-H.B., J.H.H., H.S.N., Y.D.K.), Yonsei University 
      College of Medicine, Seoul, Korea.
FAU - Nam, Hyo Suk
AU  - Nam HS
AD  - Departments of Neurology (J.-H.B., J.H.H., H.S.N., Y.D.K.), Yonsei University 
      College of Medicine, Seoul, Korea.
FAU - Kim, Young Dae
AU  - Kim YD
AD  - Departments of Neurology (J.-H.B., J.H.H., H.S.N., Y.D.K.), Yonsei University 
      College of Medicine, Seoul, Korea.
FAU - Hwang, Yang-Ha
AU  - Hwang YH
AD  - Neurology (Y.-H.H., Y.-W.K.), Kyungpook National University Hospital, Daegu, Korea.
FAU - Kim, Yong-Won
AU  - Kim YW
AD  - Neurology (Y.-H.H., Y.-W.K.), Kyungpook National University Hospital, Daegu, Korea.
FAU - Kim, Yong-Sun
AU  - Kim YS
AD  - Radiology (D.-H.K., Y.-S.K.), Kyungpook National University Hospital, Daegu, Korea.
FAU - Kim, Dong Joon
AU  - Kim DJ
AD  - Radiology (B.M.K., D.J.K.), Yonsei University College of Medicine, Seoul, Korea.
FAU - Kwak, Hyo Sung
AU  - Kwak HS
AD  - Department of Radiology, Chonbuk National University Medical School and Hospital, 
      Jeonju, Korea (H.S.K.).
FAU - Roh, Hong Gee
AU  - Roh HG
AD  - Department of Radiology, Konkuk University Hospital, Seoul, Korea (H.G.R.).
FAU - Lee, Young-Jun
AU  - Lee YJ
AD  - Department of Radiology, Hanyang University Hospital, Seoul, Korea (Y.-J.L.).
FAU - Kim, Sang Heum
AU  - Kim SH
AD  - Department of Radiology, CHA Bundang Medical Center, CHA University School of 
      Medicine, Seongnam, Korea (S.H.K.).
FAU - Baik, Seung Kug
AU  - Baik SK
AD  - Department of Radiology, Pusan National University Yangsan Hospital, Korea (S.K.B.).
FAU - Jeon, Pyoung
AU  - Jeon P
AD  - Department of Radiology, Samsung Medical Center (P.J.), Sungkyunkwan University 
      School of Medicine, Seoul, Korea.
FAU - Yoo, Joonsang
AU  - Yoo J
AD  - Department of Neurology, Keimyung University Dongsan Medical Center, Daegu, Republic 
      of Korea (J.Y.).
FAU - Suh, Sang Hyun
AU  - Suh SH
AD  - Severance Hospital Stroke Center, and Department of Radiology, Gangnam Severance 
      Hospital (S.H.S.), Yonsei University College of Medicine, Seoul, Korea.
FAU - Kim, Byungjun
AU  - Kim B
AD  - Department of Radiology, Korea University Anam Hospital, Seoul (B.K.).
FAU - Kim, Jin Woo
AU  - Kim JW
AD  - Department of Radiology, Inje University Ilsan Paik Hospital, Goyang, Korea 
      (J.W.K.).
FAU - Suh, Sangil
AU  - Suh S
AD  - Department of Radiology, Korea University Guro Hospital, Seoul (S.S.).
FAU - Jeon, Hong-Jun
AU  - Jeon HJ
AD  - Department of Neurosurgery, Kangdong Sacred Heart Hospital, Hallym University 
      College of Medicine, Seoul, Korea (H.-J.J.).
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20190502
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
MH  - Aged
MH  - *Angioplasty, Balloon
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Registries
MH  - Retrospective Studies
MH  - Stroke/epidemiology/*surgery
MH  - *Thrombectomy
OTO - NOTNLM
OT  - *balloon occlusion
OT  - *endovascular treatment
OT  - *stroke
OT  - *thrombectomy
EDAT- 2019/05/03 06:00
MHDA- 2020/01/23 06:00
CRDT- 2019/05/03 06:00
PHST- 2019/05/03 06:00 [pubmed]
PHST- 2020/01/23 06:00 [medline]
PHST- 2019/05/03 06:00 [entrez]
AID - 10.1161/STROKEAHA.118.024723 [doi]
PST - ppublish
SO  - Stroke. 2019 Jun;50(6):1490-1496. doi: 10.1161/STROKEAHA.118.024723. Epub 2019 May 
      2.

PMID- 31648562
OWN - NLM
STAT- MEDLINE
DCOM- 20200110
LR  - 20200110
IS  - 1745-2422 (Electronic)
IS  - 1743-4440 (Linking)
VI  - 16
IP  - 11
DP  - 2019 Nov
TI  - Optimizing fast first pass complete reperfusion in acute ischemic stroke - the 
      BADDASS approach (BAlloon guiDe with large bore Distal Access catheter with dual 
      aspiration with Stent-retriever as Standard approach).
PG  - 955-963
LID - 10.1080/17434440.2019.1684263 [doi]
AB  - Introduction: Endovascular therapy is the standard of care for acute ischemic stroke 
      due to large vessel occlusions. The ultimate goal is to achieve fast first pass 
      complete reperfusion, since delayed and/or incomplete reperfusion increases 
      complication rates and costs and deteriorates patient outcome. Achieving optimal 
      results can sometimes be challenging, particularly in patients with tortuous 
      vessels. Several techniques have been described lately to optimize recanalization, 
      including first line aspiration and various stent-retriever assisted techniques. In 
      our experience, mechanical thrombectomy with a BAlloon guide catheter, large bore 
      Distal access catheter, Dual Aspiration and Stent-retriever as Standard approach 
      (BADDASS) is the most efficient technique to succeed, since it combines the 
      advantages of stent-retrievers and distal aspiration.Areas covered: The purpose of 
      this review is to enable neurointerventionalists to achieve fast first pass complete 
      reperfusion by outlining the BADDASS approach step-by-step and sharing additional 
      tips for navigating through challenging internal carotid artery segments.Expert 
      opinion: In our experience, the BADDASS approach is the safest and most effective 
      way to achieve fast first pass complete reperfusion.
FAU - Ospel, J M
AU  - Ospel JM
AD  - Department of Radiology, University Hospital Basel, University of Basel, Basel, 
      Switzerland.
AD  - Department of Radiology, University of Calgary, Calgary, Canada.
FAU - Volny, O
AU  - Volny O
AD  - Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
AD  - International Clinical Research Centre, Stroke Research Program, St. Anne´s 
      University Hospital, Brno, Czech Republic.
AD  - Department of Neurology, St. Anne´s University Hospital and Faculty of Medicine, 
      Masaryk University, Brno, Czech Republic.
FAU - Jayaraman, M
AU  - Jayaraman M
AD  - Department of Diagnostic Imaging, Warren Alpert School of Medicine at Brown 
      University, Providence, RI, USA.
AD  - Department of Neurology, Warren Alpert School of Medicine at Brown University, 
      Providence, RI, USA.
AD  - Department of Neurosurgery, Warren Alpert School of Medicine at Brown University, 
      Providence, RI, USA.
AD  - The Norman Prince Neuroscience Institute, Rhode Island Hospital, Providence, RI, 
      USA.
FAU - McTaggart, R
AU  - McTaggart R
AD  - Department of Diagnostic Imaging, Warren Alpert School of Medicine at Brown 
      University, Providence, RI, USA.
AD  - Department of Neurology, Warren Alpert School of Medicine at Brown University, 
      Providence, RI, USA.
AD  - Department of Neurosurgery, Warren Alpert School of Medicine at Brown University, 
      Providence, RI, USA.
AD  - The Norman Prince Neuroscience Institute, Rhode Island Hospital, Providence, RI, 
      USA.
FAU - Goyal, M
AU  - Goyal M
AD  - Department of Radiology, University of Calgary, Calgary, Canada.
AD  - Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20191031
PL  - England
TA  - Expert Rev Med Devices
JT  - Expert review of medical devices
JID - 101230445
SB  - IM
MH  - Brain Ischemia/*complications/*therapy
MH  - *Cardiac Catheterization
MH  - Humans
MH  - *Reperfusion
MH  - *Stents/adverse effects
MH  - Stroke/*complications/*therapy
MH  - Suction
OTO - NOTNLM
OT  - Aspiration
OT  - balloon guide catheter
OT  - endovascular therapy
OT  - ischemic stroke
OT  - reperfusion
OT  - thrombectomy
EDAT- 2019/10/28 06:00
MHDA- 2020/01/11 06:00
CRDT- 2019/10/26 06:00
PHST- 2019/10/28 06:00 [pubmed]
PHST- 2020/01/11 06:00 [medline]
PHST- 2019/10/26 06:00 [entrez]
AID - 10.1080/17434440.2019.1684263 [doi]
PST - ppublish
SO  - Expert Rev Med Devices. 2019 Nov;16(11):955-963. doi: 10.1080/17434440.2019.1684263. 
      Epub 2019 Oct 31.

PMID- 31542275
OWN - NLM
STAT- MEDLINE
DCOM- 20200302
LR  - 20200302
IS  - 1535-7732 (Electronic)
IS  - 1051-0443 (Linking)
VI  - 30
IP  - 11
DP  - 2019 Nov
TI  - Balloon Guide Catheter in Endovascular Treatment for Acute Ischemic Stroke: Results 
      from the MR CLEAN Registry.
PG  - 1759-1764.e6
LID - S1051-0443(19)30544-5 [pii]
LID - 10.1016/j.jvir.2019.05.032 [doi]
AB  - PURPOSE: To compare outcomes after endovascular treatment (EVT) for acute ischemic 
      stroke with and without the use of a balloon guide catheter (BGC) in clinical 
      practice. MATERIALS AND METHODS: Data from the Multicenter Randomized Clinical Trial 
      of Endovascular Treatment for Acute Ischemic Stroke in The Netherlands (MR CLEAN) 
      Registry were used, in which all patients who underwent EVT for anterior-circulation 
      stroke in The Netherlands between 2014 and 2016 were enrolled. Primary outcome was 
      modified Rankin scale (mRS) score at 90 days. Secondary outcomes included 
      reperfusion grade (extended Thrombolysis In Cerebral Infarction [eTICI] score) and 
      National Institutes of Health Stroke Scale (NIHSS) score 24-48 hours after 
      intervention. The association between the use of a BGC and outcomes was estimated 
      with logistic regression adjusted for age, sex, prestroke mRS score, NIHSS score, 
      collateral grade, and time from onset to EVT. RESULTS: A total of 887 patients were 
      included. Thrombectomy was performed with the use of a BGC in 528 patients (60%) and 
      without in 359 patients (40%). There was no significant association between use of a 
      BGC and a shift on the mRS toward better outcome (adjusted common odds ratio, 1.17; 
      95% confidence interval [CI], 0.91-1.52). Use of a BGC was associated with higher 
      eTICI score (adjusted common OR, 1.33; 95% CI, 1.04-1.70) and improvement of ≥ 4 
      points on the NIHSS (adjusted OR, 1.40; 95% CI, 1.04-1.88). CONCLUSIONS: In clinical 
      practice, use of a BGC was associated with higher reperfusion grade and early 
      improvement of neurologic deficits, but had no positive effect on long-term 
      functional outcome.
CI  - Copyright © 2019 SIR. All rights reserved.
FAU - Goldhoorn, Robert-Jan B
AU  - Goldhoorn RB
AD  - Department of Neurology, Maastricht University Medical Center and Cardiovascular 
      Research Institute Maastricht, Room 4.R1.032, P. Debyelaan 25, 6229 HX Maastricht, 
      The Netherlands. Electronic address: robertjan.goldhoorn@mumc.nl.
FAU - Duijsters, Nele
AU  - Duijsters N
AD  - Department of Neurology, Maastricht University Medical Center and Cardiovascular 
      Research Institute Maastricht, Room 4.R1.032, P. Debyelaan 25, 6229 HX Maastricht, 
      The Netherlands.
FAU - Majoie, Charles B L M
AU  - Majoie CBLM
AD  - Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, 
      Amsterdam, The Netherlands.
FAU - Roos, Yvo B W E M
AU  - Roos YBWEM
AD  - Department of Neurology, Amsterdam University Medical Center, Amsterdam, The 
      Netherlands.
FAU - Dippel, Diederik W J
AU  - Dippel DWJ
AD  - Department of Neurology, Erasmus University Medical Center, University Medical 
      Center, Rotterdam, The Netherlands.
FAU - van Es, Adriaan C G M
AU  - van Es ACGM
AD  - Department of Radiology, Erasmus University Medical Center, University Medical 
      Center, Rotterdam, The Netherlands.
FAU - Vos, Jan Albert
AU  - Vos JA
AD  - Department of Radiology, Sint Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Boiten, Jelis
AU  - Boiten J
AD  - Department of Neurology, Haaglanden Medical Center, The Hague, The Netherlands.
FAU - van Oostenbrugge, Robert J
AU  - van Oostenbrugge RJ
AD  - Department of Neurology, Maastricht University Medical Center and Cardiovascular 
      Research Institute Maastricht, Room 4.R1.032, P. Debyelaan 25, 6229 HX Maastricht, 
      The Netherlands.
FAU - van Zwam, Wim H
AU  - van Zwam WH
AD  - Department of Radiology, Maastricht University Medical Center and Cardiovascular 
      Research Institute Maastricht, Room 4.R1.032, P. Debyelaan 25, 6229 HX Maastricht, 
      The Netherlands.
CN  - MR CLEAN Registry Investigators
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20190918
PL  - United States
TA  - J Vasc Interv Radiol
JT  - Journal of vascular and interventional radiology : JVIR
JID - 9203369
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Ischemia/diagnostic imaging/physiopathology/*therapy
MH  - Cerebrovascular Circulation
MH  - Disability Evaluation
MH  - Endovascular Procedures/adverse effects/*instrumentation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Netherlands
MH  - Randomized Controlled Trials as Topic
MH  - Recovery of Function
MH  - Registries
MH  - Stents
MH  - Stroke/diagnostic imaging/physiopathology/*therapy
MH  - Thrombectomy/adverse effects/*instrumentation
MH  - Time Factors
MH  - Treatment Outcome
MH  - *Vascular Access Devices
EDAT- 2019/09/23 06:00
MHDA- 2020/03/03 06:00
CRDT- 2019/09/23 06:00
PHST- 2019/02/27 00:00 [received]
PHST- 2019/05/27 00:00 [revised]
PHST- 2019/05/31 00:00 [accepted]
PHST- 2019/09/23 06:00 [pubmed]
PHST- 2020/03/03 06:00 [medline]
PHST- 2019/09/23 06:00 [entrez]
AID - S1051-0443(19)30544-5 [pii]
AID - 10.1016/j.jvir.2019.05.032 [doi]
PST - ppublish
SO  - J Vasc Interv Radiol. 2019 Nov;30(11):1759-1764.e6. doi: 10.1016/j.jvir.2019.05.032. 
      Epub 2019 Sep 18.

PMID- 30410509
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1664-9737 (Print)
IS  - 1664-5545 (Electronic)
IS  - 1664-5545 (Linking)
VI  - 7
IP  - 6
DP  - 2018 Oct
TI  - Endovascular Acute Ischemic Stroke Treatment with FlowGate Balloon Guide Catheter: A 
      Single-Center Observational Study of FlowGate Balloon Guide Catheter Use.
PG  - 327-333
LID - 10.1159/000488601 [doi]
AB  - BACKGROUND: Treatment of large vessel occlusion acute ischemic stroke with 
      mechanical thrombectomy has become the standard of care after recent clinical 
      trials. However, the degree of recanalization with stent retrievers remains very 
      important in overall outcomes. We sought to review the utility of a new balloon 
      guide catheter (BGC) in improving the degree of recanalization in conjunction with 
      mechanical thrombectomy. METHODS: The medical records of a prospectively collected 
      endovascular ischemic stroke database were reviewed. All consecutive strokes when a 
      FlowGate BGC was used with a thrombectomy stent retriever were identified. Use of a 
      FlowGate BGC, number of passes, final Thrombolysis in Cerebral Infarction (TICI) 
      score, trackability, and use of adjunct devices were all collected and analyzed. 
      RESULTS: Use of a FlowGate BGC resulted in 64% (33/52) first-pass effect (FPE) of 
      TICI 2b/3, and specifically 46% (24/52) TICI 3 FPE (true FPE). A total of 52/62 
      (84%) of thrombectomy cases were treated with BGCs. In the remaining 10, the BGC was 
      not inflated or used due to the clot not being visualized or the lesions being 
      distal and BGC use thus not deemed appropriate. Adjunct use of an aspiration 
      catheter was seen in 12% (6/52) of cases. The overall success with FlowGate BGCs 
      with one or more passes of TICI 2b/3 was 94% (49/52). Trackability was achieved in 
      92% (57/62) of cases. CONCLUSIONS: Use of the FlowGate BGC as an adjunct to 
      mechanical thrombectomy was associated with good FPE and an overall recanalization 
      of TICI 2b/3 of 94%.
FAU - Teleb, Mohamed S
AU  - Teleb MS
AD  - Neurointerventional Surgery, Stroke, and Neurocritical Care, Banner Health, Mesa, 
      Arizona, USA.
LA  - eng
PT  - Journal Article
DEP - 20180516
TA  - Interv Neurol
JT  - Interventional neurology
JID - 101606828
PMC - PMC6216708
OTO - NOTNLM
OT  - Acute stroke
OT  - Balloon guide catheter
OT  - First pass
OT  - Stent
OT  - Thrombectomy
EDAT- 2018/11/10 06:00
MHDA- 2018/11/10 06:01
CRDT- 2018/11/10 06:00
PHST- 2017/09/03 00:00 [received]
PHST- 2018/03/19 00:00 [accepted]
PHST- 2018/11/10 06:00 [entrez]
PHST- 2018/11/10 06:00 [pubmed]
PHST- 2018/11/10 06:01 [medline]
AID - ine-0007-0327 [pii]
AID - 10.1159/000488601 [doi]
PST - ppublish
SO  - Interv Neurol. 2018 Oct;7(6):327-333. doi: 10.1159/000488601. Epub 2018 May 16.

PMID- 30309845
OWN - NLM
STAT- MEDLINE
DCOM- 20191104
LR  - 20191104
IS  - 1936-959X (Electronic)
IS  - 0195-6108 (Linking)
VI  - 39
IP  - 11
DP  - 2018 Nov
TI  - Balloon-Guide Catheters Are Needed for Effective Flow Reversal during Mechanical 
      Thrombectomy.
PG  - 2077-2081
LID - 10.3174/ajnr.A5829 [doi]
AB  - BACKGROUND AND PURPOSE: Blood flow management in the carotid artery during 
      mechanical thrombectomy is crucial for safety and effectiveness. There is an ongoing 
      discussion about whether balloon-guide catheters or large-bore sheaths are needed 
      for effective flow management. We compared general flow characteristics of proximal 
      aspiration through a large-bore sheath and a balloon-guide catheter in a porcine in 
      vivo model. MATERIALS AND METHODS: We investigated blood flow in a porcine common 
      carotid artery with and without aspiration (VacLok syringe and Penumbra pump, Pump 
      MAX) through an 8F-long sheath and an 8F balloon-guide catheter. Blood hemodynamics 
      were assessed via continuous duplex sonography. RESULTS: Average vessel diameter and 
      baseline blood flow were 4.4 ± 0.2 mm and 244 ± 20 mL/min, respectively. For the 8F 
      sheath, pump aspiration resulted in a significant flow reduction (225 ± 25 mL/min, P 
      < .001), but with a persisting antegrade stream. Manual aspiration resulted in 
      collapse of the vessel in 2 of 7 measurements and oscillatory flow with antegrade 
      systolic and retrograde diastolic components in the remaining 5 measurements. Net 
      flow was antegrade (52 ± 44 mL/min) in 3 and retrograde (-95 ± 52 mL/min) in the 
      remaining 2 measurements. For balloon-guide catheters, balloon inflation always 
      resulted in flow arrest. Additional pump or manual aspiration resulted in 
      significant flow reversal of -1100 ± 230 and -468 ± 46 mL/min, respectively (both, P 
      < .001). CONCLUSIONS: Only balloon-guide catheters allow reliable blood flow arrest 
      and flow reversal in combination with aspiration via syringes or high-flow pump 
      systems. Aspiration through an 8F sheath results in either collapse of the vessel or 
      oscillatory flow, which can result in a net antegrade or retrograde stream.
CI  - © 2018 by American Journal of Neuroradiology.
FAU - Nikoubashman, O
AU  - Nikoubashman O
AUID- ORCID: 0000-0002-2055-4217
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.) onikoubashman@ukaachen.de.
FAU - Wischer, D
AU  - Wischer D
AUID- ORCID: 0000-0002-7787-2101
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.).
FAU - Hennemann, H M
AU  - Hennemann HM
AUID- ORCID: 0000-0002-9175-972X
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.).
FAU - Sandmann, J
AU  - Sandmann J
AUID- ORCID: 0000-0001-6652-7655
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.).
FAU - Sichtermann, T
AU  - Sichtermann T
AUID- ORCID: 0000-0002-9115-9548
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.).
FAU - Müschenich, F S
AU  - Müschenich FS
AUID- ORCID: 0000-0001-7582-060X
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.).
FAU - Reich, A
AU  - Reich A
AUID- ORCID: 0000-0002-9439-7963
AD  - Neurology (A.R.), RWTH Aachen University Hospital, Aachen, Germany.
FAU - Wiesmann, M
AU  - Wiesmann M
AUID- ORCID: 0000-0002-8261-5513
AD  - From the Departments of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., J.S., T.S., F.S.M., M.W.).
LA  - eng
PT  - Journal Article
DEP - 20181011
PL  - United States
TA  - AJNR Am J Neuroradiol
JT  - AJNR. American journal of neuroradiology
JID - 8003708
SB  - IM
MH  - Animals
MH  - Carotid Artery, Common/surgery
MH  - *Catheters
MH  - *Cerebrovascular Circulation
MH  - Female
MH  - Stents
MH  - Stroke/surgery
MH  - Swine
MH  - Thrombectomy/*instrumentation/methods
EDAT- 2018/10/13 06:00
MHDA- 2019/11/05 06:00
CRDT- 2018/10/13 06:00
PHST- 2018/04/30 00:00 [received]
PHST- 2018/08/13 00:00 [accepted]
PHST- 2018/10/13 06:00 [pubmed]
PHST- 2019/11/05 06:00 [medline]
PHST- 2018/10/13 06:00 [entrez]
AID - ajnr.A5829 [pii]
AID - 10.3174/ajnr.A5829 [doi]
PST - ppublish
SO  - AJNR Am J Neuroradiol. 2018 Nov;39(11):2077-2081. doi: 10.3174/ajnr.A5829. Epub 2018 
      Oct 11.

PMID- 31602354
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200108
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 11
IP  - 8
DP  - 2019 Aug 8
TI  - Predictors of Balloon Guide Catheter Assistance Success in Stent-retrieval 
      Thrombectomy for an Anterior Circulation Acute Ischemic Stroke.
PG  - e5350
LID - 10.7759/cureus.5350 [doi]
LID - e5350
AB  - Introduction Mechanical thrombectomy has become the standard treatment for large 
      vessel occlusion (LVO) in acute ischemic stroke (AIS) in well-selected patients. 
      Although many devices and strategies exist, the use of a balloon-tip guide catheter 
      (BGC) with stent-retriever (SR) may hold several advantages. We aim to assess the 
      efficacy and identify predictors of technical success of this unique approach. 
      Methods From our prospectively maintained database, we identified consecutive cases 
      in which a BGC was used for stent-retriever thrombectomy in anterior circulation 
      LVO between 2015 and 2016. Baseline and procedural characteristics were captured and 
      analyzed. Predictors of technical and clinical outcomes were identified by 
      multivariable logistic regression analysis. Results Ninety-three patients with 
      AIS-LVO were treated with BGC-assisted mechanical thrombectomy. The mean age was 71 
      years old (SD 14), with 49.5% male (n=46). Pre-operative IV-tPA was administered in 
      55.9% (n=52) of cases. The most common location of occlusive thrombus was M1 (64.5%, 
      n=60). Successful recanalization (mTICI=2b-3) was achieved in 86.0% (n=80) of cases 
      while complete revascularization (mTICI-3) was achieved in 56.5% (n=52). There was a 
      first-pass success rate of 52.7% (n=49). At discharge, 38.7% of the patients were 
      functionally independent (mRS≤2). Multivariate analysis revealed that the middle 
      cerebral artery location was strongly predictive of first-pass success, resulting 
      in mTICI =2b revascularization (OR 7.10, p=0.018). Additionally, female gender (OR 
      2.85, p=0.042) and decreasing mTICI were associated with a poor clinical outcome 
      (mRS≥4; OR 1.76, p=0.008). Conclusions BGC assistance in stent retrieval 
      thrombectomy is safe and effective for AIS due to anterior circulation LVO. Further 
      investigation is required to elucidate the optimal treatment strategy based on 
      patient and disease characteristics.
CI  - Copyright © 2019, McCarthy et al.
FAU - McCarthy, David J
AU  - McCarthy DJ
AD  - Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
FAU - Sur, Samir
AU  - Sur S
AD  - Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
FAU - Fortunel, Adisson
AU  - Fortunel A
AD  - Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
FAU - Snelling, Brian
AU  - Snelling B
AD  - Neurosurgery, Boca Raton Regional Hospital, Boca Raton, USA.
FAU - Luther, Evan
AU  - Luther E
AD  - Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
FAU - Yavagal, Dileep
AU  - Yavagal D
AD  - Neuroendovascular Surgery, University of Miami Miller School of Medicine, Miami, 
      USA.
FAU - Peterson, Eric
AU  - Peterson E
AD  - Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
FAU - Starke, Robert M
AU  - Starke RM
AD  - Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
LA  - eng
PT  - Journal Article
DEP - 20190808
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC6779151
OTO - NOTNLM
OT  - balloon guide
OT  - ischemia
OT  - large vessel occlusion
OT  - mechanical thrombectomy
OT  - outcomes
OT  - stent retriever
OT  - stroke
COIS- The authors have declared that no competing interests exist.
EDAT- 2019/10/12 06:00
MHDA- 2019/10/12 06:01
CRDT- 2019/10/12 06:00
PHST- 2019/10/12 06:00 [entrez]
PHST- 2019/10/12 06:00 [pubmed]
PHST- 2019/10/12 06:01 [medline]
AID - 10.7759/cureus.5350 [doi]
PST - epublish
SO  - Cureus. 2019 Aug 8;11(8):e5350. doi: 10.7759/cureus.5350.

PMID- 29238099
OWN - NLM
STAT- MEDLINE
DCOM- 20181211
LR  - 20181211
IS  - 0027-7622 (Print)
IS  - 2186-3326 (Electronic)
IS  - 0027-7622 (Linking)
VI  - 79
IP  - 4
DP  - 2017 Nov
TI  - 8-F balloon guide catheter for embolization of anterior circulation aneurysms: an 
      institutional experience in 152 patients.
PG  - 435-441
LID - 10.18999/nagjms.79.4.435 [doi]
AB  - The use of 8-F balloon guide catheter (BGC) for proximal flow control was previously 
      shown to prevent distal embolic complications during mechanical clot retrieval in 
      patients with acute ischemic stroke. In this retrospective study, the utility of 8-F 
      BGCs for proximal flow control during endovascular coiling of anterior circulation 
      aneurysms was investigated. Patients who underwent endovascular coiling for anterior 
      circulation aneurysms between August 2013 and December 2016 were retrospectively 
      analyzed. Among a total of 152 patients included in this series, 64 patients 
      presented with aneurysmal rupture, whereas the aneurysms were detected incidentally 
      or due to mass effects in the remaining patients. 8-F BGCs were successfully 
      navigated in all patients. The balloon was inflated during navigation in 19 
      patients. Inflation of the catheter balloon during coil embolization was required in 
      34 patients; this was performed as an emergency maneuver in six of these patients. 
      Thromboembolic complications occurred in one patient. 8-F BGC can be effectively 
      used for proximal flow control during endovascular treatment of anterior circulation 
      aneurysms. The other advantages included improved navigation of tortuous arterial 
      anatomy, coil stabilization during aneurysmal coiling, and freedom to utilize 
      aneurysmal neck-remodeling balloons for additional adjunctive techniques or to 
      deploy rescue stents. This novel approach might be safely and effectively used in 
      patients undergoing endovascular treatment for anterior circulation aneurysms.
FAU - Ohshima, Tomotaka
AU  - Ohshima T
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.
FAU - Dash, Chinmaya
AU  - Dash C
AD  - Department of Neurosurgery, Fujita Health University Banbuntane Hotokukai Hospital, 
      Nagoya, Japan.
FAU - Belayev, Andrey
AU  - Belayev A
AD  - Department of Neurosurgery, Fujita Health University Banbuntane Hotokukai Hospital, 
      Nagoya, Japan.
FAU - Yamamoto, Taiki
AU  - Yamamoto T
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.
FAU - Goto, Shunsaku
AU  - Goto S
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.
FAU - Kato, Yoko
AU  - Kato Y
AD  - Department of Neurosurgery, Fujita Health University Banbuntane Hotokukai Hospital, 
      Nagoya, Japan.
LA  - eng
PT  - Journal Article
TA  - Nagoya J Med Sci
JT  - Nagoya journal of medical science
JID - 0412011
SB  - IM
MH  - Aged
MH  - Aneurysm, Ruptured/*therapy
MH  - Balloon Occlusion
MH  - Cerebral Angiography
MH  - Embolization, Therapeutic/adverse effects/*methods
MH  - Female
MH  - Humans
MH  - Intracranial Aneurysm/*therapy
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Treatment Outcome
PMC - PMC5719202
OTO - NOTNLM
OT  - *balloon guide catheter
OT  - *coil embolization
OT  - *intracranial aneurysms
EDAT- 2017/12/15 06:00
MHDA- 2018/12/12 06:00
CRDT- 2017/12/15 06:00
PHST- 2017/12/15 06:00 [entrez]
PHST- 2017/12/15 06:00 [pubmed]
PHST- 2018/12/12 06:00 [medline]
AID - 10.18999/nagjms.79.4.435 [doi]
PST - ppublish
SO  - Nagoya J Med Sci. 2017 Nov;79(4):435-441. doi: 10.18999/nagjms.79.4.435.

PMID- 31591997
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200122
IS  - 2005-3711 (Print)
IS  - 1598-7876 (Electronic)
IS  - 1225-8245 (Linking)
VI  - 63
IP  - 1
DP  - 2020 Jan
TI  - Role of Balloon Guide Catheter in Modern Endovascular Thrombectomy.
PG  - 14-25
LID - 10.3340/jkns.2019.0114 [doi]
AB  - Proximal flow control achieved with a balloon guide catheter (BGC) during 
      endovascular treatment of acute ischemic stroke is reviewed in this article. In 
      clinical practice, BGCs offer a multi-faceted approach for clot retrieval by 
      creating proximal flow arrest, reducing embolic burden, and shortening procedure 
      time. Evaluation of frontline thrombectomy procedures with BGCs revealed advantages 
      of combined use over the conventional guide catheter (CGC), notably in the 
      significant reduction of distal emboli to both the affected and previously 
      unaffected territories. Recently, new measures of early and complete reperfusion at 
      first thrombectomy pass have been identified as independent predictors of improved 
      outcomes, which were consistently demonstrated with use of BGC as a safe and 
      effective option to minimize number of passes during intervention. Prior randomized 
      controlled trials reported the positive correlation between BGC-treated patients and 
      a lower risk of mortality as well as shortened procedure time. While BGC use is more 
      common in stent retriever-mediated mechanical thrombectomy, preliminary data has 
      shown the potential benefit of device application during contact aspiration 
      thrombectomy to achieve successful recanalization. However, the question of which 
      major endovascular strategy reigns superior as a frontline remains to be answered. 
      Along with clinical case assessments, BGC performance during in-vitro simulation was 
      analyzed to further understand mechanisms for optimization of thrombectomy 
      technique.
FAU - Chueh, Ju-Yu
AU  - Chueh JY
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, MA, USA.
FAU - Kang, Dong-Hun
AU  - Kang DH
AD  - Department of Neurosurgery and Radiology, School of Medicine, Kyungpook National 
      University, Daegu, Korea.
FAU - Kim, Byung Moon
AU  - Kim BM
AD  - Department of Radiology, Severance Stroke Center, Severance Hospital, Yonsei 
      University College of Medicine, Seoul, Korea.
FAU - Gounis, Matthew J
AU  - Gounis MJ
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, MA, USA.
LA  - eng
PT  - Journal Article
DEP - 20191008
TA  - J Korean Neurosurg Soc
JT  - Journal of Korean Neurosurgical Society
JID - 101467054
PMC - PMC6952736
OTO - NOTNLM
OT  - Acute stroke
OT  - Balloon occlusion
OT  - Endovascular thrombectomy
OT  - Thrombectomy
COIS- JYC: Consultant for InNeuroCo and Stryker Neurovascular. MJG: Has been a consultant 
      on a fee-per-hour basis for Cerenovus, Imperative Care, Medtronic Neurovascular, 
      Mivi Neurosciences, Phenox, Route 92 Medical, Stryker Neurovascular; holds stock in 
      Imperative Care and Neurogami; and has received research support from the Research 
      support from the National Institutes of Health (NIH), the United States – Israel 
      Binational Science Foundation, Anaconda, Cerenovus, Cook Medical, Gentuity, 
      Imperative Care, InNeuroCo, Insera Therapeutics, Magneto, Microvention, Medtronic 
      Neurovascular, MIVI Neurosciences, Neuravi, Neurogami, Philips Healthcare, Rapid 
      Medical, Route 92 Medical, Stryker Neurovascular, Syntheon, and the Wyss Institute.
EDAT- 2019/10/09 06:00
MHDA- 2019/10/09 06:01
CRDT- 2019/10/09 06:00
PHST- 2019/05/09 00:00 [received]
PHST- 2019/06/21 00:00 [accepted]
PHST- 2019/10/09 06:00 [pubmed]
PHST- 2019/10/09 06:01 [medline]
PHST- 2019/10/09 06:00 [entrez]
AID - jkns.2019.0114 [pii]
AID - jkns-2019-0114 [pii]
AID - 10.3340/jkns.2019.0114 [doi]
PST - ppublish
SO  - J Korean Neurosurg Soc. 2020 Jan;63(1):14-25. doi: 10.3340/jkns.2019.0114. Epub 2019 
      Oct 8.

PMID- 30611184
OWN - NLM
STAT- In-Process
LR  - 20200226
IS  - 1092-0684 (Electronic)
IS  - 1092-0684 (Linking)
VI  - 46
IP  - Suppl_1
DP  - 2019 Jan 1
TI  - Nuances of carotid artery stenting under flow arrest with dual-balloon guide 
      catheter.
PG  - V4
LID - 2019.1.FocusVid.18417 [pii]
LID - 10.3171/2019.1.FocusVid.18417 [doi]
AB  - Cerebral protection device utilization during carotid artery stenting (CAS) has been 
      demonstrated to decrease the risk of perioperative stroke. The ProximAl Protection 
      with the MO.MA Device During CaRotid Stenting (ARMOUR) Trial had the lowest event 
      rates of any independently adjudicated study. In this video of two cases of severe 
      carotid artery stenosis, the authors present the nuances of the CAS procedure 
      utilizing a dual-balloon guide catheter device (MO.MA). This device has the benefit 
      of being in place before the lesion is crossed with any device, being able to arrest 
      flow while the atherosclerotic lesion is crossed, and aiding in protection from 
      distal emboli and stroke.The video can be found here: https://youtu.be/0o8DlC1n6_M.
FAU - Vercelli, Giovanni
AU  - Vercelli G
AD  - Departments of1Neurologic Surgery and.
FAU - Sorenson, Thomas J
AU  - Sorenson TJ
AD  - Departments of1Neurologic Surgery and.
AD  - 2School of Medicine, University of Minnesota, Minneapolis, Minnesota.
FAU - Giordan, Enrico
AU  - Giordan E
AD  - Departments of1Neurologic Surgery and.
FAU - Lanzino, Giuseppe
AU  - Lanzino G
AD  - Departments of1Neurologic Surgery and.
AD  - 3Radiology, Mayo Clinic, Rochester; and.
FAU - Rangel-Castilla, Leonardo
AU  - Rangel-Castilla L
AD  - Departments of1Neurologic Surgery and.
AD  - 3Radiology, Mayo Clinic, Rochester; and.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Neurosurg Focus
JT  - Neurosurgical focus
JID - 100896471
SB  - IM
OTO - NOTNLM
OT  - *carotid angioplasty
OT  - *carotid artery stenosis
OT  - *carotid artery stenting
OT  - *flow arrest
OT  - *stroke
OT  - *video
EDAT- 2019/01/06 06:00
MHDA- 2019/01/06 06:00
CRDT- 2019/01/06 06:00
PHST- 2018/09/03 00:00 [received]
PHST- 2018/11/14 00:00 [accepted]
PHST- 2019/01/06 06:00 [entrez]
PHST- 2019/01/06 06:00 [pubmed]
PHST- 2019/01/06 06:00 [medline]
AID - 2019.1.FocusVid.18417 [pii]
AID - 10.3171/2019.1.FocusVid.18417 [doi]
PST - ppublish
SO  - Neurosurg Focus. 2019 Jan 1;46(Suppl_1):V4. doi: 10.3171/2019.1.FocusVid.18417.

PMID- 31409062
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200225
IS  - 2093-9043 (Print)
IS  - 2233-6273 (Electronic)
IS  - 2093-9043 (Linking)
VI  - 14
IP  - 2
DP  - 2019 Sep
TI  - Recent Trend for Endovascular Treatment in Patients with Acute Ischemic Stroke: 
      Balloon Guide Catheter.
PG  - 142-143
LID - 10.5469/neuroint.2019.00136 [doi]
FAU - Suh, Chong Hyun
AU  - Suh CH
AD  - Department of Radiology and Research Institute of Radiology, Asan Medical Center, 
      University of Ulsan College of Medicine, Seoul, Korea.
FAU - Lee, Young-Jun
AU  - Lee YJ
AD  - Department of Radiology, Hanyang University Hospital, Hanyang University College of 
      Medicine, Seoul, Korea.
LA  - eng
PT  - Journal Article
DEP - 20190816
TA  - Neurointervention
JT  - Neurointervention
JID - 101561462
PMC - PMC6736498
EDAT- 2019/08/15 06:00
MHDA- 2019/08/15 06:01
CRDT- 2019/08/15 06:00
PHST- 2019/06/20 00:00 [received]
PHST- 2019/08/12 00:00 [accepted]
PHST- 2019/08/15 06:00 [pubmed]
PHST- 2019/08/15 06:01 [medline]
PHST- 2019/08/15 06:00 [entrez]
AID - neuroint.2019.00136 [pii]
AID - neuroint-2019-00136 [pii]
AID - 10.5469/neuroint.2019.00136 [doi]
PST - ppublish
SO  - Neurointervention. 2019 Sep;14(2):142-143. doi: 10.5469/neuroint.2019.00136. Epub 
      2019 Aug 16.

PMID- 30997860
OWN - NLM
STAT- MEDLINE
DCOM- 20200227
LR  - 20200227
IS  - 2385-2011 (Electronic)
IS  - 1591-0199 (Print)
IS  - 1591-0199 (Linking)
VI  - 25
IP  - 5
DP  - 2019 Oct
TI  - Intracranial mechanical thrombectomy using a proximal balloon guide catheter via a 
      transradial access.
PG  - 508-510
LID - 10.1177/1591019919844850 [doi]
AB  - We present a description of a successful recanalization of an intracranial vessel 
      occlusion by stent retriever-based mechanical thrombectomy with a proximal balloon 
      guide catheter introduced via a transradial access. Therefore, we used the radial 
      artery itself as a natural sheath, as the introduction of a balloon guide catheter 
      would not have been possible through a common radial sheath.
FAU - Maus, Volker
AU  - Maus V
AUID- ORCID: 0000-0001-5097-2631
AD  - Department of Neuroradiology, University Medical Center Goettingen, Goettingen, 
      Germany.
FAU - Styczen, Hanna
AU  - Styczen H
AUID- ORCID: 0000-0002-9623-4156
AD  - Department of Neuroradiology, University Medical Center Goettingen, Goettingen, 
      Germany.
FAU - Psychogios, Marios-Nikos
AU  - Psychogios MN
AD  - Department of Neuroradiology, University Medical Center Goettingen, Goettingen, 
      Germany.
AD  - Department of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University 
      Hospital Basel, Basel, Switzerland.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20190418
TA  - Interv Neuroradiol
JT  - Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical 
      procedures and related neurosciences
JID - 9602695
SB  - IM
MH  - Aged
MH  - Brain Ischemia/diagnostic imaging/surgery
MH  - Catheterization, Peripheral/*methods
MH  - Computed Tomography Angiography
MH  - Humans
MH  - Male
MH  - *Radial Artery
MH  - Stents
MH  - Stroke/diagnostic imaging/surgery
MH  - Thrombectomy/*methods
MH  - Treatment Outcome
PMC - PMC6777110
OTO - NOTNLM
OT  - Ischaemic stroke
OT  - balloon guide catheter
OT  - mechanical thrombectomy
OT  - transradial
EDAT- 2019/04/19 06:00
MHDA- 2020/02/28 06:00
PMCR- 2020/10/01
CRDT- 2019/04/19 06:00
PHST- 2020/10/01 00:00 [pmc-release]
PHST- 2019/04/19 06:00 [pubmed]
PHST- 2020/02/28 06:00 [medline]
PHST- 2019/04/19 06:00 [entrez]
AID - 10.1177_1591019919844850 [pii]
AID - 10.1177/1591019919844850 [doi]
PST - ppublish
SO  - Interv Neuroradiol. 2019 Oct;25(5):508-510. doi: 10.1177/1591019919844850. Epub 2019 
      Apr 18.

PMID- 30851472
OWN - NLM
STAT- MEDLINE
DCOM- 20200116
LR  - 20200116
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 126
DP  - 2019 Jun
TI  - Experience of the New FlowGate(2) Device as a Balloon Guide Catheter for Ischemic 
      Stroke Intervention.
PG  - e736-e742
LID - S1878-8750(19)30563-7 [pii]
LID - 10.1016/j.wneu.2019.02.140 [doi]
AB  - BACKGROUND: We report the experience of the FlowGate(2) (FG2) as a new balloon guide 
      catheter in endovascular stroke intervention. METHODS: We evaluated the various 
      outcomes and complications of patients with intracranial large artery occlusion 
      undergoing endovascular stroke intervention with FG2 at our center. Baseline 
      characteristics (failure rate of device application, sex, age, risk factors, 
      arterial occlusion sites, and time intervals) were reviewed. Outcomes were evaluated 
      according to National Institutes of Health Stroke Scale score, modified Rankin Scale 
      (mRS) score, number of stent passages required, and Thrombolysis in Cerebral 
      Infarction score. The incidence of hemorrhage, vessel damage, distal emboli, and 
      mortality rate were evaluated as indicators of complications. RESULTS: Overall, 70 
      patients were enrolled, except the 2 patients with application failure of FG2. 
      Seventy patients with a median age of 69 years were treated with FG2. Arterial 
      occlusion involved the M1 (50%) and M2 (14.3%) segments, internal carotid artery 
      (25.7%), and posterior circulation (10%). Median value of mRS at 90 days was 2.8, 
      and 37 patients (52.8%) had a mRS score ≤2. The recanalization rate in patients with 
      a Thrombolysis in Cerebral Infarction score of 2b or 3 was 91.4%. The hemorrhage 
      rate was 5.7%, but none were symptomatic. In terms of complications, distal emboli 
      occurred in 4.3% of cases. CONCLUSIONS: Endovascular stroke intervention with the 
      FG2 is safe and effective with good accessibility and less occurrence of distal 
      emboli. Its trackability, stability, and luminal size make the FG2 suitable for 
      stroke intervention.
CI  - Copyright © 2019 Elsevier Inc. All rights reserved.
FAU - Yi, Ho Jun
AU  - Yi HJ
AD  - Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Republic of Korea.
FAU - Sung, Jae Hoon
AU  - Sung JH
AD  - Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Republic of Korea. Electronic address: 
      jaehoonsung@gmail.com.
FAU - Lee, Min Hyung
AU  - Lee MH
AD  - Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Republic of Korea.
FAU - Lee, Dong Hoon
AU  - Lee DH
AD  - Department of Neurosurgery, St. Vincent's Hospital, College of Medicine, The 
      Catholic University of Korea, Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
DEP - 20190306
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Ischemia/*surgery
MH  - *Catheters
MH  - Endovascular Procedures/*instrumentation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Stroke/*surgery
MH  - Thrombectomy/*instrumentation
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Balloon guide catheter
OT  - Intervention
OT  - Stents
OT  - Stroke
OT  - Thrombectomy
EDAT- 2019/03/10 06:00
MHDA- 2020/01/17 06:00
CRDT- 2019/03/10 06:00
PHST- 2018/12/28 00:00 [received]
PHST- 2019/02/12 00:00 [revised]
PHST- 2019/02/13 00:00 [accepted]
PHST- 2019/03/10 06:00 [pubmed]
PHST- 2020/01/17 06:00 [medline]
PHST- 2019/03/10 06:00 [entrez]
AID - S1878-8750(19)30563-7 [pii]
AID - 10.1016/j.wneu.2019.02.140 [doi]
PST - ppublish
SO  - World Neurosurg. 2019 Jun;126:e736-e742. doi: 10.1016/j.wneu.2019.02.140. Epub 2019 
      Mar 6.

PMID- 29378450
OWN - NLM
STAT- MEDLINE
DCOM- 20181001
LR  - 20190610
IS  - 2385-2011 (Electronic)
IS  - 1591-0199 (Print)
IS  - 1591-0199 (Linking)
VI  - 24
IP  - 3
DP  - 2018 Jun
TI  - Simple aspiration with balloon catheter technique (simple ABC technique) against 
      proximal internal carotid artery occlusion in cases of cardiogenic cerebral 
      embolism.
PG  - 317-321
LID - 10.1177/1591019917753823 [doi]
AB  - Background In cases of acute ischemic stroke, manual aspiration of the thrombus is 
      commonly performed with a balloon guiding catheter placed in the cervical segment of 
      the internal carotid artery (ICA). However, most manual aspirations using a balloon 
      guiding catheter are combined with inner catheters, as in the direct aspiration 
      first pass technique (ADAPT). We experienced some cases of acute ischemic stroke 
      with proximal ICA occlusion due to cardiogenic thrombus where we obtained sufficient 
      recanalization by simple manual aspiration from inflated Optimo 9F balloon catheters 
      (Tokai Medical Products, Japan) placed in the origin of the cervical segment of the 
      ICA without any inner catheter or stent retriever. We perform by preference this 
      procedure, named the simple Aspiration with Balloon Catheter (simple ABC) technique. 
      Herein, we report two recent cases and discuss this procedure. Case presentation 
      Case 1: An 80-year-old man with paroxysmal atrial fibrillation developed left ICA 
      occlusion. We performed the simple ABC technique and obtained a large amount of dark 
      red and white thrombus. Puncture-to-reperfusion time was 14 minutes with 
      Thrombolysis in Cerebral Infarction (TICI) grade 3. Case 2: A 69-year-old man with 
      chronic atrial fibrillation developed left internal carotid occlusion. We performed 
      the simple ABC technique and obtained a large amount of dark red thrombus. 
      Puncture-to-reperfusion time was 15 minutes with TICI grade 2b. Conclusion The 
      simple ABC technique is useful to deal with a large amount of thrombus, shortens 
      procedure time, enables less invasive thrombectomy, and can shift immediately to 
      subsequent procedures such as delivering a stent retriever or ADAPT.
FAU - Okamura, Akitake
AU  - Okamura A
AD  - Department of Neurosurgery, Hiroshima General Hospital, Hiroshima, Japan.
FAU - Kuroki, Kazuhiko
AU  - Kuroki K
AD  - Department of Neurosurgery, Hiroshima General Hospital, Hiroshima, Japan.
FAU - Shinagawa, Katsuhiro
AU  - Shinagawa K
AD  - Department of Neurosurgery, Hiroshima General Hospital, Hiroshima, Japan.
FAU - Yamada, Naoto
AU  - Yamada N
AD  - Department of Neurosurgery, Hiroshima General Hospital, Hiroshima, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20180129
TA  - Interv Neuroradiol
JT  - Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical 
      procedures and related neurosciences
JID - 9602695
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/*complications
MH  - Brain Ischemia/*etiology/*surgery
MH  - *Carotid Artery, Internal
MH  - Endovascular Procedures/*methods
MH  - Humans
MH  - Intracranial Embolism/*etiology/*surgery
MH  - Male
MH  - Neuroimaging
MH  - Stroke/*etiology/*surgery
MH  - Suction/methods
PMC - PMC5967180
OTO - NOTNLM
OT  - Acute ischemic stroke
OT  - balloon guide catheter
OT  - cardiogenic cerebral embolism
OT  - manual aspiration
OT  - simple ABC technique
EDAT- 2018/01/31 06:00
MHDA- 2018/10/03 06:00
CRDT- 2018/01/31 06:00
PHST- 2018/01/31 06:00 [pubmed]
PHST- 2018/10/03 06:00 [medline]
PHST- 2018/01/31 06:00 [entrez]
AID - 10.1177_1591019917753823 [pii]
AID - 10.1177/1591019917753823 [doi]
PST - ppublish
SO  - Interv Neuroradiol. 2018 Jun;24(3):317-321. doi: 10.1177/1591019917753823. Epub 2018 
      Jan 29.

PMID- 31514211
OWN - NLM
STAT- In-Data-Review
LR  - 20200220
IS  - 1438-9010 (Electronic)
IS  - 1438-9010 (Linking)
VI  - 192
IP  - 3
DP  - 2020 Mar
TI  - Influence of Thrombus Composition on Thrombectomy: ADAPT vs. Balloon Guide Catheter 
      and Stent Retriever in a Flow Model.
PG  - 257-263
LID - 10.1055/a-0998-4246 [doi]
AB  - PURPOSE:  A first-pass, direct aspiration technique and stent retrieval with a 
      balloon guide catheter represent advanced thrombectomy techniques that are 
      increasingly being used in the clinical routine. The purpose of this experimental 
      study was to evaluate whether the techniques' effectiveness depended on the clot 
      composition and to visualize the interaction between the devices and the clot. 
      MATERIALS AND METHODS:  Erythrocyte-rich (red) and fibrin-rich (white) clots were 
      placed into the M1-segment of the middle cerebral artery in a transparent vascular 
      phantom with physiological architecture. Physiological hemodynamic conditions were 
      maintained with a programmable pump. On the one hand direct aspiration with a 5F 
      aspiration catheter (ADAPT) and on the other hand stent retrieval with a balloon 
      guide catheter (flow arrest/reversal) was performed. The experiments were made under 
      direct visual control to observe the interaction between the devices and the clot. 
      The primary end points were the number of passes/maneuvers and the occurrence of 
      distal emboli and emboli in a new territory (anterior cerebral artery), until full 
      recanalization was achieved. The experiment was filmed with a full high-definition 
      camera identifying emboli. RESULTS:  Six experiments were conducted for each 
      technique and clot model. Red clots were retrieved by ADAPT with fewer passes and 
      distal emboli, and could usually be aspirated directly at the occlusion site. White 
      clots clogged the tip of the 5F aspiration catheter in every experiment. The 
      catheter had to be pulled back into the long sheath in the cervical internal carotid 
      artery, producing distal emboli. White clots were retrieved by the stent retriever 
      and balloon guide catheter with fewer distal emboli. There was no difference in the 
      number of passes. The stent-thrombus interaction was superficial in both clot 
      models. Successful retrieval was granted by the flow arrest and proximal 
      aspiration/flow reversal. One embolus in a new territory developed when using each 
      technique in white clots. CONCLUSION:  This experimental study showed that the 
      efficacy of advanced thrombectomy techniques might depend on clot composition. 
      Identifying the right technique for the right clot might improve the results of 
      thrombectomy. In a clinical setting the thrombus morphology in non-enhanced CT could 
      be used as a marker for patient selection. KEY POINTS:   · The efficacy of 
      thrombectomy seems to depend on thrombus composition.. · ADAPT might be more 
      effective for rbc-rich clots.. · Thrombectomy with BGC might be more effective for 
      fibrin-rich clots.. CITATION FORMAT: · Madjidyar J, Pineda Vidal L, Larsen N et al. 
      Influence of Thrombus Composition on Thrombectomy: ADAPT vs. Balloon Guide Catheter 
      and Stent Retriever in a Flow Model. Fortschr Röntgenstr 2020; 192: 257 - 263.
CI  - © Georg Thieme Verlag KG Stuttgart · New York.
FAU - Madjidyar, Jawid
AU  - Madjidyar J
AD  - Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany.
FAU - Pineda Vidal, Lorena
AU  - Pineda Vidal L
AD  - Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany.
FAU - Larsen, Naomi
AU  - Larsen N
AD  - Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany.
FAU - Jansen, Olav
AU  - Jansen O
AD  - Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany.
LA  - eng
PT  - Journal Article
TT  - Einfluss der Thrombus-Zusammensetzung auf die Thrombektomie: ADAPT gegen 
      Balloon-Guide-Catheter und Stent-Retriever in einem Flussmodell.
DEP - 20190912
PL  - Germany
TA  - Rofo
JT  - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
JID - 7507497
SB  - IM
COIS- The authors declare that they have no conflict of interest.
EDAT- 2019/09/13 06:00
MHDA- 2019/09/13 06:00
CRDT- 2019/09/13 06:00
PHST- 2019/09/13 06:00 [pubmed]
PHST- 2019/09/13 06:00 [medline]
PHST- 2019/09/13 06:00 [entrez]
AID - 10.1055/a-0998-4246 [doi]
PST - ppublish
SO  - Rofo. 2020 Mar;192(3):257-263. doi: 10.1055/a-0998-4246. Epub 2019 Sep 12.

PMID- 26801392
OWN - NLM
STAT- MEDLINE
DCOM- 20170516
LR  - 20181113
IS  - 1869-1447 (Electronic)
IS  - 1869-1439 (Linking)
VI  - 26
IP  - 3
DP  - 2016 Sep
TI  - Balloon Guide Catheter in Complex Anterior Circulation Mechanical Thrombectomy: 
      Beyond Proximal Occlusion and Flow Reversal.
PG  - 369-73
LID - 10.1007/s00062-016-0498-z [doi]
FAU - Demerath, T
AU  - Demerath T
AD  - Department of Neuroradiology, Neurocenter, University Hospital Freiburg, Breisacher 
      Strasse 64, 79106, Freiburg, Germany.
FAU - Reinhard, M
AU  - Reinhard M
AD  - Department of Neurology, Neurocenter, University Hospital Freiburg, Freiburg, 
      Germany.
FAU - Elsheikh, S
AU  - Elsheikh S
AD  - Department of Neuroradiology, Neurocenter, University Hospital Freiburg, Breisacher 
      Strasse 64, 79106, Freiburg, Germany.
FAU - Keuler, A
AU  - Keuler A
AD  - Department of Radiology, University Hospital of Cologne, Cologne, Germany.
FAU - Urbach, H
AU  - Urbach H
AD  - Department of Neuroradiology, Neurocenter, University Hospital Freiburg, Breisacher 
      Strasse 64, 79106, Freiburg, Germany.
FAU - Meckel, S
AU  - Meckel S
AD  - Department of Neuroradiology, Neurocenter, University Hospital Freiburg, Breisacher 
      Strasse 64, 79106, Freiburg, Germany. stephanmeckel@gmail.com.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20160122
PL  - Germany
TA  - Clin Neuroradiol
JT  - Clinical neuroradiology
JID - 101526693
SB  - IM
MH  - Aged
MH  - Balloon Occlusion/*instrumentation/*methods
MH  - Brain Infarction/*diagnostic imaging/*surgery
MH  - Cerebral Angiography/methods
MH  - Equipment Design
MH  - Equipment Failure Analysis
MH  - Female
MH  - Humans
MH  - Mechanical Thrombolysis/*instrumentation/*methods
MH  - Treatment Outcome
EDAT- 2016/01/24 06:00
MHDA- 2017/05/17 06:00
CRDT- 2016/01/24 06:00
PHST- 2015/10/28 00:00 [received]
PHST- 2016/01/08 00:00 [accepted]
PHST- 2016/01/24 06:00 [entrez]
PHST- 2016/01/24 06:00 [pubmed]
PHST- 2017/05/17 06:00 [medline]
AID - 10.1007/s00062-016-0498-z [pii]
AID - 10.1007/s00062-016-0498-z [doi]
PST - ppublish
SO  - Clin Neuroradiol. 2016 Sep;26(3):369-73. doi: 10.1007/s00062-016-0498-z. Epub 2016 
      Jan 22.

PMID- 28712895
OWN - NLM
STAT- MEDLINE
DCOM- 20171226
LR  - 20171226
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 106
DP  - 2017 Oct
TI  - Parent and Child Balloon Technique for Navigating Guide Catheters During 
      Neurointerventions.
PG  - 409-412
LID - S1878-8750(17)31130-0 [pii]
LID - 10.1016/j.wneu.2017.07.030 [doi]
AB  - BACKGROUND: The stabilization of a guide catheter is an important factor for 
      performing successful neurointerventional procedures. We present our technique for 
      navigating guide catheters using parent and child balloons. METHODS: In 9 patients 
      with severe atherosclerosis or anatomic variations such as a bovine arch, 8-9-F 
      balloon-mounted guide catheters were navigated using balloon-attached guidewires. 
      Both balloons were used complementarily for flow navigation and vessel fixation at 
      the appropriate positions and times. RESULTS: In all cases, the balloon guide 
      catheter could be inserted up to the required positions, and the procedures were 
      completed without any complications. CONCLUSIONS: The parent and child balloon 
      technique is useful for inserting guide catheters in hostile vascular anatomies.
CI  - Copyright © 2017 Elsevier Inc. All rights reserved.
FAU - Ohshima, Tomotaka
AU  - Ohshima T
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan. 
      Electronic address: tmtkoh@gmail.com.
FAU - Ishikawa, Kojiro
AU  - Ishikawa K
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.
FAU - Goto, Shunsaku
AU  - Goto S
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.
FAU - Yamamoto, Taiki
AU  - Yamamoto T
AD  - Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.
LA  - eng
PT  - Journal Article
DEP - 20170713
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Balloon Occlusion/*methods
MH  - Carotid Arteries/*diagnostic imaging/surgery
MH  - Catheterization/*methods
MH  - Female
MH  - Femoral Artery/*diagnostic imaging/surgery
MH  - Humans
MH  - Male
MH  - Neuronavigation/*methods
OTO - NOTNLM
OT  - Balloon
OT  - Endovascular treatment
OT  - Guide catheter
OT  - Navigation
EDAT- 2017/07/18 06:00
MHDA- 2017/12/27 06:00
CRDT- 2017/07/18 06:00
PHST- 2017/05/18 00:00 [received]
PHST- 2017/07/03 00:00 [revised]
PHST- 2017/07/06 00:00 [accepted]
PHST- 2017/07/18 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
PHST- 2017/07/18 06:00 [entrez]
AID - S1878-8750(17)31130-0 [pii]
AID - 10.1016/j.wneu.2017.07.030 [doi]
PST - ppublish
SO  - World Neurosurg. 2017 Oct;106:409-412. doi: 10.1016/j.wneu.2017.07.030. Epub 2017 
      Jul 13.

PMID- 27987034
OWN - NLM
STAT- MEDLINE
DCOM- 20170620
LR  - 20181113
IS  - 1437-2320 (Electronic)
IS  - 0344-5607 (Linking)
VI  - 40
IP  - 2
DP  - 2017 Apr
TI  - Retrograde suction decompression of a large internal carotid aneurysm using a 
      balloon guide catheter combined with a blood-returning circuit and STA-MCA bypass: a 
      technical note.
PG  - 351-355
LID - 10.1007/s10143-016-0808-6 [doi]
AB  - It is difficult to treat large internal carotid aneurysms with simple surgical 
      clipping. Here, we present a retrograde suction decompression (RSD) procedure for 
      large internal carotid aneurysms using a balloon guide catheter combined with a 
      blood-returning circuit and a superficial temporal artery to middle cerebral artery 
      (STA-MCA) bypass.All patients underwent an STA-MCA bypass before the temporary 
      occlusion of the internal carotid artery (ICA). A 6-French sheath was inserted into 
      the common carotid artery (CCA), and a 6-French Patrive balloon catheter was placed 
      into the ICA 5 cm past the bifurcation. Aneurysm exposure was obtained; temporary 
      clips were placed on the proximal M1, A1, and posterior communicating (Pcom) 
      segments; and an extension tube was then connected to the balloon catheter. A 
      three-way stopcock was placed, and aspiration was performed through the device to 
      collapse the aneurysm. The aspirated blood was returned to a venous line with an 
      added heparin to prevent anemia after aspiration. During the decompression, the 
      blood flow to the cortical area was supplied through the STA-MCA bypass. After the 
      aneurysm collapse, the surgeon carefully dissected the perforating artery from the 
      aneurysm dome or neck, and permanent clips were then placed on the aneurysm neck. 
      Our procedure has several advantages, such as STA-MCA bypass without external 
      carotid artery occlusion for preventing ischemic complications of the cortical area, 
      anemia may be avoided because of the return of the aspirated blood, and a hybrid 
      operation room is not required to perform this method.
FAU - Matano, Fumihiro
AU  - Matano F
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan. s00-078@nms.ac.jp.
FAU - Mizunari, Takayuki
AU  - Mizunari T
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan.
FAU - Kominami, Shushi
AU  - Kominami S
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan.
FAU - Suzuki, Masanori
AU  - Suzuki M
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan.
FAU - Fujiki, Yu
AU  - Fujiki Y
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan.
FAU - Kubota, Asami
AU  - Kubota A
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan.
FAU - Kobayashi, Shiro
AU  - Kobayashi S
AD  - Department of Neurosurgery, Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 
      270-1694, Japan.
FAU - Murai, Yasuo
AU  - Murai Y
AD  - Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.
FAU - Morita, Akio
AU  - Morita A
AD  - Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20161216
PL  - Germany
TA  - Neurosurg Rev
JT  - Neurosurgical review
JID - 7908181
SB  - IM
MH  - Anastomosis, Surgical/instrumentation/methods
MH  - Aneurysm/diagnostic imaging/surgery
MH  - Aneurysm, Ruptured/diagnostic imaging/*surgery
MH  - Carotid Artery, Internal/diagnostic imaging/*surgery
MH  - Cerebral Revascularization/instrumentation/methods
MH  - Decompression, Surgical/instrumentation/*methods
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Middle Cerebral Artery/diagnostic imaging/*surgery
MH  - Suction
MH  - Surgical Stapling
MH  - Temporal Arteries/diagnostic imaging/*surgery
OTO - NOTNLM
OT  - Aneurysm
OT  - Balloon catheter
OT  - Suction decompression
EDAT- 2016/12/18 06:00
MHDA- 2017/06/21 06:00
CRDT- 2016/12/18 06:00
PHST- 2016/10/17 00:00 [received]
PHST- 2016/12/09 00:00 [accepted]
PHST- 2016/11/19 00:00 [revised]
PHST- 2016/12/18 06:00 [pubmed]
PHST- 2017/06/21 06:00 [medline]
PHST- 2016/12/18 06:00 [entrez]
AID - 10.1007/s10143-016-0808-6 [pii]
AID - 10.1007/s10143-016-0808-6 [doi]
PST - ppublish
SO  - Neurosurg Rev. 2017 Apr;40(2):351-355. doi: 10.1007/s10143-016-0808-6. Epub 2016 Dec 
      16.

PMID- 30711506
OWN - NLM
STAT- MEDLINE
DCOM- 20190805
LR  - 20190805
IS  - 1615-5947 (Electronic)
IS  - 0890-5096 (Linking)
VI  - 58
DP  - 2019 Jul
TI  - Endovascular Treatment with Two Overlapping Micromesh-Covered Stents and Balloon 
      Guide Catheter for Symptomatic Carotid Pseudoaneurysm Ten Years after Eversion 
      Endarterectomy.
PG  - 379.e9-379.e13
LID - S0890-5096(19)30048-2 [pii]
LID - 10.1016/j.avsg.2018.10.026 [doi]
AB  - Pseudoaneurysm is a rare complication after carotid endarterectomy. Herein, we 
      report a successful endovascular exclusion of a symptomatic carotid pseudoaneurysm 
      occurred ten years after an eversion carotid endarterectomy by means of 2 
      overlapping micromesh stents (InspireMD C-Guard™) and balloon guide catheter 
      (FlowGate(2) Balloon Guide Catheter) used as a proximal protection device.
CI  - Copyright © 2019 Elsevier Inc. All rights reserved.
FAU - Siani, Andrea
AU  - Siani A
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy. Electronic address: andreasiani@yahoo.it.
FAU - Castrucci, Tommaso
AU  - Castrucci T
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
FAU - Accrocca, Federico
AU  - Accrocca F
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
FAU - Ianni, Giulia
AU  - Ianni G
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
FAU - Corona, Stefano
AU  - Corona S
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
FAU - De Vivo, Gennaro
AU  - De Vivo G
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
FAU - Smedile, Gianluca
AU  - Smedile G
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
FAU - Bartoli, Stefano
AU  - Bartoli S
AD  - Unit of Vascular, Endovascular and Emergency Vascular Surgery, "S. Eugenio" 
      Hospital, ASL-RM 2 Rome, Italy.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20190131
PL  - Netherlands
TA  - Ann Vasc Surg
JT  - Annals of vascular surgery
JID - 8703941
MH  - Aged
MH  - Aneurysm, False/diagnostic imaging/etiology/*therapy
MH  - Angioplasty, Balloon/*instrumentation
MH  - Carotid Artery Diseases/*surgery
MH  - Computed Tomography Angiography
MH  - *Embolic Protection Devices
MH  - Endarterectomy, Carotid/*adverse effects
MH  - Humans
MH  - Male
MH  - Prosthesis Design
MH  - *Stents
MH  - *Surgical Mesh
MH  - Treatment Outcome
EDAT- 2019/02/04 06:00
MHDA- 2019/08/06 06:00
CRDT- 2019/02/04 06:00
PHST- 2018/08/20 00:00 [received]
PHST- 2018/10/09 00:00 [revised]
PHST- 2018/10/10 00:00 [accepted]
PHST- 2019/02/04 06:00 [pubmed]
PHST- 2019/08/06 06:00 [medline]
PHST- 2019/02/04 06:00 [entrez]
AID - S0890-5096(19)30048-2 [pii]
AID - 10.1016/j.avsg.2018.10.026 [doi]
PST - ppublish
SO  - Ann Vasc Surg. 2019 Jul;58:379.e9-379.e13. doi: 10.1016/j.avsg.2018.10.026. Epub 
      2019 Jan 31.

PMID- 24302483
OWN - NLM
STAT- MEDLINE
DCOM- 20140220
LR  - 20161122
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 45
IP  - 1
DP  - 2014 Jan
TI  - Balloon guide catheter improves revascularization and clinical outcomes with the 
      Solitaire device: analysis of the North American Solitaire Acute Stroke Registry.
PG  - 141-5
LID - 10.1161/STROKEAHA.113.002407 [doi]
AB  - BACKGROUND AND PURPOSE: Efficient and timely recanalization is an important goal in 
      acute stroke endovascular therapy. Several studies demonstrated improved 
      recanalization and clinical outcomes with the stent retriever devices compared with 
      the Merci device. The goal of this study was to evaluate the role of the balloon 
      guide catheter (BGC) and recanalization success in a substudy of the North American 
      Solitaire Acute Stroke (NASA) registry. METHODS: The investigator-initiated NASA 
      registry recruited 24 clinical sites within North America to submit demographic, 
      clinical, site-adjudicated angiographic, and clinical outcome data on consecutive 
      patients treated with the Solitaire Flow Restoration device. BGC use was at the 
      discretion of the treating physicians. RESULTS: There were 354 patients included in 
      the NASA registry. BGC data were reported in 338 of 354 patients in this 
      subanalysis, of which 149 (44%) had placement of a BGC. Mean age was 67.3±15.2 
      years, and median National Institutes of Health Stroke Scale score was 18. Patients 
      with BGC had more hypertension (82.4% versus 72.5%; P=0.05), atrial fibrillation 
      (50.3% versus 32.8%; P=0.001), and were more commonly administered tissue 
      plasminogen activator (51.6% versus 38.8%; P=0.02) compared with patients without 
      BGC. Time from symptom onset to groin puncture and number of passes were similar 
      between the 2 groups. Procedure time was shorter in patients with BGC (120±28.5 
      versus 161±35.6 minutes; P=0.02), and less adjunctive therapy was used in patients 
      with BGC (20% versus 28.6%; P=0.05). Thrombolysis in cerebral infarction 3 
      reperfusion scores were higher in patients with BGC (53.7% versus 32.5%; P<0.001). 
      Distal emboli and emboli in new territory were similar between the 2 groups. 
      Discharge National Institutes of Health Stroke Scale score (mean, 12±14.5 versus 
      17.5±16; P=0.002) and good clinical outcome at 3 months were superior in patients 
      with BGC compared with patients without (51.6% versus 35.8%; P=0.02). Multivariate 
      analysis demonstrated that the use of BGC was an independent predictor of good 
      clinical outcome (odds ratio, 2.5; 95% confidence interval, 1.2-4.9). CONCLUSIONS: 
      Use of a BGC with the Solitaire Flow Restoration device resulted in superior 
      revascularization results, faster procedure times, decreased need for adjunctive 
      therapy, and improved clinical outcome.
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - From the Departments of Neurology (T.N.N., H.M.), Neurosurgery (T.N.N.), and 
      Radiology (T.N.N., H.M., A.M.N.), Boston University School of Medicine, MA; Alexian 
      Brothers Medical Center, Elk Grove Village, IL (T.M., F.A.M.); Departments of 
      Neurosurgery (O.O.Z.), Neurology (A.C.C., M.A.I., O.O.Z.), and Radiology (O.O.Z.), 
      Medical College of Wisconsin, Milwaukee; Department of Neurology, Emory University 
      School of Medicine, Atlanta, GA (R.G., C.-H.J.S., R.G.N.); St. Luke's Neuroscience 
      Institute, Kansas City, MO (C.O.M., W.E.H.); Department of Neurology, Delray Medical 
      Center, Delray Beach, FL (N.M.-K.); California Pacific Medical Center, San Francisco 
      (J.D.E.); Division of Interventional Neuroradiology, Baptist Cardiac and Vascular 
      Institute, Miami, FL (I.L., G.D.); Oregon Health and Sciences, Portland (H.B.); 
      Department of Neurology, Wayne State University School of Medicine, Detroit, MI 
      (A.X.); Department of Radiology, West Virginia University Hospital, Morgantown 
      (A.T.R.); Department of Neurology, Neurosurgery, and Radiology, Vanderbilt 
      University Medical Center, Nashville, TN (M.T.F.); Department of Neurosurgery, 
      Presence Saint Joseph Medical Center, Joliet, IL (A.B.); Desert Regional Medical 
      Center, Palm Springs, CA (M.T.); University of Kansas Medical Center, Kansas City 
      (M.G.A.); Texas Stroke Institute, Dallas Fort-Worth Metroplex (V.J.); Baylor College 
      of Medicine, Houston, TX (H.S.); Departments of Radiology and Neurology, UT 
      Southwestern Medical Center, Dallas, TX (R.N.); Department of Radiology, Division of 
      Diagnostic and Interventional Neuroradiology, Massachusetts General Hospital, Boston 
      (A.J.Y.); Department of Neurology, University of Louisville Medical School, KY 
      (A.-A.C.); University of Texas, Houston (P.R.C.); Department of Neurosurgery, 
      Methodist Neurological Institute, Houston, TX (G.W.B.); Tenet Health Florida, 
      Hialeah (R.K.); and University of Missouri, Columbia (A.N.).
FAU - Malisch, Timothy
AU  - Malisch T
FAU - Castonguay, Alicia C
AU  - Castonguay AC
FAU - Gupta, Rishi
AU  - Gupta R
FAU - Sun, Chung-Huan J
AU  - Sun CH
FAU - Martin, Coleman O
AU  - Martin CO
FAU - Holloway, William E
AU  - Holloway WE
FAU - Mueller-Kronast, Nils
AU  - Mueller-Kronast N
FAU - English, Joey D
AU  - English JD
FAU - Linfante, Italo
AU  - Linfante I
FAU - Dabus, Guilherme
AU  - Dabus G
FAU - Marden, Franklin A
AU  - Marden FA
FAU - Bozorgchami, Hormozd
AU  - Bozorgchami H
FAU - Xavier, Andrew
AU  - Xavier A
FAU - Rai, Ansaar T
AU  - Rai AT
FAU - Froehler, Michael T
AU  - Froehler MT
FAU - Badruddin, Aamir
AU  - Badruddin A
FAU - Taqi, Muhammad
AU  - Taqi M
FAU - Abraham, Michael G
AU  - Abraham MG
FAU - Janardhan, Vallabh
AU  - Janardhan V
FAU - Shaltoni, Hashem
AU  - Shaltoni H
FAU - Novakovic, Roberta
AU  - Novakovic R
FAU - Yoo, Albert J
AU  - Yoo AJ
FAU - Abou-Chebl, Alex
AU  - Abou-Chebl A
FAU - Chen, Peng R
AU  - Chen PR
FAU - Britz, Gavin W
AU  - Britz GW
FAU - Kaushal, Ritesh
AU  - Kaushal R
FAU - Nanda, Ashish
AU  - Nanda A
FAU - Issa, Mohammad A
AU  - Issa MA
FAU - Masoud, Hesham
AU  - Masoud H
FAU - Nogueira, Raul G
AU  - Nogueira RG
FAU - Norbash, Alexander M
AU  - Norbash AM
FAU - Zaidat, Osama O
AU  - Zaidat OO
LA  - eng
PT  - Journal Article
DEP - 20131203
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
CIN - Stroke. 2014 May;45(5):e86. PMID: 24627111
CIN - Stroke. 2014 May;45(5):e85. PMID: 24627115
MH  - Aged
MH  - Catheterization, Central Venous/*methods
MH  - Cerebral Angiography
MH  - Cerebral Revascularization/*methods
MH  - Cerebrovascular Circulation/physiology
MH  - Endovascular Procedures/*methods
MH  - Female
MH  - Humans
MH  - Intracranial Thrombosis/complications
MH  - Male
MH  - Registries
MH  - Risk Factors
MH  - *Stents
MH  - Stroke/*surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - stroke
OT  - thrombectomy
EDAT- 2013/12/05 06:00
MHDA- 2014/02/22 06:00
CRDT- 2013/12/05 06:00
PHST- 2013/12/05 06:00 [entrez]
PHST- 2013/12/05 06:00 [pubmed]
PHST- 2014/02/22 06:00 [medline]
AID - STROKEAHA.113.002407 [pii]
AID - 10.1161/STROKEAHA.113.002407 [doi]
PST - ppublish
SO  - Stroke. 2014 Jan;45(1):141-5. doi: 10.1161/STROKEAHA.113.002407. Epub 2013 Dec 3.

PMID- 25676149
OWN - NLM
STAT- MEDLINE
DCOM- 20161216
LR  - 20161217
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 8
IP  - 4
DP  - 2016 Apr
TI  - Stent retriever thrombectomy with the Cover accessory device versus proximal 
      protection with a balloon guide catheter: in vitro stroke model comparison.
PG  - 413-7
LID - 10.1136/neurintsurg-2014-011617 [doi]
AB  - BACKGROUND: Recently, an in vitro cerebrovascular occlusion model of the 
      intracranial circulation was developed for testing thrombectomy devices. The Cover 
      accessory (Lazarus Effect; Campbell, California, USA) is a novel nitinol braided 
      mesh device that surrounds the stent retrieval device and thrombus during the 
      retrieval process to help prevent clot fragmentation and embolization. METHODS: 
      Using the in vitro model, after introducing fresh clot into the middle cerebral 
      artery, we compared rates of target vessel recanalization and embolization in new 
      territories (areas in which clot had not been introduced) achieved with the 
      Solitaire Flow Restoration (FR) stent retriever (Covidien, Irvine, California) in 
      conjunction with the use of a conventional guide catheter (control group), a balloon 
      guide catheter (BGC group), and the Cover device (Cover group). RESULTS: In a total 
      of 51 thrombectomy experiments (20 in the control group, 20 in the BGC group, and 11 
      in the Cover group), successful recanalization (Thrombolysis in Cerebral Infarction 
      2b-3) was achieved more frequently in the Cover group than in the control group or 
      in the BGC group (p=0.047 and p=0.020, respectively). Embolization of new 
      (previously unaffected) territories occurred in five (25%) experiments from the 
      control group and in three (15%) experiments from the BGC group, whereas no 
      embolization of new territories was seen with Cover device assisted thrombectomy. 
      CONCLUSIONS: Application of the Cover device in this experimental model resulted in 
      higher successful recanalization rates, no embolic events, and was more effective 
      than use of the conventional guide catheter or BGC.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/
FAU - Mokin, Maxim
AU  - Mokin M
AD  - Department of Neurosurgery, University of South Florida College of Medicine, Tampa, 
      Florida, USA Department of Neurology, University of South Florida College of 
      Medicine, Tampa, Florida, USA.
FAU - Setlur Nagesh, Swetadri Vasan
AU  - Setlur Nagesh SV
AD  - Department of Biomedical Engineering, University at Buffalo, State University of New 
      York, Buffalo, New York, USA Department of Electrical Engineering, University at 
      Buffalo, State University of New York, Buffalo, New York, USA Department of 
      Mechanical and Aerospace Engineering, University at Buffalo, State University of New 
      York, Buffalo, New York, USA.
FAU - Ionita, Ciprian N
AU  - Ionita CN
AD  - Department of Biomedical Engineering, University at Buffalo, State University of New 
      York, Buffalo, New York, USA Toshiba Stroke and Vascular Research Center, University 
      at Buffalo, State University of New York, Buffalo, New York, USA.
FAU - Mocco, J
AU  - Mocco J
AD  - Departments of Neurological Surgery and Radiology and Radiological Sciences, Mount 
      Sinai Health System, New York, New York, USA.
FAU - Siddiqui, Adnan H
AU  - Siddiqui AH
AD  - Toshiba Stroke and Vascular Research Center, University at Buffalo, State University 
      of New York, Buffalo, New York, USA Departments of Neurosurgery and Radiology, 
      University at Buffalo, State University of New York, Buffalo, New York, USA Jacobs 
      Institute, Buffalo, New York, USA.
LA  - eng
GR  - 1R01NS064592-01A1/NS/NINDS NIH HHS/United States
GR  - 2R01EB002873/EB/NIBIB NIH HHS/United States
GR  - 5R01EB002873-07/EB/NIBIB NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20150212
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Angiography, Digital Subtraction
MH  - Balloon Occlusion/instrumentation/*methods
MH  - Cerebral Revascularization/instrumentation/*methods
MH  - Humans
MH  - Stroke/diagnostic imaging/*surgery
MH  - Thrombectomy/instrumentation/*methods
MH  - *Vascular Closure Devices
OTO - NOTNLM
OT  - Stent
OT  - Stroke
OT  - Thrombectomy
EDAT- 2015/02/14 06:00
MHDA- 2016/12/17 06:00
CRDT- 2015/02/14 06:00
PHST- 2014/12/16 00:00 [received]
PHST- 2015/01/23 00:00 [accepted]
PHST- 2015/02/14 06:00 [entrez]
PHST- 2015/02/14 06:00 [pubmed]
PHST- 2016/12/17 06:00 [medline]
AID - neurintsurg-2014-011617 [pii]
AID - 10.1136/neurintsurg-2014-011617 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2016 Apr;8(4):413-7. doi: 10.1136/neurintsurg-2014-011617. Epub 
      2015 Feb 12.

PMID- 22552837
OWN - NLM
STAT- MEDLINE
DCOM- 20130723
LR  - 20181113
IS  - 1432-1920 (Electronic)
IS  - 0028-3940 (Linking)
VI  - 54
IP  - 11
DP  - 2012 Nov
TI  - Manual aspiration thrombectomy through balloon-tipped guide catheter for rapid clot 
      burden reduction in endovascular therapy for ICA L/T occlusion.
PG  - 1261-5
LID - 10.1007/s00234-012-1039-3 [doi]
AB  - INTRODUCTION: Timely recanalization during endovascular procedures for acute 
      ischemic stroke can be challenging in cases with large clot burden, such as those 
      encountered in the terminal internal carotid T- or L-type occlusion. METHODS: A 
      novel but simple technique to achieve fast reduction in clot burden in stroke 
      patients with occlusion of the internal carotid artery termination is described 
      where manual suction using a 60-ml syringe applied through an 8-F balloon guide 
      catheter positioned in the cervical carotid vasculature with proximal flow arrest 
      allows subsequent revascularization of the residual middle cerebral artery clot. 
      RESULTS: The use of manual suction through a balloon-tipped guide catheter in 
      internal carotid artery L- or T-type occlusion is illustrated. This resulted in a 
      significant reduction of the clot burden and facilitated further interventions 
      leading to full recanalization. CONCLUSION: Manual suction using a 60-ml syringe 
      through a balloon guide catheter is a useful and feasible technique that facilitates 
      thrombectomy of large burden cerebral clots.
FAU - Eesa, Muneer
AU  - Eesa M
AD  - Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
FAU - Almekhlafi, Mohammed A
AU  - Almekhlafi MA
FAU - Mitha, Alim P
AU  - Mitha AP
FAU - Wong, John H
AU  - Wong JH
FAU - Goyal, Mayank
AU  - Goyal M
LA  - eng
PT  - Journal Article
DEP - 20120428
PL  - Germany
TA  - Neuroradiology
JT  - Neuroradiology
JID - 1302751
SB  - IM
CIN - Neuroradiology. 2012 Nov;54(11):1287. PMID: 22836714
MH  - Carotid Artery Thrombosis/classification/*surgery
MH  - *Carotid Artery, Internal
MH  - Catheters
MH  - Equipment Design
MH  - Humans
MH  - Suction/methods
MH  - Thrombectomy/*instrumentation/*methods
MH  - Time Factors
EDAT- 2012/05/04 06:00
MHDA- 2013/07/24 06:00
CRDT- 2012/05/04 06:00
PHST- 2012/01/16 00:00 [received]
PHST- 2012/04/04 00:00 [accepted]
PHST- 2012/05/04 06:00 [entrez]
PHST- 2012/05/04 06:00 [pubmed]
PHST- 2013/07/24 06:00 [medline]
AID - 10.1007/s00234-012-1039-3 [doi]
PST - ppublish
SO  - Neuroradiology. 2012 Nov;54(11):1261-5. doi: 10.1007/s00234-012-1039-3. Epub 2012 
      Apr 28.

PMID- 28691137
OWN - NLM
STAT- MEDLINE
DCOM- 20181218
LR  - 20191210
IS  - 0942-0940 (Electronic)
IS  - 0001-6268 (Linking)
VI  - 159
IP  - 9
DP  - 2017 Sep
TI  - Effective use of balloon guide catheters in reducing incidence of mechanical 
      thrombectomy related distal embolization.
PG  - 1671-1677
LID - 10.1007/s00701-017-3256-3 [doi]
AB  - BACKGROUND AND PURPOSE: The clinical benefit of endovascular stroke therapy has been 
      demonstrated in several prospective randomized trials. However, in a relevant 
      percentage of patients, mechanical thrombectomy bears the risk of causing new 
      infarction in initially unaffected vascular territories through thrombus 
      fragmentation and migration of clot debris. The goal of this study was to evaluate 
      the use of the balloon guide catheter (BGC) to effectively achieve flow arrest and 
      thrombus aspiration during the intervention to avoid distal embolization. METHODS: A 
      retrospective study was performed in 139 patients between October 2010 and May 2016 
      to analyze occlusions in the middle cerebral artery (MCA) or internal carotid artery 
      (ICA) by using a stent retriever with a BGC (n = 73) or a non-BGC (n = 66). The 
      following data were collected: patient age and gender, along with history of 
      diabetes mellitus, hypertension, atrial fibrillation, smoking, obesity, 
      dyslipidemia, and previous ischemic stroke. Data on procedure time, number of 
      passes, and angiographic findings were also collected. The final reperfusion score 
      was rated based on the Thrombolysis in Cerebral Infarction (TICI) grading scale. 
      Successful recanalization was defined as TICI 3 or 2b. RESULTS: A total of 139 
      patients underwent mechanical thrombectomy with the stent retriever. Of the 139 
      patients, 73 (52.5%) underwent placement of a BGC. The mean age was 
      65.8 ± 13.5 years, and the median National Institutes of Health Stroke Scale (NIHSS) 
      score was 11. The average initial NIHSS score was lower in the BGC group compared 
      with the non-BGC group (mean, 11.2 ± 5.6 vs. 13.2 ± 5.6; P = 0.03). Patients with 
      BGC had fewer incidences of previous ischemic stroke (12.3% vs. 28.8%; P = 0.01). 
      The numbers of passes were similar between the two groups. The procedure time 
      (99 ± 49.4 min vs. 124 ± 72.2 min; P = 0.02) and the time from onset of symptoms to 
      procedure end (302 ± 102 min vs. 357.2 ± 136.1 min; P = 0.009) were shorter in the 
      BGC group. TICI 3 or 2b recanalization scores were higher in the BGC group compared 
      to the non-BGC group [63/73, 86.3% vs. 48/66, 72.7%; odds ratio (OR), 0.6; 95% 
      confidence interval (CI), 0.2-1.4; P = 0.04]. Importantly, distal embolization was 
      less frequent in the BGC group (5/73, 6.8% vs. 21/66, 31.8%; OR, 6.3; 95% CI, 
      2.2-18.0; P < 0.001). CONCLUSIONS: The risk of distal embolization was significantly 
      decreased with the use of a BGC.
FAU - Lee, Dong Hoon
AU  - Lee DH
AD  - Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of 
      Korea, 93 Jungbu-daero Paldal-gu, Suwon, 16247, South Korea.
FAU - Sung, Jae Hoon
AU  - Sung JH
AD  - Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of 
      Korea, 93 Jungbu-daero Paldal-gu, Suwon, 16247, South Korea. jaehoonsung@gmail.com.
FAU - Kim, Sang Uk
AU  - Kim SU
AD  - Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of 
      Korea, 93 Jungbu-daero Paldal-gu, Suwon, 16247, South Korea.
FAU - Yi, Ho Jun
AU  - Yi HJ
AD  - Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of 
      Korea, 93 Jungbu-daero Paldal-gu, Suwon, 16247, South Korea.
FAU - Hong, Jae Taek
AU  - Hong JT
AD  - Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of 
      Korea, 93 Jungbu-daero Paldal-gu, Suwon, 16247, South Korea.
FAU - Lee, Sang Won
AU  - Lee SW
AD  - Department of Neurosurgery, St. Vincent's Hospital, The Catholic University of 
      Korea, 93 Jungbu-daero Paldal-gu, Suwon, 16247, South Korea.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20170709
PL  - Austria
TA  - Acta Neurochir (Wien)
JT  - Acta neurochirurgica
JID - 0151000
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Embolization, Therapeutic/adverse effects/*methods
MH  - Female
MH  - Humans
MH  - Infarction, Middle Cerebral Artery/surgery/*therapy
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/epidemiology/prevention & control
MH  - Thrombectomy/*adverse effects/methods
OTO - NOTNLM
OT  - Balloon-guided catheter
OT  - Distal embolization
OT  - Mechanical thrombectomy
EDAT- 2017/07/12 06:00
MHDA- 2018/12/19 06:00
CRDT- 2017/07/11 06:00
PHST- 2017/04/04 00:00 [received]
PHST- 2017/06/19 00:00 [accepted]
PHST- 2017/07/12 06:00 [pubmed]
PHST- 2018/12/19 06:00 [medline]
PHST- 2017/07/11 06:00 [entrez]
AID - 10.1007/s00701-017-3256-3 [pii]
AID - 10.1007/s00701-017-3256-3 [doi]
PST - ppublish
SO  - Acta Neurochir (Wien). 2017 Sep;159(9):1671-1677. doi: 10.1007/s00701-017-3256-3. 
      Epub 2017 Jul 9.

PMID- 32457694
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200529
IS  - 1664-2295 (Print)
IS  - 1664-2295 (Electronic)
IS  - 1664-2295 (Linking)
VI  - 11
DP  - 2020
TI  - Effect of Balloon Guide Catheter Utilization on the Incidence of Sub-angiographic 
      Peripheral Emboli on High-Resolution DWI After Thrombectomy: A Prospective 
      Observational Study.
PG  - 386
LID - 10.3389/fneur.2020.00386 [doi]
LID - 386
AB  - Background: Thrombus fragmentation causing distal emboli is a feared complication 
      during mechanical thrombectomy (MT). We aimed to investigate the impact of 
      procedural parameters and thrombus properties on the incidence of peripheral emboli 
      after MT for large vessel occlusions (LVO). Methods: We performed a prospective 
      analysis of patients with LVO stroke successfully treated with MT, defined as a 
      score of 2b, 2c, or 3 on the thrombolysis in cerebral infarction (TICI) scale. A 
      follow-up MRI including high-resolution diffusion-weighted imaging (DWI) was 
      performed within 24 h following MT. The primary endpoint was the number and volume 
      of peripheral emboli, classified as punctuate DWI lesions distant to the 
      diffusion-restricted core lesion. Further analysis included the influence of 
      baseline characteristics, procedural and outcome parameters, and thrombus properties 
      on peripheral emboli. Results: Thirty-seven patients with successful MT met the 
      inclusion criteria. Use of a balloon guide catheter (BGC) and TICI were the only 
      independent predictors for a reduced number of peripheral emboli. The use of a BGC 
      led to a significant reduction in the number and volume of peripheral emboli, with a 
      median number/volume of peripheral emboli of 4.5/287 μl (IQR 1.25-8.25/76-569 μl) 
      vs. 12/938 μl (IQR 4-19/242-1,836 μl). In cases where BGC was not employed, the 
      number of peripheral emboli increased with decreasing TICI scores. Conclusions: 
      BGC-aided MT reduces the number of peripheral emboli in successful but incomplete 
      reperfusion (TICI 2b and 2c). The effectiveness of this strategy therefore goes 
      above and beyond that which can be demonstrated by the TICI score alone.
CI  - Copyright © 2020 Schönfeld, Kabiri, Kniep, Meyer, McDonough, Sedlacik, Ernst, 
      Broocks, Faizy, Schön, Cheng, Thomalla, Fiehler and Hanning.
FAU - Schönfeld, Michael H
AU  - Schönfeld MH
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Kabiri, Reza
AU  - Kabiri R
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Kniep, Helge C
AU  - Kniep HC
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Meyer, Lukas
AU  - Meyer L
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - McDonough, Rosalie
AU  - McDonough R
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Sedlacik, Jan
AU  - Sedlacik J
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
AD  - Biomedical Engineering Department, Centre for the Developing Brain, School of 
      Biomedical Engineering & Imaging Sciences, King's College London, London, United 
      Kingdom.
FAU - Ernst, Marielle
AU  - Ernst M
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Broocks, Gabriel
AU  - Broocks G
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Faizy, Tobias
AU  - Faizy T
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Schön, Gerhard
AU  - Schön G
AD  - Institute of Medical Biometry and Epidemiology, University Medical Center 
      Hamburg-Eppendorf, Hamburg, Germany.
FAU - Cheng, Bastian
AU  - Cheng B
AD  - Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, 
      Germany.
FAU - Thomalla, Götz
AU  - Thomalla G
AD  - Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, 
      Germany.
FAU - Fiehler, Jens
AU  - Fiehler J
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
FAU - Hanning, Uta
AU  - Hanning U
AD  - Department of Diagnostic and Interventional Neuroradiology, University Medical 
      Center Hamburg-Eppendorf, Hamburg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20200507
TA  - Front Neurol
JT  - Frontiers in neurology
JID - 101546899
PMC - PMC7221024
OTO - NOTNLM
OT  - cerebrovascular disease/stroke
OT  - embolism
OT  - ischemic stroke
OT  - magnetic resonance imaging (MRI)
OT  - revascularization
EDAT- 2020/05/28 06:00
MHDA- 2020/05/28 06:01
CRDT- 2020/05/28 06:00
PHST- 2020/01/31 00:00 [received]
PHST- 2020/04/17 00:00 [accepted]
PHST- 2020/05/28 06:00 [entrez]
PHST- 2020/05/28 06:00 [pubmed]
PHST- 2020/05/28 06:01 [medline]
AID - 10.3389/fneur.2020.00386 [doi]
PST - epublish
SO  - Front Neurol. 2020 May 7;11:386. doi: 10.3389/fneur.2020.00386. eCollection 2020.

PMID- 24627111
OWN - NLM
STAT- MEDLINE
DCOM- 20140703
LR  - 20181202
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 45
IP  - 5
DP  - 2014 May
TI  - Response to letter regarding article, "Balloon guide catheter improves 
      revascularization and clinical outcomes with the solitaire device: analysis of the 
      North American Solitaire Acute Stroke Registry".
PG  - e86
LID - 10.1161/STROKEAHA.114.004828 [doi]
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - Neurology, Neurosurgery, Radiology, Boston Medical Center, Boston, MA.
FAU - Malisch, Timothy W
AU  - Malisch TW
FAU - Zaidat, Osama O
AU  - Zaidat OO
CN  - North American Solitaire Acute Stroke Registry
LA  - eng
PT  - Comment
PT  - Letter
DEP - 20140313
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
CON - Stroke. 2014 Jan;45(1):141-5. PMID: 24302483
CON - Stroke. 2014 May;45(5):e85. PMID: 24627115
MH  - Catheterization, Central Venous/*methods
MH  - Cerebral Revascularization/*methods
MH  - Endovascular Procedures/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - *Stents
MH  - Stroke/*surgery
EDAT- 2014/03/15 06:00
MHDA- 2014/07/06 06:00
CRDT- 2014/03/15 06:00
PHST- 2014/03/15 06:00 [entrez]
PHST- 2014/03/15 06:00 [pubmed]
PHST- 2014/07/06 06:00 [medline]
AID - STROKEAHA.114.004828 [pii]
AID - 10.1161/STROKEAHA.114.004828 [doi]
PST - ppublish
SO  - Stroke. 2014 May;45(5):e86. doi: 10.1161/STROKEAHA.114.004828. Epub 2014 Mar 13.

PMID- 28963367
OWN - NLM
STAT- MEDLINE
DCOM- 20180903
LR  - 20181202
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Print)
IS  - 1759-8478 (Linking)
VI  - 10
IP  - 6
DP  - 2018 Jun
TI  - TREVO stent-retriever mechanical thrombectomy for acute ischemic stroke secondary to 
      large vessel occlusion registry.
PG  - 516-524
LID - 10.1136/neurintsurg-2017-013328 [doi]
AB  - BACKGROUND: Recent randomized clinical trials (RCTs) demonstrated the efficacy of 
      mechanical thrombectomy using stent-retrievers in patients with acute ischemic 
      stroke (AIS) with large vessel occlusions; however, it remains unclear if these 
      results translate to a real-world setting. The TREVO Stent-Retriever Acute Stroke 
      (TRACK) multicenter Registry aimed to evaluate the use of the Trevo device in 
      everyday clinical practice. METHODS: Twenty-three centers enrolled consecutive AIS 
      patients treated from March 2013 through August 2015 with the Trevo device. The 
      primary outcome was deﬁned as achieving a Thrombolysis in Cerebral Infarction (TICI) 
      score of ≥2b. Secondary outcomes included 90-day modified Rankin Scale (mRS), 
      mortality, and symptomatic intracranial hemorrhage (sICH). RESULTS: A total of 
      634patients were included. Mean age was 66.1±14.8 years and mean baseline NIH Stroke 
      Scale (NIHSS) score was 17.4±6.7; 86.7% had an anterior circulation occlusion. Mean 
      time from symptom onset to puncture and time to revascularization were 
      363.1±264.5 min and 78.8±49.6 min, respectively. 80.3% achieved TICI ≥2b. 90-day mRS 
      ≤2 was achieved in 47.9%, compared with 51.4% when restricting the analysis to the 
      anterior circulation and within 6 hours (similar to recent AHA/ASA guidelines), and 
      54.3% for those who achieved complete revascularization. The 90-day mortality rate 
      was 19.8%. Independent predictors of clinical outcome included age, baseline NIHSS, 
      use of balloon guide catheter, revascularization, and sICH. CONCLUSION: The TRACK 
      Registry results demonstrate the generalizability of the recent thrombectomy RCTs in 
      real-world clinical practice. No differences in clinical and angiographic outcomes 
      were shown between patients treated within the AHA/ASA guidelines and those treated 
      outside the recommendations.
CI  - © Article author(s) (or their employer(s) unless otherwise stated in the text of the 
      article) 2018. All rights reserved. No commercial use is permitted unless otherwise 
      expressly granted.
FAU - Zaidat, Osama O
AU  - Zaidat OO
AD  - Departments of Endovascular Neurosurgery and Stroke, St Vincent Mercy Medical 
      Center, Toledo, Ohio, USA.
AD  - Neuroscience & Stroke Center, Mercy Health St Vincent Hospital, Toledo, OH, USA.
FAU - Castonguay, Alicia C
AU  - Castonguay AC
AD  - Department of Biostatistics, University of Texas, Houston, Texas, USA.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
FAU - English, Joey D
AU  - English JD
AD  - California Pacific Medical Center, Atlanta, Florida, USA.
FAU - Satti, Sudhakar R
AU  - Satti SR
AD  - Department of Neurointerventional Surgery, Christiana Care Health System, Newark, 
      Delaware, USA.
FAU - Chen, Jennifer
AU  - Chen J
AD  - Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.
FAU - Farid, Hamed
AU  - Farid H
AD  - Department of Neurointerventional Radiology, St Jude Medical Center, Fullerton, USA.
FAU - Borders, Candace
AU  - Borders C
AD  - University of California, Irvine School of Medicine, Irvine, California, USA.
FAU - Veznedaroglu, Erol
AU  - Veznedaroglu E
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, 
      Pennsylvania, USA.
FAU - Binning, Mandy J
AU  - Binning MJ
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, 
      Pennsylvania, USA.
FAU - Puri, Ajit
AU  - Puri A
AD  - Department of Radiology, University of Massachusetts Medical School, Worcester, 
      Massachusetts, USA.
FAU - Vora, Nirav A
AU  - Vora NA
AD  - Department of Radiology, Riverside Radiology and Interventional Associates, 
      Columbus, Ohio, USA.
FAU - Budzik, Ron F
AU  - Budzik RF
AD  - Department of Radiology, Riverside Radiology and Interventional Associates, 
      Columbus, Ohio, USA.
FAU - Dabus, Guilherme
AU  - Dabus G
AD  - Department of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, 
      Miami, Florida, USA.
FAU - Linfante, Italo
AU  - Linfante I
AD  - Department of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, 
      Miami, Florida, USA.
FAU - Janardhan, Vallabh
AU  - Janardhan V
AD  - Texas Stroke Institute, Plano, Texas, USA.
FAU - Alshekhlee, Amer
AU  - Alshekhlee A
AD  - Department of Vascular and Interventional Neurology, DePaul Stroke Center-SSM 
      Neuroscience Institutes, St Louis University, St Louis, Missouri, USA.
FAU - Abraham, Michael G
AU  - Abraham MG
AD  - Departments of Neurology and Interventional Radiology, University of Kansas Medical 
      Center, Kansas, USA.
FAU - Edgell, Randall
AU  - Edgell R
AD  - Department of Neurology, St Louis University, St Louis, Missouri, USA.
FAU - Taqi, Muhammad Asif
AU  - Taqi MA
AD  - Department of Neurology and Neurosurgery, Los Robles Hospital and Medical Center, 
      Thousand Oaks, California, USA.
FAU - Khoury, Ramy El
AU  - Khoury RE
AD  - Department of Neurology, Tulane University, New Orleans, Louisiana, USA.
FAU - Mokin, Maxim
AU  - Mokin M
AD  - Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, 
      Florida, USA.
FAU - Majjhoo, Aniel Q
AU  - Majjhoo AQ
AD  - Department of Neurology, Wayne State School of Medicine, Detroit, Michigan, USA.
FAU - Kabbani, Mouhammed R
AU  - Kabbani MR
AD  - Department of Neurosurgery, Gundersen Health System, La Crosse, Wisconsin, USA.
FAU - Froehler, Michael T
AU  - Froehler MT
AD  - Departments of Neurology, Neurosurgery, and Radiology, Vanderbilt University Medical 
      Center, Nashville, Tennessee, USA.
FAU - Finch, Ira
AU  - Finch I
AD  - John Muir Health, Walnut Creek, California, USA.
FAU - Ansari, Sameer A
AU  - Ansari SA
AD  - Departments of Radiology, Neurology, and Neurological Surgery, Northwestern 
      University, Feinberg School of Medicine, Chicago, Illinois, USA.
FAU - Novakovic, Roberta
AU  - Novakovic R
AD  - Departments of Radiology, Neurology, and Neurotherapeutics, UT Southwestern Medical 
      Center, Dallas, Texas, USA.
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - Department of Neurology, Neurosurgery, and Radiology, Boston Medical Center, Boston, 
      Massachusetts, USA.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20170929
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Ischemia/diagnostic imaging/*surgery
MH  - Cerebrovascular Disorders/diagnostic imaging/*surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Registries
MH  - Retrospective Studies
MH  - *Stents
MH  - Stroke/diagnostic imaging/*surgery
MH  - Thrombectomy/instrumentation/*methods
MH  - Treatment Outcome
PMC - PMC5969387
OTO - NOTNLM
OT  - mechanical
OT  - revascularization
OT  - stent-retriever
OT  - stroke
OT  - thrombectomy
OT  - trevo
COIS- Competing interests: IL is consultant for Metronic, Stryker, Penumbra, and Cordis. 
      MM is consultant for Claret Medical, Nogueira-Stryker Neurovascular (Trevo-2 Trial 
      Principal Investigator – modest; DAWN Trial Principal Investigator – no 
      compensation, TREVO Registry Steering Committee – no compensation), Medtronic (SWIFT 
      Trial Steering Committee – modest; SWIFT-Prime Trial Steering Committee – no 
      compensation; STAR Trial Angiographic Core Lab – significant), Penumbra (3D 
      Separator Trial Executive Committee – no compensation), Neuravi (ARISE-2 Steering 
      Committee – no compensation), Genentech (Physician Advisory Board – modest), Allm 
      Inc (Physician Advisory Board – no compensation), Editor-In-Chief Interventional 
      Neurology Journal (no compensation). SRS is a consultant for Stryker Neurovascular. 
      OOZ is overall PI for TRACK – no compensation, Arise II – modest, Co-PI Therapy 
      Trial – modest, Steering committee STRATIS registry – modest.
EDAT- 2017/10/01 06:00
MHDA- 2018/09/04 06:00
CRDT- 2017/10/01 06:00
PHST- 2017/07/17 00:00 [received]
PHST- 2017/08/17 00:00 [revised]
PHST- 2017/08/24 00:00 [accepted]
PHST- 2017/10/01 06:00 [pubmed]
PHST- 2018/09/04 06:00 [medline]
PHST- 2017/10/01 06:00 [entrez]
AID - neurintsurg-2017-013328 [pii]
AID - 10.1136/neurintsurg-2017-013328 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2018 Jun;10(6):516-524. doi: 10.1136/neurintsurg-2017-013328. 
      Epub 2017 Sep 29.

PMID- 24627115
OWN - NLM
STAT- MEDLINE
DCOM- 20140703
LR  - 20181202
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 45
IP  - 5
DP  - 2014 May
TI  - Letter by Simonsen et al regarding article, "Balloon guide catheter improves 
      revascularization and clinical outcomes with the solitaire device: analysis of the 
      North American Solitaire Acute Stroke Registry".
PG  - e85
LID - 10.1161/STROKEAHA.114.004789 [doi]
FAU - Simonsen, Claus Z
AU  - Simonsen CZ
AD  - Department of Neurology.
FAU - Sørensen, Leif H
AU  - Sørensen LH
FAU - Andersen, Grethe
AU  - Andersen G
LA  - eng
PT  - Comment
PT  - Letter
DEP - 20140313
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
CON - Stroke. 2014 Jan;45(1):141-5. PMID: 24302483
CIN - Stroke. 2014 May;45(5):e86. PMID: 24627111
MH  - Catheterization, Central Venous/*methods
MH  - Cerebral Revascularization/*methods
MH  - Endovascular Procedures/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - *Stents
MH  - Stroke/*surgery
EDAT- 2014/03/15 06:00
MHDA- 2014/07/06 06:00
CRDT- 2014/03/15 06:00
PHST- 2014/03/15 06:00 [entrez]
PHST- 2014/03/15 06:00 [pubmed]
PHST- 2014/07/06 06:00 [medline]
AID - STROKEAHA.114.004789 [pii]
AID - 10.1161/STROKEAHA.114.004789 [doi]
PST - ppublish
SO  - Stroke. 2014 May;45(5):e85. doi: 10.1161/STROKEAHA.114.004789. Epub 2014 Mar 13.

PMID- 30612534
OWN - NLM
STAT- MEDLINE
DCOM- 20191016
LR  - 20191016
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 50
IP  - 2
DP  - 2019 Feb
TI  - Vertebral Artery Patency and Thrombectomy in Basilar Artery Occlusions.
PG  - 389-395
LID - 10.1161/STROKEAHA.118.022466 [doi]
AB  - Background and Purpose- Factors influencing recanalization success in basilar artery 
      occlusions are largely unknown. Preliminary evidence has suggested that flow arrest 
      in the vertebral artery contralateral to the catheter bearing vertebral artery may 
      facilitate recanalization. The aim of this analysis was to assess the impact of 
      anatomic variations and flow conditions on recanalization success in basilar artery 
      occlusion treated with mechanical thrombectomy. Methods- Consecutive basilar artery 
      occlusions treated with second-generation thrombectomy devices at a single-center 
      were retrospectively analyzed. Baseline patients' characteristics, occlusion length, 
      collateral circulation, underlying stenosis, incomplete occlusions, and patency of 
      the vertebral arteries were analyzed with regards to recanalization success. 
      Aplastic or hypoplastic vertebral artery contralateral to the catheter position was 
      defined as contralateral low flow condition. Logistic regression analysis was used 
      to examine the association between anatomic variations and flow conditions in 
      relation to complete recanalization and the modified Rankin Scale score while 
      controlling for several potentially confounding variables. Clinical impact was 
      evaluated using the modified Rankin Scale score of ≤3. Results- One hundred fifteen 
      patients were included (mean age 71.5±12.8, m:f=2:1, median National Institutes of 
      Health Stroke Scale =15, interquartile range =10-22). Complete recanalization was 
      more often observed in patients with contralateral low flow conditions (80.6% versus 
      50.0%), which remained an independent predictor of complete recanalization in 
      multivariable analysis (adjusted odds ratio, 5.81; 95% CI, 1.97-17.19). Patients 
      with complete posterior recanalization had lower in-hospital mortality (16.4% versus 
      41.7%) and more often achieved modified Rankin Scale score of ≤3 (49.4% versus 
      8.3%), even after adjusting for potential confounders (adjusted odds ratio, 15.93; 
      95% CI, 1.42-179.00). Conclusions- Contralateral low flow condition (vertebral 
      artery aplasia or hypoplasia) seems to be an independent factor for fewer distal 
      emboli and complete recanalization in basilar artery occlusion patients treated by 
      modern endovascular devices. Complete recanalization reflecting the absence of 
      peri-interventional clot fragmentation brings clear clinical benefit. Further 
      studies are warranted to evaluate the need for contralateral flow modulation or 
      ipsilateral balloon guide catheter during posterior circulation thrombectomy in 
      patients with bilaterally patent vertebral arteries.
FAU - Boeckh-Behrens, Tobias
AU  - Boeckh-Behrens T
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Pree, David
AU  - Pree D
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Lummel, Nina
AU  - Lummel N
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Friedrich, Benjamin
AU  - Friedrich B
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Maegerlein, Christian
AU  - Maegerlein C
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Kreiser, Kornelia
AU  - Kreiser K
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Kirschke, Jan
AU  - Kirschke J
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Berndt, Maria
AU  - Berndt M
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Lehm, Manuel
AU  - Lehm M
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Wunderlich, Silke
AU  - Wunderlich S
FAU - Mosimann, Pascal J
AU  - Mosimann PJ
AD  - Department of Neurology (P.J.M., J.K.), Klinikum Rechts der Isar, Technical 
      University Munich, Germany.
AD  - Institute of Diagnostic and Interventional Neuroradiology (P.J.M., J.K.), University 
      Hospital Bern, Inselspital, University of Bern, Switzerland.
FAU - Fischer, Urs
AU  - Fischer U
AD  - Department of Neurology (U.F., J.K.), University Hospital Bern, Inselspital, 
      University of Bern, Switzerland.
FAU - Zimmer, Claus
AU  - Zimmer C
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
FAU - Kaesmacher, Johannes
AU  - Kaesmacher J
AD  - From the Department of Diagnostic and Interventional Neuroradiology (T.B.-B., D.P., 
      N.L., B.F., C.M., K.K., J.K., M.B., M.L., C.Z., J.K.), Klinikum Rechts der Isar, 
      Technical University Munich, Germany.
AD  - Department of Neurology (P.J.M., J.K.), Klinikum Rechts der Isar, Technical 
      University Munich, Germany.
AD  - Institute of Diagnostic and Interventional Neuroradiology (P.J.M., J.K.), University 
      Hospital Bern, Inselspital, University of Bern, Switzerland.
AD  - Department of Neurology (U.F., J.K.), University Hospital Bern, Inselspital, 
      University of Bern, Switzerland.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Flow Velocity
MH  - Disease-Free Survival
MH  - Female
MH  - *Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Survival Rate
MH  - *Thrombectomy
MH  - *Vascular Patency
MH  - *Vertebral Artery/diagnostic imaging/physiopathology
MH  - *Vertebrobasilar Insufficiency/diagnostic imaging/mortality/physiopathology/surgery
OTO - NOTNLM
OT  - *anatomy
OT  - *catheter
OT  - *stroke
OT  - *thrombectomy
OT  - *vertebral artery
EDAT- 2019/01/08 06:00
MHDA- 2019/10/17 06:00
CRDT- 2019/01/08 06:00
PHST- 2019/01/08 06:00 [pubmed]
PHST- 2019/10/17 06:00 [medline]
PHST- 2019/01/08 06:00 [entrez]
AID - 10.1161/STROKEAHA.118.022466 [doi]
PST - ppublish
SO  - Stroke. 2019 Feb;50(2):389-395. doi: 10.1161/STROKEAHA.118.022466.

PMID- 31318624
OWN - NLM
STAT- MEDLINE
DCOM- 20200312
LR  - 20200312
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 50
IP  - 9
DP  - 2019 Sep
TI  - Site Experience and Outcomes in the Trevo Acute Ischemic Stroke (TRACK) Multicenter 
      Registry.
PG  - 2455-2460
LID - 10.1161/STROKEAHA.118.024639 [doi]
AB  - Background and Purpose- It remains unclear how experience influences outcomes after 
      the advent of stent retriever technology. We studied the relationship between site 
      experience and outcomes in the Trevo Acute Ischemic Stroke multicenter registry. 
      Methods- The 24 sites that enrolled patients in the Trevo Acute Ischemic Stroke 
      registry were trichotomized into low-volume (<2 cases/month), medium-volume (2-4 
      cases/month), and high-volume centers (>4 cases/month). Baseline features, imaging, 
      and clinical outcomes were compared across the 3 volume strata. A multivariable 
      analysis was performed to assess whether outcomes were influenced by site volumes. 
      Results- A total of 624 patients were included and distributed as low- (n=188 
      patients, 30.1%), medium- (n=175, 28.1%), and high-volume (n=261, 41.8%) centers. 
      There were no significant differences in terms of age (mean, 66±16 versus 67±14 
      versus 65±15; P=0.2), baseline National Institutes of Health Stroke Scale (mean, 
      17.6±6.5 versus 16.8±6.5 versus 17.6±6.9; P=0.43), or occlusion site across the 3 
      groups. Median (interquartile range) times from stroke onset to groin puncture were 
      266 (181.8-442.5), 239 (175-389), and 336.5 (221.3-466.5) minutes in low-, medium-, 
      and high-volume centers, respectively (P=0.004). Higher efficiency and better 
      outcomes were seen in higher volume sites as demonstrated by shorter procedural 
      times (median, 97 versus 67 versus 69 minutes; P<0.001), higher balloon guide 
      catheter use (40% versus 36% versus 59%; P≤0.0001), and higher rates of good outcome 
      (90-day modified Rankin Scale [mRS], ≤2; 39% versus 50% versus 53.4%; P=0.02). There 
      were no appreciable differences in symptomatic intracranial hemorrhage or 90-day 
      mortality. After adjustments in the multivariable analysis, there were significantly 
      higher chances of achieving a good outcome in high- versus low-volume (odds ratio, 
      1.67; 95% CI, 1.03-2.7; P=0.04) and medium- versus low-volume (odds ratio, 1.75; 95% 
      CI, 1.1-2.9; P=0.03) centers, but there were no significant differences between 
      high- and medium-volume centers (P=0.86). Conclusions- Stroke center volumes 
      significantly influence efficiency and outcomes in mechanical thrombectomy.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - From the Department of Neurology, Emory University School of Medicine, Atlanta, GA 
      (R.G.N., D.C.H., L.C.R., M.R.F.).
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - From the Department of Neurology, Emory University School of Medicine, Atlanta, GA 
      (R.G.N., D.C.H., L.C.R., M.R.F.).
FAU - Castonguay, Alicia
AU  - Castonguay A
AD  - Department of Neurology, University of Toledo, OH (A.C.).
FAU - Rebello, Leticia C
AU  - Rebello LC
AD  - From the Department of Neurology, Emory University School of Medicine, Atlanta, GA 
      (R.G.N., D.C.H., L.C.R., M.R.F.).
FAU - Abraham, Michael
AU  - Abraham M
AD  - Department of Neurology, University of Kansas Medical Center, University of 
      Massachusetts Medical School, Worcester (M.A.).
FAU - Puri, Ajit
AU  - Puri A
AD  - Department of Neurosurgery, University of Massachusetts Medical School, Worcester 
      (A.P.).
AD  - Department of Radiology, University of Massachusetts Medical School, Worcester 
      (A.P.).
FAU - Alshekhlee, Amer
AU  - Alshekhlee A
AD  - Department of Neurology, SSM Neuroscience Institutes, DePaul Health, Bridgeton, MO 
      (A.A.).
FAU - Majjhoo, Aniel
AU  - Majjhoo A
AD  - Department of Neurology, McLaren Flint Neuroscience Institute, Flint, MI (A.M.).
AD  - Department of Neurology, McLaren Flint Neuroscience Institute, Flint, MI (A.M.).
FAU - Farid, Hamed
AU  - Farid H
AD  - Neurointerventional Radiology, St. Jude Medical Center, Chicago, IL (H.F.).
FAU - Finch, Ira
AU  - Finch I
AD  - Department of Interventional Radiology, John Muir Medical Center, Walnut Creek, CA 
      (I.F.).
FAU - English, Joey
AU  - English J
AD  - Department of Neurology, California Pacific Medical Center, San Francisco (J.E.).
FAU - Mokin, Maxim
AU  - Mokin M
AD  - Department of Neurosurgery and Brain Repair, University of South Florida, Tampa 
      (M.M.).
FAU - Froehler, Michael T
AU  - Froehler MT
AD  - Cerebrovascular Program, Neurosurgery, Radiology, Vanderbilt University Medical 
      Center, Nashville, TN (M.T.F.).
FAU - Kabbani, Mo
AU  - Kabbani M
AD  - Department of Neurointervention, Gundersen Lutheran Medical Foundation, Inc, La 
      Crosse, WI (M.K.).
FAU - Taqi, Muhammad A
AU  - Taqi MA
AD  - Department of Neurology, Desert Regional Medical Center, Palm Springs, CA (M.A.T.).
FAU - Vora, Nirav
AU  - Vora N
AD  - Department of Neuroradiology, Riverside Radiology, Columbus, OH (N.V., R.B.).
FAU - Khoury, Ramy El
AU  - Khoury RE
AD  - Department of Neurology, Tulane University School of Medicine, New Orleans, LA 
      (R.E.K.).
FAU - Edgell, Randall C
AU  - Edgell RC
AD  - Department of Surgery, Saint Louis University Hospital, St. Louis, MO (R.C.E.).
AD  - Department of Neurology, Saint Louis University Hospital, St. Louis, MO (R.C.E.).
FAU - Novakovic, Roberta
AU  - Novakovic R
AD  - Department of Radiology, University of Texas Southwestern, Dallas (R.N.).
AD  - Department of Neurology, University of Texas Southwestern, Dallas (R.N.).
FAU - Nguyen, Thanh
AU  - Nguyen T
AD  - Department of and Neurotherapeutics, University of Texas Southwestern, Dallas 
      (R.N.).
AD  - Department of Neurology, Boston Medical Center, MA (T.N.).
AD  - Department of Neurosurgery, Boston Medical Center, MA (T.N.).
FAU - Janardhan, Vallabh
AU  - Janardhan V
AD  - Department of Radiology, Boston Medical Center, MA (T.N.).
FAU - Veznedaroglu, Enrol
AU  - Veznedaroglu E
AD  - Department of Neurology, Texas Stroke Institute, Plano (V.J.).
FAU - Prabhakaran, Shyam
AU  - Prabhakaran S
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, PA (E.V.).
FAU - Budzik, Ron
AU  - Budzik R
AD  - Department of Neuroradiology, Riverside Radiology, Columbus, OH (N.V., R.B.).
FAU - Frankel, Michael R
AU  - Frankel MR
AD  - From the Department of Neurology, Emory University School of Medicine, Atlanta, GA 
      (R.G.N., D.C.H., L.C.R., M.R.F.).
FAU - Nordhaus, Brittany L
AU  - Nordhaus BL
AD  - Department of Neurology, Northwestern University, Chicago, IL (S.P.).
FAU - Zaidat, Osama O
AU  - Zaidat OO
AD  - Department of Neurosciences, Mercy Health-St. Vincent Medical Center, Toledo, OH 
      (B.L.N., O.O.Z.).
LA  - eng
PT  - Journal Article
DEP - 20190718
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Brain Ischemia/*mortality/therapy
MH  - Female
MH  - Humans
MH  - Intracranial Hemorrhages/*mortality/therapy
MH  - Ischemia/therapy
MH  - Male
MH  - Middle Aged
MH  - Registries
MH  - Stents/adverse effects
MH  - Stroke/*mortality/therapy
MH  - *Thrombectomy/adverse effects/methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - *brain ischemia
OT  - *groin
OT  - *humans
OT  - *stents
OT  - *thrombectomy
EDAT- 2019/07/19 06:00
MHDA- 2020/03/13 06:00
CRDT- 2019/07/19 06:00
PHST- 2019/07/19 06:00 [pubmed]
PHST- 2020/03/13 06:00 [medline]
PHST- 2019/07/19 06:00 [entrez]
AID - 10.1161/STROKEAHA.118.024639 [doi]
PST - ppublish
SO  - Stroke. 2019 Sep;50(9):2455-2460. doi: 10.1161/STROKEAHA.118.024639. Epub 2019 Jul 
      18.

PMID- 31072248
OWN - NLM
STAT- MEDLINE
DCOM- 20200227
LR  - 20200227
IS  - 2385-2011 (Electronic)
IS  - 1591-0199 (Print)
IS  - 1591-0199 (Linking)
VI  - 25
IP  - 5
DP  - 2019 Oct
TI  - Procedural approaches and angiographic signs predicting first-pass recanalization in 
      patients treated with mechanical thrombectomy for acute ischaemic stroke.
PG  - 491-496
LID - 10.1177/1591019919847623 [doi]
AB  - BACKGROUND: First-pass recanalization via mechanical thrombectomy (MT) has been 
      associated with improved clinical outcome in patients with acute ischaemic stroke. 
      The optimal approach to achieve first-pass effect (FPE) remains unclear. No study 
      has evaluated angiographic features associated with the achievement of FPE. We aimed 
      to determine the procedural approaches and angiographic signs that may predict FPE. 
      METHODS: We performed a prospective, multi-centre, observational study of FPE in 
      patients with anterior circulation stroke treated with MT between February and June 
      2017. MTs were performed using different devices, deployment manoeuvres (standard 
      versus 'Push and Fluff' technique), proximal balloon guide catheter (PBGC), distal 
      aspiration catheter (DAC) or both. The angiographic clot protrusion sign (ACPS) was 
      recorded. Completed FPE (cFPE) was defined as a modified thrombolysis in cerebral 
      infarction score of 2c-3. Associations were sought between cFPE and procedural 
      approaches and angiographic signs. RESULTS: A total of 193 patients were included. 
      cFPE was achieved in 74 (38.3%) patients. The use of the push and fluff technique 
      (odds ratio (OR) 3.45, 95% confidence interval (CI): 1.28-9.29, p = 0.010), PBGC (OR 
      3.81, 95% CI: 1.41-10.22, p = 0.008) and ACPS (OR 4.71, 95% CI: 1.78-12.44, 
      p = 0.002) were independently associated with cFPE. Concurrence of these three 
      variables led to cFPE in 82 vs 35% of the remaining cases (p = 0.002). CONCLUSIONS: 
      The concurrence of the PBGC, the push and fluff technique, and the ACPS was 
      associated with the highest rates of cFPE. Appropriate selection of the thrombectomy 
      device and deployment technique may lead to better procedural outcomes. ACPS could 
      be used to assess clot integration strategies in future trials.
FAU - Tomasello, Alejandro
AU  - Tomasello A
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Ribò, Marc
AU  - Ribò M
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Gramegna, Laura Ludovica
AU  - Gramegna LL
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - IRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy.
FAU - Melendez, Fernando
AU  - Melendez F
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Rosati, Santiago
AU  - Rosati S
AD  - Department of Radiology, Clinical San Carlos Hospital, Madrid, Spain.
FAU - Moreu, Manuel
AU  - Moreu M
AD  - Department of Radiology, Clinical San Carlos Hospital, Madrid, Spain.
FAU - Aixut, Sonia
AU  - Aixut S
AD  - Department of Radiology, L'Hospitalet de Llobregat, Barcelona, Spain.
FAU - Lüttich, Alexandre
AU  - Lüttich A
AD  - Department of Neuroradiology, Hospital Universitario Donostia, San Sebastián, Spain.
FAU - Werner, Mariano
AU  - Werner M
AD  - Department of Radiology, Hospital Clinic I Provincial de Barcelona, Barcelona, 
      Spain.
FAU - Remollo, Sebastian
AU  - Remollo S
AD  - Department of Neurosciences, Universitat Autònoma de Barcelona, Badalona, Spain.
FAU - Quintana, Manuel
AU  - Quintana M
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Coscojuela, Pilar
AU  - Coscojuela P
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Hernandez, David
AU  - Hernandez D
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Dinia, Lavinia
AU  - Dinia L
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Radiology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Lopez-Rueda, Antonio
AU  - Lopez-Rueda A
AD  - Department of Radiology, Hospital Clinic I Provincial de Barcelona, Barcelona, 
      Spain.
FAU - Rubiera, Marta
AU  - Rubiera M
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain.
FAU - Rovira, Àlex
AU  - Rovira À
AD  - Vall d'Hebron Research Institute, Vall d'Hebron University Hospital, Barcelona, 
      Spain.
AD  - Section of Neuroradiology and Magnetic Resonance Unit, Vall d'Hebron University 
      Hospital, Barcelona, Spain.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20190509
TA  - Interv Neuroradiol
JT  - Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical 
      procedures and related neurosciences
JID - 9602695
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Angiography, Digital Subtraction/*methods
MH  - Brain Ischemia/*diagnostic imaging/*surgery
MH  - Catheterization
MH  - Cerebral Angiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neurosurgical Procedures/*methods
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Stents
MH  - Stroke/*diagnostic imaging/*surgery
MH  - Thrombectomy/*methods
MH  - Thrombolytic Therapy
MH  - Treatment Outcome
MH  - Young Adult
PMC - PMC6777112
OTO - NOTNLM
OT  - Stroke
OT  - angiography
OT  - aspiration catheter
OT  - mechanical thrombectomy
OT  - stent retriever
EDAT- 2019/05/11 06:00
MHDA- 2020/02/28 06:00
PMCR- 2020/10/01
CRDT- 2019/05/11 06:00
PHST- 2020/10/01 00:00 [pmc-release]
PHST- 2019/05/11 06:00 [pubmed]
PHST- 2020/02/28 06:00 [medline]
PHST- 2019/05/11 06:00 [entrez]
AID - 10.1177_1591019919847623 [pii]
AID - 10.1177/1591019919847623 [doi]
PST - ppublish
SO  - Interv Neuroradiol. 2019 Oct;25(5):491-496. doi: 10.1177/1591019919847623. Epub 2019 
      May 9.

PMID- 29650784
OWN - NLM
STAT- MEDLINE
DCOM- 20190729
LR  - 20190729
IS  - 1936-959X (Electronic)
IS  - 0195-6108 (Linking)
VI  - 39
IP  - 5
DP  - 2018 May
TI  - Under Pressure: Comparison of Aspiration Techniques for Endovascular Mechanical 
      Thrombectomy.
PG  - 905-909
LID - 10.3174/ajnr.A5605 [doi]
AB  - BACKGROUND AND PURPOSE: Blood flow should be interrupted during mechanical 
      thrombectomy to prevent embolization of clot fragments. The purpose of our study was 
      to provide a handy overview of the most common aspiration devices and to quantify 
      their flow characteristics. MATERIALS AND METHODS: We assessed volumetric flow rates 
      generated by a 60-mL VacLok vacuum pressure syringe, a Pump MAX aspiration pump, and 
      a Dominant Flex suction pump connected to the following: 1) an 8F long sheath, 2) an 
      8F balloon-guide catheter, 3) an ACE 64 distal aspiration catheter, and 4) an AXS 
      Catalyst 6 Distal Access Catheter. We used a water/glycerol solution, which was kept 
      at a constant temperature of 20°C (viscosity, 3.7 mPa · s). RESULTS: Aspiration with 
      the syringe and the Dominant Flex suction pump achieved the highest flows, whereas 
      aspiration with the Pump MAX was significantly lower (P < .001). Resistors in the 
      aspiration system (tubing, connectors, and so forth) restricted flows, especially 
      when the resistance of the catheter was small (due to its large diameter) and the 
      connected resistors became the predominant resistance (P < .001). The syringe 
      achieved an average vacuum pressure of -90 kPa, and the resulting flow was constant 
      during almost the entire procedure of filling the syringe. CONCLUSIONS: 
      Sixty-milliliter VacLok vacuum pressure syringes and the Dominant Flex suction pump 
      achieved high and constant flows likely sufficient to reverse blood flow during 
      thrombectomy with an 8F sheath or balloon-guide catheter in the ICA and modern 
      distal aspiration catheters in the MCA. The Pump MAX aspiration pump is dedicated 
      for use with distal aspiration catheters and is unlikely to reverse blood flow in 
      the ICA and MCA without balloon protection.
CI  - © 2018 by American Journal of Neuroradiology.
FAU - Nikoubashman, O
AU  - Nikoubashman O
AUID- ORCID: 0000-0002-2055-4217
AD  - From the Department of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., M.W.), RWTH Aachen University Hospital, Aachen, Germany 
      onikoubashman@ukaachen.de.
FAU - Wischer, D
AU  - Wischer D
AUID- ORCID: 0000-0002-7787-2101
AD  - From the Department of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., M.W.), RWTH Aachen University Hospital, Aachen, Germany.
FAU - Hennemann, H M
AU  - Hennemann HM
AUID- ORCID: 0000-0002-9175-972X
AD  - From the Department of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., M.W.), RWTH Aachen University Hospital, Aachen, Germany.
FAU - Büsen, M
AU  - Büsen M
AUID- ORCID: 0000-0001-9758-2892
AD  - Institute of Applied Medical Engineering (M.B.), RWTH Aachen University, Aachen, 
      Germany.
FAU - Brockmann, C
AU  - Brockmann C
AUID- ORCID: 0000-0002-8405-1889
AD  - Department of Neuroradiology (C.B.), University Medical Centre, Johannes Gutenberg 
      University, Mainz, Germany.
FAU - Wiesmann, M
AU  - Wiesmann M
AUID- ORCID: 0000-0002-8261-5513
AD  - From the Department of Diagnostic and Interventional Neuroradiology (O.N., D.W., 
      H.M.H., M.W.), RWTH Aachen University Hospital, Aachen, Germany.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180412
PL  - United States
TA  - AJNR Am J Neuroradiol
JT  - AJNR. American journal of neuroradiology
JID - 8003708
MH  - Catheters
MH  - Endovascular Procedures
MH  - Humans
MH  - Models, Biological
MH  - Suction/*instrumentation/*methods
MH  - Syringes
MH  - Thrombectomy/*instrumentation/*methods
EDAT- 2018/04/14 06:00
MHDA- 2019/07/30 06:00
CRDT- 2018/04/14 06:00
PHST- 2017/09/20 00:00 [received]
PHST- 2018/01/31 00:00 [accepted]
PHST- 2018/04/14 06:00 [pubmed]
PHST- 2019/07/30 06:00 [medline]
PHST- 2018/04/14 06:00 [entrez]
AID - ajnr.A5605 [pii]
AID - 10.3174/ajnr.A5605 [doi]
PST - ppublish
SO  - AJNR Am J Neuroradiol. 2018 May;39(5):905-909. doi: 10.3174/ajnr.A5605. Epub 2018 
      Apr 12.

PMID- 30579014
OWN - NLM
STAT- MEDLINE
DCOM- 20190401
LR  - 20191210
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 123
DP  - 2019 Mar
TI  - Increased Success of Single-Pass Large Vessel Recanalization Using a Combined 
      Stentriever and Aspiration Technique: A Single Institution Study.
PG  - e747-e752
LID - S1878-8750(18)32845-6 [pii]
LID - 10.1016/j.wneu.2018.12.023 [doi]
AB  - BACKGROUND: Extensive evidence supports mechanical thrombectomy using stentrievers 
      (SR) for acute large vessel occlusion (aLVO). Aspiration is also used as a first 
      pass or adjunct technique during clot removal. Here we report technical results from 
      mechanical thrombectomy cases using SR alone, aspiration alone (AD), or a 
      combination of SR and aspiration (SA) as a first pass for aLVO. METHODS: An 
      institutional stroke database was reviewed for patients presenting to a single 
      academic institution with anterior circulation aLVO and who were treated with 
      mechanical thrombectomy from 2011 to 2017. Patients managed with SR alone, AD, or a 
      combination of these 2 techniques (SA) were identified. The rate of successful 
      recanalization after the first thrombectomy attempt was compared between the 3 
      groups. RESULTS: A total of 353 patients were analyzed, including 215 in SR, 32 in 
      AD, and 106 in SA groups. There was no significant difference for age and admission 
      National Institutes of Health Stroke Scale between the groups. Successful 
      recanalization rates after the first pass were 35.8% in the SR group, 34.4% in 
      aspiration as a first pass technique, and 55.7% in SA, with a statistically 
      significant higher rate of first pass success in the SA group (P = 0.002). Using 
      balloon-guide catheter doubled the rate of successful first pass recanalization from 
      21.3% to 41.6% in the SR group (P = 0.005); however, the SA technique was more 
      effective for first pass recanalization when compared with an SR and balloon-guide 
      catheter combination (55.7% vs. 41.6%, P = 0.025). CONCLUSIONS: The combination of 
      SR and catheter aspiration can increase the rate of single pass successful 
      recanalization compared with these techniques individually.
CI  - Copyright © 2018 Elsevier Inc. All rights reserved.
FAU - Colby, Geoffrey P
AU  - Colby GP
AD  - Department of Neurosurgery, University of California, Los Angeles, California, USA; 
      Department of Radiology, University of California, Los Angeles, California, USA. 
      Electronic address: gcolby@mednet.ucla.edu.
FAU - Baharvahdat, Humain
AU  - Baharvahdat H
AD  - Department of Neurosurgery, University of California, Los Angeles, California, USA.
FAU - Mowla, Ashkan
AU  - Mowla A
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Young, Richard
AU  - Young R
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Shwe, Yamin
AU  - Shwe Y
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Jahan, Reza
AU  - Jahan R
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Tateshima, Satoshi
AU  - Tateshima S
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Szeder, Viktor
AU  - Szeder V
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Nour, May
AU  - Nour M
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Vinuela, Fernando
AU  - Vinuela F
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
FAU - Duckwiler, Gary
AU  - Duckwiler G
AD  - Department of Radiology, University of California, Los Angeles, California, USA.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20181219
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Brain Ischemia/therapy
MH  - Cerebral Arteries
MH  - Cerebral Revascularization/*instrumentation/methods
MH  - Female
MH  - Humans
MH  - Intracranial Thrombosis/*therapy
MH  - Male
MH  - Mechanical Thrombolysis/*instrumentation/methods
MH  - Retrospective Studies
MH  - Stroke/*therapy
MH  - Surgical Instruments
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Aspiration
OT  - Large vessel occlusion
OT  - Mechanical thrombectomy
OT  - Recanalization
OT  - Solumbra
OT  - Stent retriever
OT  - Stentrieval
EDAT- 2018/12/24 06:00
MHDA- 2019/04/02 06:00
CRDT- 2018/12/23 06:00
PHST- 2018/10/01 00:00 [received]
PHST- 2018/12/05 00:00 [revised]
PHST- 2018/12/07 00:00 [accepted]
PHST- 2018/12/24 06:00 [pubmed]
PHST- 2019/04/02 06:00 [medline]
PHST- 2018/12/23 06:00 [entrez]
AID - S1878-8750(18)32845-6 [pii]
AID - 10.1016/j.wneu.2018.12.023 [doi]
PST - ppublish
SO  - World Neurosurg. 2019 Mar;123:e747-e752. doi: 10.1016/j.wneu.2018.12.023. Epub 2018 
      Dec 19.

PMID- 32447614
OWN - NLM
STAT- Publisher
LR  - 20200524
IS  - 1868-601X (Electronic)
IS  - 1868-4483 (Linking)
DP  - 2020 May 23
TI  - Predictors of Successful First-Pass Thrombectomy with a Balloon Guide Catheter: 
      Results of a Decision Tree Analysis.
LID - 10.1007/s12975-020-00784-2 [doi]
AB  - Complete recanalization after a single retrieval maneuver is an interventional goal 
      in acute ischemic stroke and an independent factor for good clinical outcome. 
      Anatomical biomarkers for predicting clot removal difficulties have not been 
      comprehensively analyzed and await unused. We retrospectively evaluated 200 
      consecutive patients who suffered acute stroke and occlusion of the anterior 
      circulation and were treated with mechanical thrombectomy through a balloon guide 
      catheter (BGC). The primary objective was to evaluate the influence of carotid 
      tortuosity and BGC positioning on the one-pass Modified Thrombolysis in Cerebral 
      Infarction Scale (mTICI) 3 rate, and secondarily, the influence of communicating 
      arteries on the angiographic results. After the first-pass mTICI 3, recanalization 
      fell from 51 to 13%. The regression models and decision tree (supervised machine 
      learning) results concurred: carotid tortuosity was the main constraint on efficacy, 
      reducing the likelihood of mTICI 3 after one pass to 30%. BGC positioning was 
      relevant only in carotid arteries without elongation: BGCs located in the distal 
      internal carotid artery (ICA) had a 70% probability of complete recanalization after 
      one pass, dropping to 43% if located in the proximal ICA. These findings demonstrate 
      that first-pass mTICI 3 is influenced by anatomical and interventional factors 
      capable of being anticipated, enabling the BGC technique to be adapted to patient's 
      anatomy to enhance effectivity.
FAU - Velasco Gonzalez, Aglaé
AU  - Velasco Gonzalez A
AUID- ORCID: 0000-0001-6865-6864
AD  - Department of Clinical Radiology, Institute of Clinical Radiology and 
      Neuroradiology, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 
      Building A1, 48149, Muenster, Germany. Aglae.VelascoGonzalez@ukmuenster.de.
FAU - Görlich, Dennis
AU  - Görlich D
AD  - Institute of Biostatistics and Clinical Research, University of Muenster, 
      Schmeddingstraße 56, 48149, Muenster, Germany.
FAU - Buerke, Boris
AU  - Buerke B
AD  - Department of Clinical Radiology, Institute of Clinical Radiology and 
      Neuroradiology, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 
      Building A1, 48149, Muenster, Germany.
FAU - Münnich, Nico
AU  - Münnich N
AD  - Department of Clinical Radiology, Institute of Clinical Radiology and 
      Neuroradiology, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 
      Building A1, 48149, Muenster, Germany.
FAU - Sauerland, Cristina
AU  - Sauerland C
AD  - Institute of Biostatistics and Clinical Research, University of Muenster, 
      Schmeddingstraße 56, 48149, Muenster, Germany.
FAU - Rusche, Thilo
AU  - Rusche T
AD  - Department of Clinical Radiology, Institute of Clinical Radiology and 
      Neuroradiology, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 
      Building A1, 48149, Muenster, Germany.
FAU - Faldum, Andreas
AU  - Faldum A
AD  - Institute of Biostatistics and Clinical Research, University of Muenster, 
      Schmeddingstraße 56, 48149, Muenster, Germany.
FAU - Heindel, Walter
AU  - Heindel W
AD  - Department of Clinical Radiology, Institute of Clinical Radiology and 
      Neuroradiology, University Hospital of Muenster, Albert-Schweitzer-Campus 1, 
      Building A1, 48149, Muenster, Germany.
LA  - eng
PT  - Journal Article
DEP - 20200523
PL  - United States
TA  - Transl Stroke Res
JT  - Translational stroke research
JID - 101517297
SB  - IM
OTO - NOTNLM
OT  - Carotid arteries
OT  - Circle of Willis
OT  - Stroke
OT  - Suction
OT  - Thrombectomy
EDAT- 2020/05/25 06:00
MHDA- 2020/05/25 06:00
CRDT- 2020/05/25 06:00
PHST- 2019/10/09 00:00 [received]
PHST- 2020/01/28 00:00 [accepted]
PHST- 2020/01/13 00:00 [revised]
PHST- 2020/05/25 06:00 [entrez]
PHST- 2020/05/25 06:00 [pubmed]
PHST- 2020/05/25 06:00 [medline]
AID - 10.1007/s12975-020-00784-2 [pii]
AID - 10.1007/s12975-020-00784-2 [doi]
PST - aheadofprint
SO  - Transl Stroke Res. 2020 May 23. doi: 10.1007/s12975-020-00784-2.

PMID- 16961148
OWN - NLM
STAT- MEDLINE
DCOM- 20060926
LR  - 20121115
IS  - 0022-3085 (Print)
IS  - 0022-3085 (Linking)
VI  - 105
IP  - 3
DP  - 2006 Sep
TI  - Retrograde suction decompression of giant paraclinoid aneurysms using a No. 7 French 
      balloon-containing guide catheter. Technical note.
PG  - 479-81
AB  - The treatment of large and giant paraclinoid carotid artery (CA) aneurysms often 
      requires the use of suction decompression for safe and effective occlusion. Both 
      open and endovascular suction decompression techniques have been described 
      previously. In this article the authors describe a revised endovascular suction 
      decompression technique that provides several advantages in the treatment of large 
      and giant paraclinoid and CA aneurysms. A 51-year-old woman presented with a 
      relatively brief history of progressive visual loss in the right eye, nonspecific 
      headache, and an afferent pupillary defect. After angiography studies had been 
      obtained, it was determined that she had a giant right paraclinoid internal CA 
      aneurysm with a dome size of approximately 26 mm on the right and a neck diameter of 
      10 mm. A modified technique was performed in which suction decompression was used. 
      With the aid of a No. 7 French Concentric balloon guide catheter (Concentric 
      Medical, Inc., Mountain View, CA) and application of a temporary clip distal to the 
      aneurysm, the aneurysm was trapped and decompressed using retrograde suction through 
      the guide catheter when the balloon was inflated. After satisfactory placement of 
      three permanent clips, an intraoperative angiogram obtained through the same guide 
      catheter confirmed CA patency. The aneurysm was then punctured and aspirated, 
      ensuring complete occlusion of the aneurysm sac and reconstruction of the parent 
      vessel. The patient made an excellent recovery and did not suffer any complications. 
      She did not experience worsening in her vision. This technical modification to 
      endovascular suction decompression allows several potential advantages, including 
      higher volume decompression and the ability to deliver endovascular devices to 
      distal arterial locations.
FAU - Parkinson, Richard J
AU  - Parkinson RJ
AD  - Department of Neurological Surgery, Northwestern University, Feinberg School of 
      Medicine, Chicago, Illinois 60611, USA.
FAU - Bendok, Bernard R
AU  - Bendok BR
FAU - Getch, Christopher C
AU  - Getch CC
FAU - Yashar, Parham
AU  - Yashar P
FAU - Shaibani, Ali
AU  - Shaibani A
FAU - Ankenbrandt, William
AU  - Ankenbrandt W
FAU - Awad, Issam A
AU  - Awad IA
FAU - Batjer, H Hunt
AU  - Batjer HH
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Neurosurg
JT  - Journal of neurosurgery
JID - 0253357
SB  - AIM
SB  - IM
MH  - Carotid Artery Diseases/*surgery
MH  - Carotid Artery, Internal
MH  - Catheterization/*instrumentation/methods
MH  - Decompression, Surgical/*instrumentation/methods
MH  - Female
MH  - Humans
MH  - Intracranial Aneurysm/*surgery
MH  - Middle Aged
MH  - Suction/instrumentation
EDAT- 2006/09/12 09:00
MHDA- 2006/09/27 09:00
CRDT- 2006/09/12 09:00
PHST- 2006/09/12 09:00 [pubmed]
PHST- 2006/09/27 09:00 [medline]
PHST- 2006/09/12 09:00 [entrez]
AID - 10.3171/jns.2006.105.3.479 [doi]
PST - ppublish
SO  - J Neurosurg. 2006 Sep;105(3):479-81. doi: 10.3171/jns.2006.105.3.479.

PMID- 31239220
OWN - NLM
STAT- MEDLINE
DCOM- 20190902
LR  - 20190902
IS  - 1532-8511 (Electronic)
IS  - 1052-3057 (Linking)
VI  - 28
IP  - 9
DP  - 2019 Sep
TI  - Evaluation of the Intracranial Flow Alteration during Manual Syringe and Continuous 
      Pump Aspiration.
PG  - 2574-2579
LID - S1052-3057(19)30235-6 [pii]
LID - 10.1016/j.jstrokecerebrovasdis.2019.05.015 [doi]
AB  - GOALS: While mechanical thrombectomy (MT) has been shown to be effective in the 
      treatment of acute large vessel occlusions, adjunctive measures, such as balloon 
      guide catheters (BGC) and aspiration techniques, are utilized heterogeneously. 
      Clarifying the effects of aspiration applied to the anterior cerebral circulation 
      with proximal flow arrest can shed light on embolic protection during MT. MATERIALS 
      AND METHODS: Manual and pump aspiration were applied through a BGC in a synthetic 
      cerebrovascular model with a 60 ml syringe and a Penumbra pump, respectively. Flow 
      direction was observed during the procedure with fluorescent particles and 
      ultraviolet light. Flow rates were monitored at the simulated internal carotid 
      artery and middle cerebral artery (MCA). FINDINGS: Both aspiration methods produced 
      retrograde flow in all the modeled cerebrovascular segments. In the syringe 
      aspiration methods, an interval phase occurred during the experimental trial in 
      which suction forces paused and MCA flow became anterograde through posterior 
      communication artery collateral circulation. CONCLUSION: Flow patterns vary with 
      different methods of aspiration. With proximal flow arrest, continuous aspiration 
      methods induce constant retrograde flow in all vessels, whereas manual aspiration 
      demonstrates various flow changes, including periods of anterograde flow during the 
      procedure, which may be less effective at distal re-embolization prevention.
CI  - Copyright © 2019. Published by Elsevier Inc.
FAU - Okada, Hideo
AU  - Okada H
AD  - Department of Neurological Surgery, Rush University Medical Center, Chicago, 
      Illinois; Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama City, Japan. 
      Electronic address: hide829@me.com.
FAU - Matsuda, Yoshikazu
AU  - Matsuda Y
AD  - Department of Neurological Surgery, Rush University Medical Center, Chicago, 
      Illinois; Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama City, Japan. 
      Electronic address: ymatsuda0517@yahoo.co.jp.
FAU - Malisch, Alex
AU  - Malisch A
AD  - Department of Neurological Surgery, Rush University Medical Center, Chicago, 
      Illinois. Electronic address: amalisch@luc.edu.
FAU - Chung, Joonho
AU  - Chung J
AD  - Department of Neurological Surgery, Rush University Medical Center, Chicago, 
      Illinois; Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University 
      College of Medicine, Seoul, Republic of Korea; Severance Institute for Vascular and 
      Metabolic Research, Yonsei University College of Medicine, Seoul, Republic of Korea. 
      Electronic address: ns.joonho.chung@gmail.com.
FAU - Heiferman, Daniel M
AU  - Heiferman DM
AD  - Department of Neurological Surgery, Loyola University Stritch School of Medicine, 
      Maywood, Illinois. Electronic address: dheiferman@lumc.edu.
FAU - Lopes, Demetrius K
AU  - Lopes DK
AD  - Department of Neurological Surgery, Advocate Health, Park Ridge, Illinois. 
      Electronic address: brainaneurysm@me.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20190622
PL  - United States
TA  - J Stroke Cerebrovasc Dis
JT  - Journal of stroke and cerebrovascular diseases : the official journal of National 
      Stroke Association
JID - 9111633
SB  - IM
MH  - Blood Flow Velocity
MH  - Carotid Artery, Internal/*physiopathology
MH  - *Cerebrovascular Circulation
MH  - Cerebrovascular Disorders/physiopathology/*therapy
MH  - Humans
MH  - Intracranial Embolism/etiology/physiopathology/prevention & control
MH  - Middle Cerebral Artery/*physiopathology
MH  - Models, Anatomic
MH  - Risk Factors
MH  - Suction
MH  - Syringes
MH  - Thrombectomy/adverse effects/instrumentation/*methods
MH  - Time Factors
MH  - Vascular Access Devices
OTO - NOTNLM
OT  - Balloon guide catheter
OT  - aspiration
OT  - mechanical thrombectomy
OT  - stroke
EDAT- 2019/06/27 06:00
MHDA- 2019/09/03 06:00
CRDT- 2019/06/27 06:00
PHST- 2018/11/20 00:00 [received]
PHST- 2019/04/14 00:00 [revised]
PHST- 2019/05/14 00:00 [accepted]
PHST- 2019/06/27 06:00 [pubmed]
PHST- 2019/09/03 06:00 [medline]
PHST- 2019/06/27 06:00 [entrez]
AID - S1052-3057(19)30235-6 [pii]
AID - 10.1016/j.jstrokecerebrovasdis.2019.05.015 [doi]
PST - ppublish
SO  - J Stroke Cerebrovasc Dis. 2019 Sep;28(9):2574-2579. doi: 
      10.1016/j.jstrokecerebrovasdis.2019.05.015. Epub 2019 Jun 22.

PMID- 28366058
OWN - NLM
STAT- MEDLINE
DCOM- 20170424
LR  - 20170424
IS  - 1092-0684 (Electronic)
IS  - 1092-0684 (Linking)
VI  - 42
IP  - 4
DP  - 2017 Apr
TI  - Novel and emerging technologies for endovascular thrombectomy.
PG  - E12
LID - 10.3171/2017.1.FOCUS16518 [doi]
AB  - Endovascular thrombectomy device improvements in recent years have served a pivotal 
      role in improving the success and safety of the thrombectomy procedure. As the 
      intervention gains widespread use, developers have focused on maximizing the 
      reperfusion rates and reducing procedural complications associated with these 
      devices. This has led to a boom in device development. This review will cover novel 
      and emerging technologies developed for endovascular thrombectomy.
FAU - Chartrain, Alexander G
AU  - Chartrain AG
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Awad, Ahmed J
AU  - Awad AJ
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Mascitelli, Justin R
AU  - Mascitelli JR
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Shoirah, Hazem
AU  - Shoirah H
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Oxley, Thomas J
AU  - Oxley TJ
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Feng, Rui
AU  - Feng R
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Gallitto, Matthew
AU  - Gallitto M
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - De Leacy, Reade
AU  - De Leacy R
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Fifi, Johanna T
AU  - Fifi JT
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
FAU - Kellner, Christopher P
AU  - Kellner CP
AD  - Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New 
      York.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Neurosurg Focus
JT  - Neurosurgical focus
JID - 100896471
SB  - IM
MH  - Brain Ischemia/complications
MH  - Endovascular Procedures/*methods
MH  - Humans
MH  - *Medical Laboratory Personnel
MH  - Stroke/etiology/*therapy
MH  - Thrombectomy/*instrumentation/*methods
OTO - NOTNLM
OT  - *ADAPT = A Direct Aspiration First Pass Technique
OT  - *BGC = balloon guide catheter
OT  - *ERIC = Embolus Retriever with Interlinked Cages
OT  - *ICH = intracerebral hemorrhage
OT  - *ID = inner diameter
OT  - *LVO = large vessel occlusion
OT  - *OD = outer diameter
OT  - *TICI = Thrombolysis in Cerebral Infarction
OT  - *acute ischemic stroke
OT  - *aspiration catheter
OT  - *endovascular thrombectomy
OT  - *large vessel occlusion
OT  - *mRS = modified Rankin Scale
OT  - *stent retriever
EDAT- 2017/04/04 06:00
MHDA- 2017/04/25 06:00
CRDT- 2017/04/04 06:00
PHST- 2017/04/04 06:00 [entrez]
PHST- 2017/04/04 06:00 [pubmed]
PHST- 2017/04/25 06:00 [medline]
AID - 10.3171/2017.1.FOCUS16518 [doi]
PST - ppublish
SO  - Neurosurg Focus. 2017 Apr;42(4):E12. doi: 10.3171/2017.1.FOCUS16518.

PMID- 23493730
OWN - NLM
STAT- MEDLINE
DCOM- 20130625
LR  - 20161122
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 44
IP  - 5
DP  - 2013 May
TI  - Reduction in distal emboli with proximal flow control during mechanical 
      thrombectomy: a quantitative in vitro study.
PG  - 1396-401
LID - 10.1161/STROKEAHA.111.670463 [doi]
AB  - BACKGROUND AND PURPOSE: To evaluate the impact of proximal flow control on efficacy 
      and safety of mechanical thrombectomy in an in vitro middle cerebral artery 
      occlusion. METHODS: Three independent variables, including clot type, device (Merci 
      Retriever, Solitaire FR, and Trevo devices), and use of a balloon guide catheter, 
      were used to ascertain the impact of proximal flow control on the size and number of 
      distal emboli generated during thrombectomy. Secondary end points were the 
      recanalization rate and amount of flow restored. RESULTS: Use of the balloon guide 
      catheter during thrombectomy of the fragile, hard clot significantly reduced the 
      formation of large distal emboli with a diameter >1 mm, regardless of the device 
      used (P<0.01). Applying aspiration via the balloon guide catheter in place of the 
      conventional guide catheter resulted in a significant increase of flow reversal 
      (P<0.0001). Prior to thrombectomy, deployment of the stent-trievers produced 
      immediate flow restoration through the soft and hard clot occlusions, 69.2 ± 27.3 
      and 45.5 ± 22.8 mL/min, respectively, that was preserved after the balloon inflation 
      because of collateral flow via the posterior communication artery. After deployment 
      but before thrombectomy, no flow was restored when using the Merci Retriever. After 
      thrombectomy, complete flow restoration was achieved in a majority of cases. The 
      Merci Retriever required more thrombectomy attempts to achieve hard clot removal 
      compared with the stent-trievers when the conventional guide catheter was used (1.5 
      versus 1.1). CONCLUSIONS: The risk of distal embolization was significantly reduced 
      with the use of the balloon guide catheter.
FAU - Chueh, Ju-Yu
AU  - Chueh JY
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts, Worcester, MA, USA.
FAU - Kühn, Anna Luisa
AU  - Kühn AL
FAU - Puri, Ajit S
AU  - Puri AS
FAU - Wilson, Scott D
AU  - Wilson SD
FAU - Wakhloo, Ajay K
AU  - Wakhloo AK
FAU - Gounis, Matthew J
AU  - Gounis MJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130314
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
MH  - Catheterization
MH  - Humans
MH  - Infarction, Middle Cerebral Artery/*surgery
MH  - *Models, Anatomic
MH  - Stents
MH  - Stroke/*surgery
MH  - Thrombectomy/instrumentation/*methods
MH  - Treatment Outcome
EDAT- 2013/03/16 06:00
MHDA- 2013/06/26 06:00
CRDT- 2013/03/16 06:00
PHST- 2013/03/16 06:00 [entrez]
PHST- 2013/03/16 06:00 [pubmed]
PHST- 2013/06/26 06:00 [medline]
AID - STROKEAHA.111.670463 [pii]
AID - 10.1161/STROKEAHA.111.670463 [doi]
PST - ppublish
SO  - Stroke. 2013 May;44(5):1396-401. doi: 10.1161/STROKEAHA.111.670463. Epub 2013 Mar 
      14.

PMID- 25376809
OWN - NLM
STAT- MEDLINE
DCOM- 20151201
LR  - 20181202
IS  - 1936-959X (Electronic)
IS  - 0195-6108 (Linking)
VI  - 36
IP  - 3
DP  - 2015 Mar
TI  - Comparison of modern stroke thrombectomy approaches using an in vitro 
      cerebrovascular occlusion model.
PG  - 547-51
LID - 10.3174/ajnr.A4149 [doi]
AB  - BACKGROUND AND PURPOSE: A new in vitro cerebrovascular occlusion model of the 
      intracranial circulation was developed recently for testing thrombectomy devices. 
      Using this model, we compared recanalization success associated with different 
      modern endovascular thrombectomy approaches. MATERIALS AND METHODS: Model 
      experiments were performed in 4 thrombectomy test groups: 1) primary or direct 
      Stentriever thrombectomy with a conventional guide catheter (control group), 2) 
      primary Stentriever thrombectomy with a balloon-guide catheter, 3) combined 
      Stentriever-continuous aspiration approach, and 4) direct aspiration alone. 
      Successful recanalization was defined as a TICI score of 2b or 3. RESULTS: 
      Seventy-one thrombectomy experiments were conducted. Similar rates of TICI 2b-3 
      scores were achieved with balloon-guide and conventional guide catheters (P = .34). 
      The combined Stentriever plus aspiration approach and the primary aspiration 
      thrombectomy resulted in significantly higher rates of TICI 2b or 3 than the 
      conventional guide-catheter approach in the control group (P = .008 and P = .0001, 
      respectively). The primary Stentriever thrombectomy with the conventional guide 
      catheter showed the highest rate of embolization to new territories (53%). 
      CONCLUSIONS: Data from our in vitro model experiments show that the Stentriever 
      thrombectomy under continuous aspiration and primary aspiration thrombectomy 
      approaches led to the highest degree of recanalization.
CI  - © 2015 by American Journal of Neuroradiology.
FAU - Mokin, M
AU  - Mokin M
AD  - From the Departments of Neurosurgery (M.M., E.I.L., A.H.S.).
FAU - Setlur Nagesh, S V
AU  - Setlur Nagesh SV
AD  - Biomedical Engineering (S.V.S.N., C.N.I.) Electrical Engineering (S.V.S.N.) 
      Mechanical and Aerospace Engineering (S.V.S.N.).
FAU - Ionita, C N
AU  - Ionita CN
AD  - Biomedical Engineering (S.V.S.N., C.N.I.) Toshiba Stroke and Vascular Research 
      Center (C.N.I., E.I.L., A.H.S.), University at Buffalo, State University of New 
      York, Buffalo, New York.
FAU - Levy, E I
AU  - Levy EI
AD  - From the Departments of Neurosurgery (M.M., E.I.L., A.H.S.) Radiology (E.I.L., 
      A.H.S.) Toshiba Stroke and Vascular Research Center (C.N.I., E.I.L., A.H.S.), 
      University at Buffalo, State University of New York, Buffalo, New York.
FAU - Siddiqui, A H
AU  - Siddiqui AH
AD  - From the Departments of Neurosurgery (M.M., E.I.L., A.H.S.) Radiology (E.I.L., 
      A.H.S.) Toshiba Stroke and Vascular Research Center (C.N.I., E.I.L., A.H.S.), 
      University at Buffalo, State University of New York, Buffalo, New York Jacobs 
      Institute (A.H.S.), Buffalo, New York. asiddiqui@ubns.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20141106
PL  - United States
TA  - AJNR Am J Neuroradiol
JT  - AJNR. American journal of neuroradiology
JID - 8003708
SB  - IM
MH  - Female
MH  - Humans
MH  - Intracranial Thrombosis/*surgery
MH  - Stroke/*surgery
MH  - Thrombectomy/instrumentation/*methods
MH  - Treatment Outcome
EDAT- 2014/11/08 06:00
MHDA- 2015/12/15 06:00
CRDT- 2014/11/08 06:00
PHST- 2014/11/08 06:00 [entrez]
PHST- 2014/11/08 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - ajnr.A4149 [pii]
AID - 10.3174/ajnr.A4149 [doi]
PST - ppublish
SO  - AJNR Am J Neuroradiol. 2015 Mar;36(3):547-51. doi: 10.3174/ajnr.A4149. Epub 2014 Nov 
      6.

PMID- 29578080
OWN - NLM
STAT- MEDLINE
DCOM- 20180607
LR  - 20181202
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 114
DP  - 2018 Jun
TI  - Endovascular Retrograde Suction Decompression-Assisted Clipping of Large Paraclinoid 
      Aneurysm in Hybrid Operating Room: 2-Dimensional Operative Video.
PG  - 178
LID - S1878-8750(18)30591-6 [pii]
LID - 10.1016/j.wneu.2018.03.109 [doi]
AB  - Surgical treatment of large paraclinoid aneurysms remains technically challenging 
      due to the adjacent bony anatomy and neurovascular structures. Endovascular 
      retrograde suction decompression using a double-lumen balloon catheter facilitates 
      clip ligation of the aneurysm. Video 1 demonstrates a large paraclinoid aneurysm 
      that was treated with endovascular balloon occlusion and retrograde suction 
      decompression in a hybrid operating room. A 49-year-old woman presented with 
      progressively worsening headache. Computed tomography angiography demonstrated a 
      large 16-mm left paraclinoid aneurysm. Neurologic examination showed no deficits. 
      Angiography with compression of the left carotid artery showed the collateral blood 
      flow through the posterior communicating artery. The aneurysm was exposed via the 
      pterional transsylvian approach. A double-lumen balloon guide catheter was placed in 
      the left internal carotid artery. Considering the risk of ischemic complications, 
      the "trapping-evacuation" technique was not used. After balloon inflation, a 
      temporary clip was placed on the posterior communicating artery. Retrograde suction 
      through the guide catheter decreased the intra-aneurysmal pressure. Tandem clipping 
      with fenestrated clips was used to occlude the aneurysm and reconstruct the parent 
      artery. Postoperative angiography confirmed complete obliteration of the aneurysm, 
      and the patient recovered without any neurologic deficits. Endovascular balloon 
      occlusion obviated the need for cervical dissection of the internal carotid artery. 
      Retrograde suction decompression and intraoperative angiography facilitated surgical 
      clipping for large and giant paraclinoid aneurysms.
CI  - Copyright © 2018 Elsevier Inc. All rights reserved.
FAU - Xu, Feng
AU  - Xu F
AD  - Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan 
      University, Shanghai, China. Electronic address: fengxu.dr@gmail.com.
FAU - Huang, Lei
AU  - Huang L
AD  - Department of Radiology, Huashan Hospital, Shanghai Medical College, Fudan 
      University, Shanghai, China.
FAU - Xu, Bin
AU  - Xu B
AD  - Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan 
      University, Shanghai, China.
FAU - Gu, Yuxiang
AU  - Gu Y
AD  - Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan 
      University, Shanghai, China.
FAU - Leng, Bing
AU  - Leng B
AD  - Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan 
      University, Shanghai, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Video-Audio Media
DEP - 20180323
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Decompression, Surgical/*methods
MH  - Endovascular Procedures/*methods
MH  - Female
MH  - Humans
MH  - Intracranial Aneurysm/diagnostic imaging/*surgery
MH  - Middle Aged
MH  - Neurosurgical Procedures/*methods
MH  - Operating Rooms/*methods
MH  - Suction/methods
MH  - Surgical Instruments/statistics & numerical data
MH  - Video-Assisted Surgery/*methods
OTO - NOTNLM
OT  - Clipping
OT  - Endovascular
OT  - Hybrid
OT  - Paraclinoid aneurysm
OT  - Retrograde suction decompression
EDAT- 2018/03/27 06:00
MHDA- 2018/06/08 06:00
CRDT- 2018/03/27 06:00
PHST- 2017/12/22 00:00 [received]
PHST- 2018/03/14 00:00 [revised]
PHST- 2018/03/15 00:00 [accepted]
PHST- 2018/03/27 06:00 [pubmed]
PHST- 2018/06/08 06:00 [medline]
PHST- 2018/03/27 06:00 [entrez]
AID - S1878-8750(18)30591-6 [pii]
AID - 10.1016/j.wneu.2018.03.109 [doi]
PST - ppublish
SO  - World Neurosurg. 2018 Jun;114:178. doi: 10.1016/j.wneu.2018.03.109. Epub 2018 Mar 
      23.

PMID- 30069103
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 0976-3147 (Print)
IS  - 0976-3155 (Electronic)
IS  - 0976-3155 (Linking)
VI  - 9
IP  - 3
DP  - 2018 Jul-Sep
TI  - Arterial Dissection Following the Use of Remote Aspiration Thrombectomy.
PG  - 417-419
LID - 10.4103/jnrp.jnrp_519_17 [doi]
AB  - Remote aspiration thrombectomy using a balloon guide catheter for acute carotid 
      artery occlusion has been proposed as a safe and effective technique. We present a 
      case of iatrogenic arterial dissection of the distal cervical segment in a patient 
      with proximal vessel occlusion who underwent attempted revascularization using this 
      strategy. A 57-year-old male patient presented with computed tomography (CT) 
      angiogram evidence of a left carotid terminus and M1 segment occlusion. The patient 
      was taken emergently for mechanical thrombectomy. Remote aspiration thrombectomy was 
      attempted twice using manual aspiration through a balloon guide catheter in the 
      common carotid artery; however, this resulted in minimal recanalization of the 
      carotid terminus and a new iatrogenic dissection within the internal carotid artery 
      (ICA) just proximal to the skull base. Despite multiple additional attempts at 
      mechanical thrombectomy, only limited recanalization of the ICA terminus and 
      anterior cerebral artery distribution was achieved, with no significant flow past 
      the M1 segment. After the procedure, a large ischemic territory within the left 
      middle cerebral artery distribution consistent with the continued M1 segment 
      occlusion was apparent on CT. The patient died on the poststroke day 6. Although 
      remote aspiration thrombectomy for thromboemboli in this location has potential 
      benefits, it should be used cautiously given the potential risk of injury to the 
      proximal vasculature.
FAU - Kilburg, Craig
AU  - Kilburg C
AD  - Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt 
      Lake City, Utah, USA.
FAU - Kalani, M Yashar S
AU  - Kalani MYS
AD  - Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt 
      Lake City, Utah, USA.
FAU - Park, Min S
AU  - Park MS
AD  - Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt 
      Lake City, Utah, USA.
LA  - eng
PT  - Case Reports
TA  - J Neurosci Rural Pract
JT  - Journal of neurosciences in rural practice
JID - 101533710
PMC - PMC6050781
OTO - NOTNLM
OT  - *Arterial dissection
OT  - *balloon guide catheter
OT  - *carotid artery occlusion
OT  - *remote aspiration thrombectomy
OT  - *thromboembolus
COIS- There are no conflicts of interest.
EDAT- 2018/08/03 06:00
MHDA- 2018/08/03 06:01
CRDT- 2018/08/03 06:00
PHST- 2018/08/03 06:00 [entrez]
PHST- 2018/08/03 06:00 [pubmed]
PHST- 2018/08/03 06:01 [medline]
AID - JNRP-9-417 [pii]
AID - 10.4103/jnrp.jnrp_519_17 [doi]
PST - ppublish
SO  - J Neurosci Rural Pract. 2018 Jul-Sep;9(3):417-419. doi: 10.4103/jnrp.jnrp_519_17.

PMID- 25540180
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20181113
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Print)
IS  - 1759-8478 (Linking)
VI  - 8
IP  - 2
DP  - 2016 Feb
TI  - Risk of distal embolization with stent retriever thrombectomy and ADAPT.
PG  - 197-202
LID - 10.1136/neurintsurg-2014-011491 [doi]
AB  - BACKGROUND: There is a discrepancy in clinical outcomes and the achieved 
      recanalization rates with stent retrievers in the endovascular treatment of ischemic 
      stroke. It is our hypothesis that procedural release of embolic particulate may be 
      one contributor to poor outcomes and is a modifiable risk. The goal of this study is 
      to assess various treatment strategies that reduce the risk of distal emboli. 
      METHODS: Mechanical thrombectomy was simulated in a vascular phantom with collateral 
      circulation. Hard fragment-prone clots (HFC) and soft elastic clots (SECs) were used 
      to generate middle cerebral artery (MCA) occlusions that were retrieved by the 
      Solitaire FR devices through (1) an 8 Fr balloon guide catheter (BGC), (2) a 5 Fr 
      distal access catheter at the proximal aspect of the clot in the MCA (Solumbra), or 
      (3) a 6 Fr guide catheter with the tip at the cervical internal carotid artery 
      (guide catheter, GC). Results from mechanical thrombectomy were compared with those 
      from direct aspiration using the Penumbra 5MAX catheter. The primary endpoint was 
      the size distribution of emboli to the distribution of the middle and anterior 
      cerebral arteries. RESULTS: Solumbra was the most efficient method for reducing HFC 
      fragments (p<0.05) while BGC was the best method for preventing SEC fragmentation 
      (p<0.05). The risk of forming HFC distal emboli (>1000 µm) was significantly 
      increased using GC. A non-statistically significant benefit of direct aspiration was 
      observed in several subgroups of emboli with size 50-1000 µm. However, compared with 
      the stent-retriever mechanical thrombectomy techniques, direct aspiration 
      significantly increased the risk of SEC fragmentation (<50 µm) by at least twofold. 
      CONCLUSIONS: The risk of distal embolization is affected by the catheterization 
      technique and clot mechanics.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/
FAU - Chueh, Ju-Yu
AU  - Chueh JY
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Puri, Ajit S
AU  - Puri AS
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Wakhloo, Ajay K
AU  - Wakhloo AK
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Gounis, Matthew J
AU  - Gounis MJ
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141224
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Device Removal/adverse effects/*methods
MH  - Embolization, Therapeutic/*adverse effects/methods
MH  - Humans
MH  - Risk Factors
MH  - *Stents
MH  - Thrombectomy/*adverse effects/methods
PMC - PMC4752657
OTO - NOTNLM
OT  - Device
OT  - Intervention
OT  - Stroke
OT  - Thrombectomy
EDAT- 2014/12/30 06:00
MHDA- 2016/12/15 06:00
CRDT- 2014/12/26 06:00
PHST- 2014/09/26 00:00 [received]
PHST- 2014/12/01 00:00 [accepted]
PHST- 2014/12/26 06:00 [entrez]
PHST- 2014/12/30 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - neurintsurg-2014-011491 [pii]
AID - 10.1136/neurintsurg-2014-011491 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2016 Feb;8(2):197-202. doi: 10.1136/neurintsurg-2014-011491. 
      Epub 2014 Dec 24.

PMID- 30177546
OWN - NLM
STAT- MEDLINE
DCOM- 20190409
LR  - 20190409
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 11
IP  - 3
DP  - 2019 Mar
TI  - Microcatheter navigation through the clot: does size matter?
PG  - 271-274
LID - 10.1136/neurintsurg-2018-014105 [doi]
AB  - BACKGROUND: Despite high recanalization rates achieved with endovascular treatment 
      of acute ischemic strokes, around 50% of eligible patients will not achieve a good 
      outcome. Parameters that may determine patient outcomes include: time from puncture 
      to recanalization, the collateral status, the anesthesia regimen, blood pressure 
      management, and distal emboli. Characterization of distal emboli generated during 
      mechanical thrombectomy has been performed in previous studies. OBJECTIVE: To 
      further investigate the risk of distal embolization associated with microcatheter 
      navigation across the clot. METHODS: A contrast-enhanced clot analog was used in an 
      in vitro model that mimicked a middle cerebral artery occlusion within a complete 
      circle of Willis vascular replica. The clot was crossed with one of the following 
      microcatheters: Pro18, XT-27 or 3MAX. The emboli generated during the procedure were 
      collected and measured. RESULTS: The use of Pro18 and XT-27 resulted in a 
      significant reduction of visible particles (size ≥500 µm) as compared with the 3MAX 
      catheter (P<0.003). For the size range between 8 and 200 µm, there was a trend for 
      Pro18 to generate fewer particles (-18%) than XT-27 but without statistical 
      significance (P>0.05). In comparison with previously published data, acquired under 
      the same conditions, it was found that the clot crossing maneuver accounts 
      approximately for 12% of the total number of small emboli (<200 µm) induced during a 
      stent retriever-mediated mechanical thrombectomy procedure via a balloon guide 
      catheter. CONCLUSIONS: The clot crossing maneuver has a significant effect on the 
      total number of small particles induced during mechanical thrombectomy. Smaller 
      microcatheter sizes should be favored when possible.
CI  - © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Caroff, Jildaz
AU  - Caroff J
AUID- ORCID: 0000-0002-0029-1835
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
AD  - Department of Interventional Neuroradiology, NEURI Center, Bicêtre Hospital, Clichy, 
      France.
FAU - King, Robert M
AU  - King RM
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Arslanian, Rose
AU  - Arslanian R
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Marosfoi, Miklos
AU  - Marosfoi M
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Langan, Erin T
AU  - Langan ET
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Gounis, Matthew J
AU  - Gounis MJ
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
FAU - Chueh, Ju-Yu
AU  - Chueh JY
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts Medical School, Worcester, Massachusetts, USA.
LA  - eng
PT  - Journal Article
DEP - 20180903
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Catheterization/instrumentation/methods
MH  - *Catheters
MH  - Embolization, Therapeutic/instrumentation/methods
MH  - Humans
MH  - Infarction, Middle Cerebral Artery/*surgery
MH  - *Models, Anatomic
MH  - Neuronavigation/instrumentation/*methods
MH  - Thrombectomy/instrumentation/methods
MH  - Thrombosis/*surgery
OTO - NOTNLM
OT  - catheter
OT  - device
OT  - stroke
COIS- Competing interests: JC has received educational grant from Microvention/Terumo and 
      Medtronic. MM, J-YC: fee-for-service consulting for Stryker Neurovascular, ETL: 
      fee-for-service consulting for Imperative Care, InNeuroCo, Route 92 Medical, 
      StrykerNeurovascular. MJG: as been a consultant on a fee-per-hour basis for 
      Cerenovus, Imperative Care, InNeuroCo, Medtronic Neurovascular, Phenox, Route 92 
      Medical, Stryker Neurovascular; holds stock in InNeuroCo, Imperative Care and 
      Neurogami; and has received research support from the National Institutes of Health 
      (NIH), Anaconda, Cerenovus, Cook Medical, Gentuity, Imperative Care, InNeuroCo, 
      Magneto, Microvention, Medtronic Neurovascular, MIVI Neurosciences, Neuravi, 
      Neurogami, Philips Healthcare, Rapid Medical, Route 92M, Stryker Neurovascular, and 
      the Wyss Institute.
EDAT- 2018/09/05 06:00
MHDA- 2019/04/10 06:00
CRDT- 2018/09/05 06:00
PHST- 2018/05/18 00:00 [received]
PHST- 2018/07/13 00:00 [revised]
PHST- 2018/07/24 00:00 [accepted]
PHST- 2018/09/05 06:00 [pubmed]
PHST- 2019/04/10 06:00 [medline]
PHST- 2018/09/05 06:00 [entrez]
AID - neurintsurg-2018-014105 [pii]
AID - 10.1136/neurintsurg-2018-014105 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2019 Mar;11(3):271-274. doi: 10.1136/neurintsurg-2018-014105. 
      Epub 2018 Sep 3.

PMID- 30410514
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1664-9737 (Print)
IS  - 1664-5545 (Electronic)
IS  - 1664-5545 (Linking)
VI  - 7
IP  - 6
DP  - 2018 Oct
TI  - Active Reperfusion Hemorrhage during Thrombectomy: Angiographic Findings and 
      Real-Time Correlation with the CT "Spot Sign".
PG  - 370-377
LID - 10.1159/000488084 [doi]
AB  - INTRODUCTION: Symptomatic intracranial hemorrhage represents one of the most feared 
      complications of endovascular reperfusion. We aim to describe a series of patients 
      that experienced immediate reperfusion injury with active intraprocedural 
      extravasation within the territory of the deep penetrating arteries and provide 
      real-time correlation with CT "spot sign." METHODS: This was a retrospective 
      analysis of patients that suffered reperfusion injury with active arterial 
      extravasation during endovascular stroke treatment in two tertiary care centers. 
      RESULTS: Five patients were identified. Median age was 63 (58-71) years, 66% were 
      male. Median NIHSS was 13.5 (9.5-23.0), platelet level 212,000 (142,000-235,000), 
      baseline systolic blood pressure 152 (133-201) mm Hg, and non-contrast CT ASPECTS 
      7.0 (6.5-9.0). Two patients were taking aspirin and one had received intravenous 
      thrombolysis. There were three middle cerebral artery M1, one internal carotid 
      artery terminus, and one vertebrobasilar junction occlusion. Three patients had 
      anterior circulation tandem occlusions. Stroke etiology was extracranial 
      atherosclerosis (n = 2), intracranial atherosclerosis (n = 2), and cervical 
      dissection (n = 1). The median time from onset to puncture was 5.5 (3.9-8.6) h. 
      Intravenous heparin was administered in all patients (median dose of 4,750 
      [3,250-6,000] units) and intravenous abciximab in four. All tandem cases had the 
      cervical lesion addressed first. Four lenticulostriates and one paramedian pontine 
      artery were involved. Intraprocedural flat-panel CT was performed in four (80%) 
      cases and provided real-time correlation between the active contrast extravasation 
      and the "spot sign." The bailout included use of protamine, blood pressure control, 
      and balloon guide catheter or intracranial compliant balloon inflation plus coiling 
      of targeted vessel. All patients had angiographic cessation of bleeding at the end 
      of the procedure with parenchymal hemorrhage type 1 in one case and type 2 in four. 
      Three patients had modified Rankin score of 4 and two were dead at 90 days. 
      CONCLUSIONS: Active reperfusion hemorrhage involving perforator arteries was 
      observed to correlate with the CT "spot sign" and to be associated with poor 
      outcomes.
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Emory University School of Medicine/Marcus Stroke & Neuroscience Center - Grady 
      Memorial Hospital, Atlanta, Georgia, USA.
FAU - Ferreira, Ivan M
AU  - Ferreira IM
AD  - Emory University School of Medicine/Marcus Stroke & Neuroscience Center - Grady 
      Memorial Hospital, Atlanta, Georgia, USA.
FAU - Barreira, Clara
AU  - Barreira C
AD  - Emory University School of Medicine/Marcus Stroke & Neuroscience Center - Grady 
      Memorial Hospital, Atlanta, Georgia, USA.
FAU - Grossberg, Jonathan A
AU  - Grossberg JA
AD  - Emory University School of Medicine/Marcus Stroke & Neuroscience Center - Grady 
      Memorial Hospital, Atlanta, Georgia, USA.
FAU - Diana, Francesco
AU  - Diana F
AD  - Hospital Policlinico Umberto I/Sapienza University, Rome, Italy.
FAU - Peschillo, Simone
AU  - Peschillo S
AD  - Hospital Policlinico Umberto I/Sapienza University, Rome, Italy.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Emory University School of Medicine/Marcus Stroke & Neuroscience Center - Grady 
      Memorial Hospital, Atlanta, Georgia, USA.
LA  - eng
PT  - Journal Article
DEP - 20180608
TA  - Interv Neurol
JT  - Interventional neurology
JID - 101606828
PMC - PMC6216709
OTO - NOTNLM
OT  - Hemorrhage
OT  - Reperfusion injury
OT  - Stroke
OT  - Thrombectomy
EDAT- 2018/11/10 06:00
MHDA- 2018/11/10 06:01
CRDT- 2018/11/10 06:00
PHST- 2018/01/08 00:00 [received]
PHST- 2018/03/02 00:00 [accepted]
PHST- 2018/11/10 06:00 [entrez]
PHST- 2018/11/10 06:00 [pubmed]
PHST- 2018/11/10 06:01 [medline]
AID - ine-0007-0370 [pii]
AID - 10.1159/000488084 [doi]
PST - ppublish
SO  - Interv Neurol. 2018 Oct;7(6):370-377. doi: 10.1159/000488084. Epub 2018 Jun 8.

PMID- 29628942
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1664-9737 (Print)
IS  - 1664-5545 (Electronic)
IS  - 1664-5545 (Linking)
VI  - 7
IP  - 1-2
DP  - 2018 Feb
TI  - Clinical and Angiographic Outcomes with the Combined Local Aspiration and Retriever 
      in the North American Solitaire Stent-Retriever Acute Stroke (NASA) Registry.
PG  - 26-35
LID - 10.1159/000480353 [doi]
AB  - BACKGROUND: Various techniques are used to enhance the results of mechanical 
      thrombectomy with stent-retrievers, including proximal arrest with balloon guide 
      catheter (BGC), conventional large bore proximal catheter (CGC), or in combination 
      with local aspiration through a large-bore catheter positioned at the clot interface 
      (Aspiration-Retriever Technique for Stroke [ARTS]). We evaluated the impact of ARTS 
      in the North American Solitaire Acute Stroke (NASA) registry. SUMMARY: Data on the 
      use of the aspiration technique were available for 285 anterior circulation 
      patients, of which 29 underwent ARTS technique, 131 CGC, and 125 BGC. Baseline 
      demographics were comparable, except that ARTS patients are less likely to have 
      hypertension or atrial fibrillation. The ARTS group had more ICA occlusions (41.4 
      vs. 22% in the BGC, p = 0.04 and 26% in CGC, p = 0.1) and less MCA/M1 occlusions 
      (44.8 vs. 68% in BGC and 62% in CGC). Time from arterial puncture to reperfusion or 
      end of procedure with ARTS was shorter than with CGC (54 vs. 91 min, p = 0.001) and 
      was comparable to the BGC time (54 vs. 67, p = 0.11). Final degree of reperfusion 
      was comparable among the groups (TICI [modified Thrombolysis in Cerebral Infarction] 
      score 2b or higher was 72 vs. 70% for CGC vs. 78% for BGC). Procedural 
      complications, mortality, and good clinical outcome at 90 days were similar between 
      the groups. KEY MESSAGES: The ARTS mechanical thrombectomy in acute ischemic stroke 
      patients appears to yield better results as compared to the use of CGCs with no 
      significant difference when compared to BGC. This early ARTS technique NASA registry 
      data are limited by the earlier generation distal large bore catheters and small 
      sample size. Future studies should focus on the comparison of ARTS and BGC 
      techniques.
FAU - Malisch, Tim W
AU  - Malisch TW
AD  - Department of Radiology, Alexian Brothers Medical Center, Elk Grove Village, 
      Illinois, USA.
FAU - Zaidat, Osama O
AU  - Zaidat OO
AD  - St Vincent Mercy Hospital, Toledo, Ohio, USA.
AD  - Neuroscience Center, Well Star Health System, Atlanta, Georgia, USA.
FAU - Castonguay, Alicia C
AU  - Castonguay AC
AD  - St Vincent Mercy Hospital, Toledo, Ohio, USA.
FAU - Marden, Franklin A
AU  - Marden FA
AD  - Department of Radiology, Alexian Brothers Medical Center, Elk Grove Village, 
      Illinois, USA.
FAU - Gupta, Rishi
AU  - Gupta R
AD  - St Vincent Mercy Hospital, Toledo, Ohio, USA.
AD  - Neuroscience Center, Well Star Health System, Atlanta, Georgia, USA.
FAU - Sun, Chung-Huan J
AU  - Sun CJ
AD  - St Vincent Mercy Hospital, Toledo, Ohio, USA.
AD  - Neuroscience Center, Well Star Health System, Atlanta, Georgia, USA.
FAU - Martin, Coleman O
AU  - Martin CO
AD  - Saint Luke's Kansas City, Kansas City, Missouri, USA.
FAU - Holloway, William E
AU  - Holloway WE
AD  - Saint Luke's Kansas City, Kansas City, Missouri, USA.
FAU - Mueller-Kronast, Nils
AU  - Mueller-Kronast N
AD  - Department of Neurology, Delray Medical Center, Delray Beach, Florida, USA.
FAU - English, Joey
AU  - English J
AD  - California Pacific Medical Center, San Francisco, California, USA.
FAU - Linfante, Italo
AU  - Linfante I
AD  - Division of Interventional Neuroradiology, Baptist Cardiac and Vascular Institute, 
      Miami, Florida, USA.
FAU - Dabus, Guilherme
AU  - Dabus G
AD  - Division of Interventional Neuroradiology, Baptist Cardiac and Vascular Institute, 
      Miami, Florida, USA.
FAU - Bozorgchami, Hormozd
AU  - Bozorgchami H
AD  - Oregon Health and Science University, Portland, Oregon, USA.
FAU - Xavier, Andrew
AU  - Xavier A
AD  - Department of Neurology, Wayne State University School of Medicine, Detroit, 
      Michigan, USA.
FAU - Rai, Ansaar T
AU  - Rai AT
AD  - Department of Radiology, West Virginia University Hospital, Morgantown, West 
      Virginia, USA.
FAU - Froehler, Michael
AU  - Froehler M
AD  - Department of Neurology, Neurosurgery, Radiology, Vanderbilt University Medical 
      Center, Nashville, Tennessee, USA.
FAU - Badruddin, Aamir
AU  - Badruddin A
AD  - Provena Saint Joseph Medical Center, Joliet, Illinois, USA.
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - Department of Neurology, Neurosurgery, Radiology, Boston Medical Center, Boston, 
      Massachusetts, USA.
FAU - Taqi, M Asif
AU  - Taqi MA
AD  - Desert Regional Medical Center, Palm Springs, California, USA.
FAU - Abraham, Michael G
AU  - Abraham MG
AD  - University of Kansas Medical Center, Kansas City, Kansas, USA.
FAU - Janardhan, Vallabh
AU  - Janardhan V
AD  - Texas Stroke Institute, Plano, Texas, USA.
FAU - Shaltoni, Hashem
AU  - Shaltoni H
AD  - University of Texas Health Science Center, Houston, Texas, USA.
FAU - Novakovic, Robin
AU  - Novakovic R
AD  - Department of Radiology, Neurology, UT Southwestern Medical Center, Dallas, Texas, 
      USA.
FAU - Yoo, Albert J
AU  - Yoo AJ
AD  - Division of Diagnostic and Interventional Neuroradiology, Department of Radiology, 
      Massachusetts General Hospital, Boston, Massachusetts, USA.
FAU - Abou-Chebl, Alex
AU  - Abou-Chebl A
AD  - Baptist Health System, Louisville, Kentucky, USA.
FAU - Chen, Peng Roc
AU  - Chen PR
AD  - Department of Neurosurgery, University of Texas, Houston, Texas, USA.
FAU - Britz, Gavin W
AU  - Britz GW
AD  - Department of Neurosurgery, Methodist Neurological Institute, Houston, Texas, USA.
FAU - Kaushal, Ritesh
AU  - Kaushal R
AD  - Saint Louis University, St. Louis, Missouri, USA.
FAU - Nanda, Ashish
AU  - Nanda A
AD  - University of Missouri, Columbia, Missouri, USA.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
LA  - eng
PT  - Journal Article
DEP - 20171011
TA  - Interv Neurol
JT  - Interventional neurology
JID - 101606828
PMC - PMC5881148
OTO - NOTNLM
OT  - Aspiration technique
OT  - Stent retriever
OT  - Stroke
OT  - Thrombectomy
EDAT- 2018/04/10 06:00
MHDA- 2018/04/10 06:01
CRDT- 2018/04/10 06:00
PHST- 2018/04/10 06:00 [entrez]
PHST- 2018/04/10 06:00 [pubmed]
PHST- 2018/04/10 06:01 [medline]
AID - ine-0007-0026 [pii]
AID - 10.1159/000480353 [doi]
PST - ppublish
SO  - Interv Neurol. 2018 Feb;7(1-2):26-35. doi: 10.1159/000480353. Epub 2017 Oct 11.

PMID- 30847500
OWN - NLM
STAT- Publisher
LR  - 20191120
IS  - 1869-1447 (Electronic)
IS  - 1869-1439 (Linking)
DP  - 2019 Mar 7
TI  - Angiographic Patterns and Outcomes Achieved by Proximal Balloon Occlusion in 
      Symptomatic Carotid Artery Stenosis Stenting.
LID - 10.1007/s00062-019-00770-8 [doi]
AB  - BACKGROUND AND PURPOSE: The best embolic protection strategy has not yet been 
      established for carotid artery stenting (CAS). This article reports a new simplified 
      approach using a balloon guide catheter inspired by stroke therapy, in patients 
      harboring a symptomatic ICA atherosclerotic stenosis or web. In addition, the three 
      angiographic patterns and clinical outcomes associated with this technique, called 
      the simple flow blockage (SFB) technique are described. MATERIAL AND METHODS: This 
      was a retrospective study with data extraction from a monocentric prospective 
      clinical registry of consecutive patients admitted for symptomatic ICA stenosis or 
      web. The primary study outcome (composite endpoint) was the rate of occurrence of 
      death, symptomatic stroke or acute coronary syndrome within 30 days of the 
      intervention. RESULTS: In this study 75 symptomatic patients with >50% carotid 
      artery atherosclerotic stenosis or web were included. All procedures were 
      successfully performed. The composite endpoint occurred in 3 patients (4.0%, 95% 
      confidence interval, CI, 0.0-11.3): 1 had symptomatic ischemic stroke, 1 had 
      reperfusion syndrome with symptomatic intracranial hemorrhage and 1 had acute 
      coronary syndrome. After proximal balloon inflation three angiographic patterns were 
      observed: complete contrast column stagnation in the ICA (38.7%), retrograde washout 
      of the ICA from the intracranial circulation towards the external carotid artery 
      (35.5%) and antegrade washout of contrast medium towards the intracranial 
      circulation (25.8%). The median procedure length was 40 min. New asymptomatic 
      ischemic lesions were observed in 22.5% on DWI-MRI. CONCLUSION: The SFB technique 
      enables fast and safe procedures in CAS. A favorable angiographic pattern after 
      proximal balloon inflation was observed in 74.2% of cases.
FAU - Dargazanli, Cyril
AU  - Dargazanli C
AUID- ORCID: 0000-0003-1891-9157
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France. 
      c.dargazanli@gmail.com.
AD  - Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Department of 
      Neuroscience, Institute of Functional Genomics, UMR 5203 CNRS - U 1191 INSERM, 
      University of Montpellier, Montpellier, France. c.dargazanli@gmail.com.
FAU - Mahmoudi, Mehdi
AU  - Mahmoudi M
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Cappucci, Matteo
AU  - Cappucci M
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Collemiche, François-Louis
AU  - Collemiche FL
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Labreuche, Julien
AU  - Labreuche J
AD  - EA 2694-Santé Publique: Épidémiologie et Qualité des Soins, Univ. Lille, CHU Lille, 
      59000, Lille, France.
FAU - Habza, Othmane
AU  - Habza O
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Gascou, Grégory
AU  - Gascou G
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Lefèvre, Pierre-Henri
AU  - Lefèvre PH
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Eker, Omer
AU  - Eker O
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Mourand, Isabelle
AU  - Mourand I
AD  - Neurology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Gaillard, Nicolas
AU  - Gaillard N
AD  - Neurology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Charif, Mahmoud
AU  - Charif M
AD  - Neurology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Derraz, Imad
AU  - Derraz I
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Arquizan, Caroline
AU  - Arquizan C
AD  - Neurology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
FAU - Costalat, Vincent
AU  - Costalat V
AD  - Neuroradiology Department, Gui de Chauliac Hospital, Montpellier University Hospital 
      Center, 81 avenue Augustin Fliche, 34295, Montpellier, France.
AD  - Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Department of 
      Neuroscience, Institute of Functional Genomics, UMR 5203 CNRS - U 1191 INSERM, 
      University of Montpellier, Montpellier, France.
LA  - eng
PT  - Journal Article
DEP - 20190307
PL  - Germany
TA  - Clin Neuroradiol
JT  - Clinical neuroradiology
JID - 101526693
OTO - NOTNLM
OT  - Atherosclerosis
OT  - Endarterectomy
OT  - Endovascular
OT  - Intimal Dysplasia
OT  - Stroke
EDAT- 2019/03/09 06:00
MHDA- 2019/03/09 06:00
CRDT- 2019/03/09 06:00
PHST- 2018/11/02 00:00 [received]
PHST- 2019/02/15 00:00 [accepted]
PHST- 2019/03/09 06:00 [entrez]
PHST- 2019/03/09 06:00 [pubmed]
PHST- 2019/03/09 06:00 [medline]
AID - 10.1007/s00062-019-00770-8 [pii]
AID - 10.1007/s00062-019-00770-8 [doi]
PST - aheadofprint
SO  - Clin Neuroradiol. 2019 Mar 7. doi: 10.1007/s00062-019-00770-8.

PMID- 29858398
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20190311
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 11
IP  - 1
DP  - 2019 Jan
TI  - Longer stent retrievers enhance thrombectomy performance in acute stroke.
PG  - 6-8
LID - 10.1136/neurintsurg-2018-013918 [doi]
AB  - BACKGROUND: Longer stent retrievers have recently become available and have 
      theoretical advantages over their shorter counterparts. We aim to evaluate whether 
      stent retriever length impacts reperfusion rates in stroke thrombectomy. METHODS: 
      This was a retrospective analysis of a prospectively collected thrombectomy database 
      in which equal diameter (4 mm) stent retrievers were used as the first-line strategy 
      for intracranial internal carotid or middle cerebral artery M1 or M2 occlusions 
      along with a balloon guide catheter from June 2011 to March 2017. The population was 
      dichotomized into long (Trevo 4×30 mm/Solitaire 4×40 mm) or short (Trevo 
      4×20 mm/Solitaire 4×20 mm) retrievers. The primary outcome was first-pass modified 
      Thrombolysis in Cerebral Infarction (mTICI) 2b/3 reperfusion. RESULTS: Of 1126 
      thrombectomies performed within the study period, 420 were included. Age, gender, 
      National Institutes of Health Stroke Scale, ASPECTS, IV tissue plasminogen activator 
      use, stroke etiology, occlusion site, time from last-known-normal to puncture, 
      distribution of Trevo and Solitaire, and the use of newer generation local 
      thromboaspiration devices were comparable between the long and short retrievers. The 
      short retriever group had more frequent hypertension, dyslipidemia, and atrial 
      fibrillation. First-pass mTICI 2b/3 reperfusion was more common in the long 
      retriever group (62% vs 50%; P=0.01). Parenchymal hematomas type 2, subarachnoid 
      hemorrhage, 90-day modified Rankin Scale score 0-2, and mortality were comparable. 
      Multivariable analysis indicated that long retriever (OR 2.2; 95% CI 1.3 to 3.6; 
      P=0.001), radiopaque device (OR 2.1; 95% CI 1.2 to 3.4; P=0.003), and adjuvant local 
      aspiration (OR 2.4; 95% CI 1.3 to 4.3; P=0.003) were independently associated with 
      first-pass reperfusion. CONCLUSIONS: The use of longer stent retrievers is an 
      independent predictor of first-pass mTICI 2b/3 reperfusion. First-pass reperfusion 
      was also associated with the use of radiopaque devices and adjuvant local 
      aspiration.
CI  - © Article author(s) (or their employer(s) unless otherwise stated in the text of the 
      article) 2019. All rights reserved. No commercial use is permitted unless otherwise 
      expressly granted.
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Al-Bayati, Alhamza R
AU  - Al-Bayati AR
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Grossberg, Jonathan A
AU  - Grossberg JA
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Bouslama, Mehdi
AU  - Bouslama M
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Barreira, Clara
AU  - Barreira C
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Bianchi, Nicolas
AU  - Bianchi N
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Frankel, Michael R
AU  - Frankel MR
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Emory University/Marcus Stroke and Neuroscience Center-Grady Memorial Hospital, 
      Atlanta, Florida, USA.
LA  - eng
PT  - Journal Article
DEP - 20180601
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
RN  - EC 3.4.21.68 (PLAT protein, human)
RN  - EC 3.4.21.68 (Tissue Plasminogen Activator)
SB  - IM
MH  - Aged
MH  - Brain Ischemia/diagnosis/surgery
MH  - Cerebral Infarction/diagnosis/*surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Reperfusion/*instrumentation/methods
MH  - Retrospective Studies
MH  - *Stents
MH  - Stroke/diagnosis/*surgery
MH  - Thrombectomy/*instrumentation/methods
MH  - Tissue Plasminogen Activator/administration & dosage
MH  - Treatment Outcome
OTO - NOTNLM
OT  - stroke
OT  - thrombectomy
COIS- Competing interests: RGN: Stryker-Neurovacular (Trevo-2 and DAWN/Trial PI), Covidien 
      (SWIFT and SWIFT-PRIME/Steering- Committee, STAR Trial/Core-Lab), Penumbra (3-D 
      Separator Trial/Executive-Committee).
EDAT- 2018/06/03 06:00
MHDA- 2019/03/12 06:00
CRDT- 2018/06/03 06:00
PHST- 2018/03/08 00:00 [received]
PHST- 2018/04/19 00:00 [revised]
PHST- 2018/04/26 00:00 [accepted]
PHST- 2018/06/03 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
PHST- 2018/06/03 06:00 [entrez]
AID - neurintsurg-2018-013918 [pii]
AID - 10.1136/neurintsurg-2018-013918 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2019 Jan;11(1):6-8. doi: 10.1136/neurintsurg-2018-013918. Epub 
      2018 Jun 1.

PMID- 31197024
OWN - NLM
STAT- MEDLINE
DCOM- 20200317
LR  - 20200317
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 12
IP  - 1
DP  - 2020 Jan
TI  - ANCD thrombectomy device: in vitro evaluation.
PG  - 77-81
LID - 10.1136/neurintsurg-2019-014856 [doi]
AB  - INTRODUCTION: Endovascular treatment of stroke, although highly effective, may fail 
      to reach complete recanalization in around 20% of cases. The Advanced Thrombectomy 
      System (ANCD) is a novel stroke thrombectomy device designed to reduce clot 
      fragmentation and facilitate retrieval by inducing local flow arrest and allowing 
      distal aspiration in combination with a stent retriever. We aimed to assess the 
      preclinical efficacy of ANCD. METHODS: Soft red blood cell (RBC)-rich (n=20/group) 
      and sticky fibrin-rich (n=30/group) clots were used to create middle cerebral artery 
      (MCA) occlusions in two vascular phantoms. Three different treatment strategies were 
      tested: (1) balloon guide catheter + Solitaire (BGC+SR); (2) distal access catheter 
      + SR (DAC+SR); and (3) ANCD+SR, until complete recanalization was achieved or to a 
      maximum of three passes. The recanalization rate was determined after each pass. 
      RESULTS: After one pass, ANCD+SR resulted in an increased recanalization rate (94%) 
      for all clots together compared with BGC+SR (66%; p<0.01) or DAC+SR (80%; p=0.04). 
      After the final pass the recanalization rate increased in all three groups but 
      remained higher with ANCD+SR (100%) than with BGC+SR (74%; p<0.01) or DAC+SR (90%; 
      p=0.02). The mean number of passes was lower with ANCD+SR (1.06) than with BGC+SR 
      (1.46) or DAC+SR (1.25) (p=0.01). A logistic regression model adjusted for treatment 
      arm, clot type, and model used showed that both RBC-rich clots (OR 8.1, 95% CI 1.6 
      to 13.5) and ANCD+SR (OR 3.9, 95% CI 1.01 to 15.8) were independent predictors of 
      first-pass recanalization. CONCLUSION: In in vitro three-dimensional models 
      replicating MCA-M1 occlusion, ANCD+SR showed significantly better recanalization 
      rates in fewer passes than other commonly used combinations of devices.
CI  - © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Sanchez, Sonia
AU  - Sanchez S
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Cortiñas, Ignacio
AU  - Cortiñas I
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Villanova, Helena
AU  - Villanova H
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Rios, Anna
AU  - Rios A
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Galve, Iñaki
AU  - Galve I
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Andersson, Tommy
AU  - Andersson T
AD  - Departments of Radiology and Neurology, AZ Groeninge, Kortrijk, Belgium.
AD  - Departments of Neuroradiology and Clinical Neuroscience, Karolinska University 
      Hospital, Karolinska Institutet, Stockholm, Sweden.
FAU - Nogueira, Raul
AU  - Nogueira R
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
FAU - Jovin, Tudor
AU  - Jovin T
AD  - Department of Neurology, UPMC, Pittsburgh, Pennsylvania, USA.
FAU - Ribo, Marc
AU  - Ribo M
AD  - Stroke Unit. Neurology, Hospital Vall d'Hebron, Barcelona, Spain.
AD  - Universitat Autònoma de Barcelona, Barcelona, Spain.
LA  - eng
PT  - Journal Article
DEP - 20190613
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
RN  - 9001-31-4 (Fibrin)
SB  - IM
MH  - Fibrin
MH  - Humans
MH  - Infarction, Middle Cerebral Artery/surgery
MH  - *Models, Cardiovascular
MH  - *Stents
MH  - Stroke/surgery
MH  - Surgical Instruments
MH  - Thrombectomy/*instrumentation/*methods
MH  - Thrombosis/surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - device
OT  - stroke
OT  - thrombectomy
COIS- Competing interests: SS, IC, HV, AR, and IG are employees of Anaconda Biomed. MR and 
      TJ are shareholders in Anaconda Biomed. TA and RN are clinical consultants for 
      Anaconda Biomed. RN is a consultant/advisory board member for Stryker Neurovascular 
      and Covidien. Stryker Neurovascular (Trevo-2 trial principal investigator–modest; 
      DAWN trial principal investigator–no compensation; TREVO registry steering 
      committee–no compensation), Medtronic (SWIFT trial steering committee–modest; 
      SWIFT-Prime trial steering committee–no compensation; STAR Trial Angiographic Core 
      Lab–significant), Penumbra (3D Separator trial executive committee–no compensation), 
      Neuravi (ARISE-2 steering committee–no compensation), Genentech (physician advisory 
      board–modest), Allm Inc (physician advisory board–no compensation). TA is a 
      consultant for Ablynx, Amnis Therapeutics, Anaconda,Cerenovus/Neuravi, Medtronic, 
      Rapid Medical. MR is a consultant for Cerenovus, Medtronic, Stryker, Apta Targets 
      and Vesalio. TJ is a consultant for Stryker Neurovascular (PI DAWN-unpaid); 
      Ownership Interest: Anaconda; Advisory Board/Investor: FreeOx Biotech; Advisory 
      Board/Investor: Route92; Advisory Board/Investor: Blockade Medical, Consultant; 
      Honoraria: Cerenovus.
EDAT- 2019/06/15 06:00
MHDA- 2020/03/18 06:00
CRDT- 2019/06/15 06:00
PHST- 2019/04/01 00:00 [received]
PHST- 2019/05/14 00:00 [revised]
PHST- 2019/05/14 00:00 [accepted]
PHST- 2019/06/15 06:00 [pubmed]
PHST- 2020/03/18 06:00 [medline]
PHST- 2019/06/15 06:00 [entrez]
AID - neurintsurg-2019-014856 [pii]
AID - 10.1136/neurintsurg-2019-014856 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2020 Jan;12(1):77-81. doi: 10.1136/neurintsurg-2019-014856. Epub 
      2019 Jun 13.

PMID- 29904305
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 0899-8280 (Print)
IS  - 1525-3252 (Electronic)
IS  - 0899-8280 (Linking)
VI  - 31
IP  - 3
DP  - 2018 Jul
TI  - Successful reperfusion of bilateral middle cerebral artery embolic occlusions using 
      stent retriever thrombectomy.
PG  - 339-341
LID - 10.1080/08998280.2018.1447182 [doi]
AB  - A 40-year-old woman presented to our stroke center for a left middle cerebral artery 
      embolic occlusion. This was successfully treated with mechanical thrombectomy using 
      a stent retriever and balloon guide catheter aspiration. The patient was discharged 
      home in good condition on clopidogrel but returned 2 months later with a 
      contralateral right middle cerebral artery embolic occlusion. This was also 
      successfully treated, this time with a stent retriever and local aspiration (Sol-Arc 
      technique). She was once again discharged in good condition but with warfarin and an 
      implanted loop recorder. This case demonstrates the feasibility of short-term 
      bilateral mechanical thrombectomy for embolic middle cerebral artery occlusions.
FAU - Miller, Austin
AU  - Miller A
AD  - Department of Radiology, Baylor University Medical Center, Dallas, Texas.
FAU - Onofrio, Anthony
AU  - Onofrio A
AD  - Department of Radiology, Baylor University Medical Center, Dallas, Texas.
FAU - Graybeal, Dion
AU  - Graybeal D
AD  - Division of Neurology, Department of Internal Medicine, Baylor University Medical 
      Center, Dallas, Texas.
FAU - Mir, Osman
AU  - Mir O
AD  - Division of Neurology, Department of Internal Medicine, Baylor University Medical 
      Center, Dallas, Texas.
FAU - Linebarger, Megan B
AU  - Linebarger MB
AD  - Department of Radiology, Baylor University Medical Center, Dallas, Texas.
FAU - Layton, Kennith F
AU  - Layton KF
AD  - Department of Radiology, Baylor University Medical Center, Dallas, Texas.
LA  - eng
PT  - Case Reports
DEP - 20180425
TA  - Proc (Bayl Univ Med Cent)
JT  - Proceedings (Baylor University. Medical Center)
JID - 9302033
PMC - PMC5997098
OTO - NOTNLM
OT  - Embolus
OT  - ischemia
OT  - stent retriever
OT  - stroke
OT  - thrombectomy
EDAT- 2018/06/16 06:00
MHDA- 2018/06/16 06:01
CRDT- 2018/06/16 06:00
PHST- 2017/10/16 00:00 [received]
PHST- 2018/01/15 00:00 [revised]
PHST- 2018/01/18 00:00 [accepted]
PHST- 2018/06/16 06:00 [entrez]
PHST- 2018/06/16 06:00 [pubmed]
PHST- 2018/06/16 06:01 [medline]
AID - 1447182 [pii]
AID - 10.1080/08998280.2018.1447182 [doi]
PST - epublish
SO  - Proc (Bayl Univ Med Cent). 2018 Apr 25;31(3):339-341. doi: 
      10.1080/08998280.2018.1447182. eCollection 2018 Jul.

PMID- 26919972
OWN - NLM
STAT- MEDLINE
DCOM- 20170324
LR  - 20181202
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 9
IP  - 2
DP  - 2017 Feb
TI  - An in vitro evaluation of distal emboli following Lazarus Cover-assisted stent 
      retriever thrombectomy.
PG  - 183-187
LID - 10.1136/neurintsurg-2015-012256 [doi]
AB  - BACKGROUND: Formation of clot fragments during mechanical thrombectomy for acute 
      ischemic stroke can occlude the distal vasculature, which may reduce the rate of 
      good clinical outcome. OBJECTIVE: To examine the hypothesis that distal embolization 
      can be reduced using stent retriever thrombectomy in combination with Lazarus Cover 
      technology. METHODS: Hard, fragment-prone clots were used to create middle cerebral 
      artery occlusions in a vascular phantom. Three different treatment strategies using 
      Solitaire FR included: group 1-proximal flow control with an 8F balloon guide 
      catheter (BGC), group 2-thrombectomy through a 6F conventional guide catheter (CGC), 
      and group 3-a similar thrombectomy procedure to group 2 but including the Lazarus 
      Cover device. The primary endpoint was distal emboli quantified by the number and 
      size of the clot debris. RESULTS: The Cover-assisted stent retriever thrombectomy 
      significantly reduced the generation of clot fragments >200 μm as compared with 
      thrombectomy with a CGC, and was similar to the BGC group. Particle size 
      distribution <200 μm was similar across the groups. All groups were associated with 
      high rates of recanalization, with only one failed recanalization with partial clot 
      retention after three passes in one experiment of stent retriever thrombectomy 
      through a CGC. Use of the adjunctive Cover device did not prolong the procedure as 
      compared with control groups. CONCLUSIONS: For a fragment-prone clot, Solitaire 
      thrombectomy in conjunction with the Cover device may lower the risk of distal 
      embolization and is comparable to BGC-protected embolectomy.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/.
FAU - Chueh, Ju-Yu
AU  - Chueh JY
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts, Worcester, Massachusetts, USA.
FAU - Puri, Ajit S
AU  - Puri AS
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts, Worcester, Massachusetts, USA.
FAU - Gounis, Matthew J
AU  - Gounis MJ
AD  - Department of Radiology, New England Center for Stroke Research, University of 
      Massachusetts, Worcester, Massachusetts, USA.
LA  - eng
PT  - Journal Article
DEP - 20160226
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Brain Ischemia/surgery
MH  - Cerebral Angiography
MH  - Device Removal/*adverse effects/methods
MH  - Embolization, Therapeutic/*methods
MH  - Infarction, Middle Cerebral Artery/surgery
MH  - Intracranial Embolism/diagnostic imaging/*etiology
MH  - Particle Size
MH  - *Stents
MH  - Stroke/surgery
MH  - Thrombectomy/*adverse effects/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - *Device
OT  - *Stroke
OT  - *Thrombectomy
EDAT- 2016/02/28 06:00
MHDA- 2017/03/25 06:00
CRDT- 2016/02/28 06:00
PHST- 2015/12/30 00:00 [received]
PHST- 2016/01/28 00:00 [revised]
PHST- 2016/01/30 00:00 [accepted]
PHST- 2016/02/28 06:00 [pubmed]
PHST- 2017/03/25 06:00 [medline]
PHST- 2016/02/28 06:00 [entrez]
AID - neurintsurg-2015-012256 [pii]
AID - 10.1136/neurintsurg-2015-012256 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2017 Feb;9(2):183-187. doi: 10.1136/neurintsurg-2015-012256. 
      Epub 2016 Feb 26.

PMID- 16908572
OWN - NLM
STAT- MEDLINE
DCOM- 20060929
LR  - 20121115
IS  - 0195-6108 (Print)
IS  - 0195-6108 (Linking)
VI  - 27
IP  - 7
DP  - 2006 Aug
TI  - Clot removal therapy by aspiration and extraction for acute embolic carotid 
      occlusion.
PG  - 1521-7
AB  - BACKGROUND AND PURPOSE: The purpose of our retrospective study was to investigate 
      the feasibility, safety, and efficacy of clot removal therapy by aspiration and 
      extraction for patients with acute stroke with embolic internal carotid artery (ICA) 
      occlusion. METHODS: Of 814 consecutive patients with acute ischemic stroke admitted 
      to our institution from March 2003 to April 2005, clot removal therapy was performed 
      for 14. Inclusion criteria were patients (1) presenting within 6 hours of onset of 
      cardioembolic stroke, (2) with serious neurologic symptoms defined by a National 
      Institutes of Health Stroke Scale (NIHSS) score of at least 11, (3) without 
      extensive high signal intensity on diffusion-weighted MR images but with decreased 
      ipsilateral hemispheric cerebral blood flow on perfusion-weighted images 
      (perfusion/diffusion mismatch), and (4) with total ICA occlusion on angiograms. We 
      removed clots by aspiration and extraction with a microsnare through either a 
      guiding or balloon guide catheter. Radiographic results, 7-day NIHSS, 3-month 
      modified Rankin Scale, and procedure-related complications were evaluated. RESULTS: 
      Of 10 patients treated with the balloon guide catheter to temporarily interrupt 
      proximal flow, 7 obtained complete or partial recanalization. The 4 patients treated 
      with the guiding catheter had no recanalization. Of the 7 patients with 
      recanalization, 6 had favorable 7-day neurologic and 3-month functional outcome; all 
      showed anatomic crossflow via the anterior communicating artery. A procedure-related 
      complication, distal embolization into the ipsilateral anterior cerebral artery, 
      occurred in 1 patient. CONCLUSION: Balloon guide catheter-assisted clot removal 
      therapy for embolic ICA occlusion may provide a high recanalization rate and good 
      clinical outcome in patients with anatomic crossflow.
FAU - Imai, K
AU  - Imai K
AD  - Department of Stroke Treatment, Shonan Kamakura General Hospital, 1201-1 Yamazaki 
      Kamakura, Kanagawa 247-8533, Japan.
FAU - Mori, T
AU  - Mori T
FAU - Izumoto, H
AU  - Izumoto H
FAU - Takabatake, N
AU  - Takabatake N
FAU - Kunieda, T
AU  - Kunieda T
FAU - Shimizu, H
AU  - Shimizu H
FAU - Watanabe, M
AU  - Watanabe M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - AJNR Am J Neuroradiol
JT  - AJNR. American journal of neuroradiology
JID - 8003708
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Volume/physiology
MH  - Brain Ischemia/therapy
MH  - Carotid Artery Thrombosis/*therapy
MH  - Carotid Artery, Internal/*pathology
MH  - Catheterization/instrumentation
MH  - Cerebral Angiography
MH  - Cerebrovascular Circulation/physiology
MH  - Diffusion Magnetic Resonance Imaging
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Intracranial Embolism/*therapy
MH  - Male
MH  - *Micromanipulation/instrumentation
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Stroke/therapy
MH  - *Suction/instrumentation
MH  - Tomography, X-Ray Computed
MH  - Treatment Outcome
EDAT- 2006/08/16 09:00
MHDA- 2006/09/30 09:00
CRDT- 2006/08/16 09:00
PHST- 2006/08/16 09:00 [pubmed]
PHST- 2006/09/30 09:00 [medline]
PHST- 2006/08/16 09:00 [entrez]
AID - 27/7/1521 [pii]
PST - ppublish
SO  - AJNR Am J Neuroradiol. 2006 Aug;27(7):1521-7.

PMID- 32015181
OWN - NLM
STAT- Publisher
LR  - 20200213
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
DP  - 2020 Feb 3
TI  - Balloon anchoring technique for t hrombectomy in hostile craniocervical arterial 
      anatomy.
LID - neurintsurg-2019-015347 [pii]
LID - 10.1136/neurintsurg-2019-015347 [doi]
AB  - BACKGROUND: Craniocervical catheter access in large vessel occlusion acute ischemic 
      strokes can be challenging in cases of unfavorable aortic arch/cervical vascular 
      anatomy, leading to lower recanalization rates, increased procedural time and worse 
      clinical outcomes. We aim to demonstrate the feasibility of the balloon-anchoring 
      technique (BAT) that can be attempted before switching to alternative access sites. 
      METHODS: Retrospective review of prospectively collected information on 11 patients 
      in which two variants of the BAT (proximal anchoring: balloon guide catheter (BGC) 
      is inflated to provide support for distal access; distal anchoring: compliant 
      balloon is inflated in an intracranial artery to allow advancement of the support 
      system) were utilized to facilitate craniocervical access due to failure of 
      conventional maneuvers. RESULTS: Ten patients had anterior and one patient had 
      posterior circulation large vessel occlusions. Mean age was 81 years and 81% were 
      females. Type 3 arches were found in 82% and a 9 French balloon guide catheter was 
      used in 82%. Proximal anchoring with BGC was used in four cases while distal 
      anchoring was used in seven patients to allow access to the target vessel, avoiding 
      the need to puncture alternative access sites. Successful reperfusion (modified 
      treatment in cerebral ischemia 2b-3) was achieved in all cases and no complications 
      were observed. CONCLUSION: BAT is safe and feasible. It can be considered as a 
      rescue maneuver in order to avoid switching to a different access during 
      thrombectomy in individuals with unfavorable aortic arch/craniocervical anatomy.
CI  - © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Sharashidze, Vera
AU  - Sharashidze V
AD  - Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
AD  - Marcus Stroke & Neuroscience Center - Grady Memorial Hospital, Emory University 
      School of Medicine, Atlanta, Georgia, USA.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
AD  - Marcus Stroke & Neuroscience Center - Grady Memorial Hospital, Emory University 
      School of Medicine, Atlanta, Georgia, USA.
FAU - Al-Bayati, Alhamza R
AU  - Al-Bayati AR
AD  - Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
AD  - Marcus Stroke & Neuroscience Center - Grady Memorial Hospital, Emory University 
      School of Medicine, Atlanta, Georgia, USA.
FAU - Grossberg, Jonathan A
AU  - Grossberg JA
AD  - Neurosurgery and Radiology, Emory University School of Medicine, Atlanta, Georgia, 
      USA.
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Neurology, Emory University School of Medicine, Atlanta, Georgia, USA 
      diogo.haussen@emory.edu.
AD  - Marcus Stroke & Neuroscience Center - Grady Memorial Hospital, Emory University 
      School of Medicine, Atlanta, Georgia, USA.
LA  - eng
PT  - Journal Article
DEP - 20200203
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
OTO - NOTNLM
OT  - CT angiography
OT  - CT perfusion
OT  - artery
OT  - balloon
OT  - catheter
COIS- Competing interests: VS: None. AA: None. JG: None. DCH:Consultant for Stryker and 
      Vesalio; Viz-Ai stock options. RGN: Principal Investigator, Stryker Neurovascular 
      (DAWN trial[no compensation],Trevo-2 trial), Cerenovus/Neuravi (ENDOLOW trial, no 
      compensation); consultant to Stryker Neurovascular; steering committee member, 
      Stryker Neurovascular (no compensation), Medtronic (SWIFT trial, SWIFT Prime trial 
      [no compensation]), Cerenovus/Neuravi (ARISE-2 trial, no compensation); angiographic 
      core lab, Medtronic (STAR trial); executive committee member, Penumbra (no 
      compensation); physician advisory board, Cerenovus/Neuravi, Phenox, Anaconda, 
      Genentech, Biogen, Prolong Pharmaceuticals, Allm Inc. (no compensation), Viz-AI; 
      stock options,Viz-AI.
EDAT- 2020/02/06 06:00
MHDA- 2020/02/06 06:00
CRDT- 2020/02/05 06:00
PHST- 2019/09/29 00:00 [received]
PHST- 2019/12/27 00:00 [revised]
PHST- 2020/01/04 00:00 [accepted]
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2020/02/06 06:00 [medline]
PHST- 2020/02/05 06:00 [entrez]
AID - neurintsurg-2019-015347 [pii]
AID - 10.1136/neurintsurg-2019-015347 [doi]
PST - aheadofprint
SO  - J Neurointerv Surg. 2020 Feb 3:neurintsurg-2019-015347. doi: 
      10.1136/neurintsurg-2019-015347.

PMID- 30760625
OWN - NLM
STAT- MEDLINE
DCOM- 20191126
LR  - 20191126
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 11
IP  - 9
DP  - 2019 Sep
TI  - Institutional and provider variations for mechanical thrombectomy in the treatment 
      of acute ischemic stroke: a survey analysis.
PG  - 884-890
LID - 10.1136/neurintsurg-2018-014614 [doi]
AB  - INTRODUCTION: Stent retriever combined with aspiration, or the 'Solumbra technique', 
      has recently emerged as one of the popular methods of mechanical thrombectomy (MT). 
      However, the variations in understanding and implementation of the Solumbra 
      technique have not been reported. METHODS: An 18 part anonymous survey questionnaire 
      was designed to extract information regarding technical variations of MT with a 
      focus on the Solumbra technique. The survey link was posted on the Society of 
      Neurointerventional Surgery (SNIS) website in 'SNIS connect'. RESULTS: 80 responses 
      were obtained over 4 weeks that were included in the final analysis. Direct 
      aspiration without a balloon guide catheter (BGC) was the most favored technique 
      among respondents (41.12%) followed by the Solumbra technique without a BGC (32.4%). 
      Among those using the Solumbra technique, 77.6% reported that they wait between 2 
      and 5 min to allow clot engagement, 55.2% always remove the microcatheter before 
      aspiration, and 69.1% commence aspiration through the intermediate catheter only 
      when retrieving the stent retriever. Operators who infrequently used or did not use 
      BGCs reported a higher incidence of >80% Thrombolysis in Cerebral Infarction 2b/3 
      annual recanalization rates (OR 8.85, 95% CI 2.03 to 38.55, P=0.004) compared with 
      those who consistently used BGCs. CONCLUSION: Our study documents the variations in 
      MT techniques, and more specifically, attempts to quantify variations in the 
      Solumbra technique. The impact of these variations on recanalization rates and 
      eventually patient outcomes are unclear, especially given the self-reported outcomes 
      contained in this study.
CI  - © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Mehta, Tapan
AU  - Mehta T
AD  - Department of Neurology, Neurosurgery and Radiology, University of Minnesota, 
      Minneapolis, MN, USA.
FAU - Male, Shailesh
AU  - Male S
AUID- ORCID: 0000-0002-3217-7869
AD  - Department of Neurology, Neurosurgery and Radiology, University of Minnesota, 
      Minneapolis, MN, USA.
FAU - Quinn, Coridon
AU  - Quinn C
AD  - Department of Neurology, Neurosurgery and Radiology, University of Minnesota, 
      Minneapolis, MN, USA.
FAU - Kallmes, David F
AU  - Kallmes DF
AD  - Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
FAU - Siddiqui, Adnan H
AU  - Siddiqui AH
AUID- ORCID: 0000-0002-9519-0059
AD  - Department of Neurosurgery and Radiology, University at Buffalo, Buffalo, New York, 
      USA.
FAU - Turk, Aquilla
AU  - Turk A
AD  - Department of Neurosurgery and Radiology, Medical University of South Carolina, 
      Charleston, South Carolina, USA.
FAU - Grande, Andrew Walker
AU  - Grande AW
AD  - Department of Neurology, Neurosurgery and Radiology, University of Minnesota, 
      Minneapolis, MN, USA.
FAU - Tummala, Ramachandra Prasad
AU  - Tummala RP
AD  - Department of Neurology, Neurosurgery and Radiology, University of Minnesota, 
      Minneapolis, MN, USA.
FAU - Jagadeesan, Bharathi Dasan
AU  - Jagadeesan BD
AD  - Department of Neurology, Neurosurgery and Radiology, University of Minnesota, 
      Minneapolis, MN, USA.
LA  - eng
PT  - Journal Article
DEP - 20190213
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
MH  - Brain Ischemia/epidemiology/*surgery
MH  - Female
MH  - Health Personnel/standards
MH  - Humans
MH  - Male
MH  - Stents
MH  - Stroke/epidemiology/*surgery
MH  - *Surveys and Questionnaires
MH  - Thrombectomy/*methods/standards
MH  - Treatment Outcome
OTO - NOTNLM
OT  - stroke
OT  - thrombectomy
COIS- Competing interests: None declared.
EDAT- 2019/02/15 06:00
MHDA- 2019/11/27 06:00
CRDT- 2019/02/15 06:00
PHST- 2018/12/05 00:00 [received]
PHST- 2019/01/04 00:00 [revised]
PHST- 2019/01/09 00:00 [accepted]
PHST- 2019/02/15 06:00 [pubmed]
PHST- 2019/11/27 06:00 [medline]
PHST- 2019/02/15 06:00 [entrez]
AID - neurintsurg-2018-014614 [pii]
AID - 10.1136/neurintsurg-2018-014614 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2019 Sep;11(9):884-890. doi: 10.1136/neurintsurg-2018-014614. 
      Epub 2019 Feb 13.

PMID- 29652229
OWN - NLM
STAT- Publisher
LR  - 20191120
IS  - 1933-0693 (Electronic)
IS  - 0022-3085 (Linking)
DP  - 2018 Apr 1
TI  - A useful diagnostic method to reduce the in-hospital time delay for mechanical 
      thrombectomy: volume perfusion computed tomography with added vessel reconstruction.
PG  - 1-8
LID - 2017.10.JNS171971 [pii]
LID - 10.3171/2017.10.JNS171971 [doi]
AB  - OBJECTIVEVolume perfusion CT (VPCT) with added CT angiography (CTA)-like 
      reconstruction from VPCT source data (VPCTA) can reveal multiple intracranial 
      parameters. The authors examined the usefulness of VPCTA in terms of reducing the 
      in-hospital time delay for mechanical thrombectomy.METHODSA total of 180 patients 
      who underwent mechanical thrombectomy at the authors' institution between January 
      2014 and March 2017 were divided into 2 groups: a CTA-based thrombectomy decision 
      group (group 1: CTA) and a VPCTA-based decision group (group 2: VPCTA). Multiple 
      time interval categories (from symptom onset to groin puncture, from hospital 
      arrival to groin puncture, procedure time, from symptom onset to reperfusion, and 
      from hospital arrival to reperfusion) were reviewed. All patients underwent clinical 
      assessment with the National Institutes of Health Stroke Scale score and the 
      modified Rankin Scale, and radiological results were evaluated by the Thrombolysis 
      in Cerebral Infarction score.RESULTSIn all of the time interval categories except 
      for procedure time, the VPCTA group showed a significantly shorter in-hospital time 
      delay during the prethrombectomy period than did the CTA group. The 3-month modified 
      Rankin Scale score was significantly lower in the VPCTA group (2.8) compared with 
      the CTA group (3.5) (p = 0.003). However, there were no statistically significant 
      differences between the 2 groups in the other clinical and radiological 
      outcomes.CONCLUSIONSCompared with CTA, VPCTA significantly reduced the in-hospital 
      time delay during the prethrombectomy period.
FAU - Yi, Ho Jun
AU  - Yi HJ
FAU - Sung, Jae Hoon
AU  - Sung JH
FAU - Lee, Dong Hoon
AU  - Lee DH
FAU - Yang, Seung Ho
AU  - Yang SH
FAU - Hong, Jae Taek
AU  - Hong JT
LA  - eng
PT  - Journal Article
DEP - 20180401
PL  - United States
TA  - J Neurosurg
JT  - Journal of neurosurgery
JID - 0253357
OTO - NOTNLM
OT  - BGC = balloon guide catheter
OT  - CBF = cerebral blood flow
OT  - CBV = cerebral blood volume
OT  - CTA = CT angiography
OT  - ER = emergency room
OT  - ICA = internal carotid artery
OT  - MCA = middle cerebral artery
OT  - MTT = mean transit time
OT  - NIHSS = National Institutes of Health Stroke Scale
OT  - TIA = transient ischemic attack
OT  - TICI = Thrombolysis in Cerebral Infarction
OT  - TTP = time to peak
OT  - VPCT = volume perfusion CT
OT  - VPCTA = VPCT with CTA-like reconstruction from VPCT source data
OT  - VRT = volume-rendering technique
OT  - angiography
OT  - computed tomography
OT  - mRS = modified Rankin Scale
OT  - perfusion
OT  - stroke
OT  - tPA = tissue plasminogen activator
OT  - thrombectomy
OT  - vascular disorders
EDAT- 2018/04/14 06:00
MHDA- 2018/04/14 06:00
CRDT- 2018/04/14 06:00
PHST- 2017/08/09 00:00 [received]
PHST- 2017/10/16 00:00 [accepted]
PHST- 2018/04/14 06:00 [pubmed]
PHST- 2018/04/14 06:00 [medline]
PHST- 2018/04/14 06:00 [entrez]
AID - 2017.10.JNS171971 [pii]
AID - 10.3171/2017.10.JNS171971 [doi]
PST - aheadofprint
SO  - J Neurosurg. 2018 Apr 1:1-8. doi: 10.3171/2017.10.JNS171971.

PMID- 31563889
OWN - NLM
STAT- In-Process
LR  - 20200416
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 12
IP  - 5
DP  - 2020 May
TI  - Effects of first pass recanalization on outcomes of contact aspiration thrombectomy.
PG  - 466-470
LID - 10.1136/neurintsurg-2019-015221 [doi]
AB  - BACKGROUND: First pass recanalization (FPR, defined as achieving a modified 
      Thrombolysis in Cerebral Ischemia (mTICI) grade 2c/3 with a single pass of a 
      thrombectomy device) effect has not yet been evaluated in contact aspiration 
      thrombectomy (CAT). We evaluated FPR effect on clinical outcomes and FPR predictors 
      in CAT. METHODS: All consecutive patients who underwent frontline CAT for anterior 
      circulation large vessel occlusion with recanalization (mTICI 2b-3) were identified 
      from registries at six stroke centers. The patients were dichotomized into FPR and 
      non-FPR groups. Clinical features and outcomes were compared between the groups. 
      Multivariate analyses were performed to determine whether FPR was independently 
      associated with clinical outcomes and to identify predictors of FPR. RESULTS: Of the 
      429 patients who underwent frontline CAT, recanalization was successful in 344 
      patients (80.2%; mean age 68.7±11.0 years; M:F ratio 179:165). The FPR group had a 
      higher rate of good outcome (modified Rankin Scale score 0-2) than the non-FPR 
      group. Furthermore, the good outcome rate was higher in the FPR group than in 
      patients who achieved mTICI 2c/3 with multiple passes or rescue treatment. FPR (OR 
      2.587; 95% CI 1.237 to 5.413) remained independently associated with good outcomes, 
      in addition to age, baseline National Institute Health Stroke Scale, and coronary 
      artery disease. The use of a balloon guide catheter (OR 3.071; 95% CI 1.699 to 
      5.550) was the only predictor of FPR. CONCLUSIONS: Patients in the FPR group had 
      better clinical outcomes than the non-FPR group in CAT. FPR was independently 
      associated with a good outcome. The use of a balloon guide catheter was the only 
      predictor of FPR.
CI  - © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Kang, Dong-Hun
AU  - Kang DH
AD  - Department of Neurosurgery, School of Medicine, Kyungpook National University, 
      Daegu, Republic of Korea.
AD  - Department of Radiology, School of Medicine, Kyungpook National University, Daegu, 
      Republic of Korea.
FAU - Kim, Byung Moon
AU  - Kim BM
AUID- ORCID: 0000-0001-8593-6841
AD  - Department of Radiology, Yonsei University College of Medicine, Severance Hospital, 
      Seoul, Republic of Korea.
FAU - Heo, Ji Hoe
AU  - Heo JH
AD  - Department of Neurology, Yonsei University College of Medicine, Severance Hospital, 
      Seoul, Republic of Korea.
FAU - Nam, Hyo Suk
AU  - Nam HS
AD  - Department of Neurology, Yonsei University College of Medicine, Severance Hospital, 
      Seoul, Republic of Korea.
FAU - Kim, Young Dae
AU  - Kim YD
AD  - Department of Neurology, Yonsei University College of Medicine, Severance Hospital, 
      Seoul, Republic of Korea.
FAU - Hwang, Yang Ha
AU  - Hwang YH
AD  - Department of Neurology, School of Medicine, Kyungpook National University, Daegu, 
      Republic of Korea.
FAU - Kim, Yong-Won
AU  - Kim YW
AUID- ORCID: 0000-0003-0674-0352
AD  - Department of Neurology, School of Medicine, Kyungpook National University, Daegu, 
      Republic of Korea.
FAU - Kim, Dong Joon
AU  - Kim DJ
AUID- ORCID: 0000-0002-7035-087X
AD  - Department of Radiology, Yonsei University College of Medicine, Severance Hospital, 
      Seoul, Republic of Korea.
FAU - Kim, Joon Whi
AU  - Kim JW
AD  - Department of Radiology, Yonsei University College of Medicine, Severance Hospital, 
      Seoul, Republic of Korea.
FAU - Baek, Jang-Hyun
AU  - Baek JH
AD  - Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of 
      Medicine, Suwon, Republic of Korea.
FAU - Kim, Yong-Sun
AU  - Kim YS
AD  - Department of Radiology, School of Medicine, Kyungpook National University, Daegu, 
      Republic of Korea.
LA  - eng
PT  - Journal Article
DEP - 20190928
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
OTO - NOTNLM
OT  - acute stroke
OT  - aspiration
OT  - first pass
OT  - outcome
OT  - thrombectomy
COIS- Competing interests: None declared.
EDAT- 2019/09/30 06:00
MHDA- 2019/09/30 06:00
CRDT- 2019/09/30 06:00
PHST- 2019/06/24 00:00 [received]
PHST- 2019/08/27 00:00 [revised]
PHST- 2019/09/06 00:00 [accepted]
PHST- 2019/09/30 06:00 [pubmed]
PHST- 2019/09/30 06:00 [medline]
PHST- 2019/09/30 06:00 [entrez]
AID - neurintsurg-2019-015221 [pii]
AID - 10.1136/neurintsurg-2019-015221 [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2020 May;12(5):466-470. doi: 10.1136/neurintsurg-2019-015221. 
      Epub 2019 Sep 28.

PMID- 24668201
OWN - NLM
STAT- MEDLINE
DCOM- 20140703
LR  - 20161122
IS  - 1524-4628 (Electronic)
IS  - 0039-2499 (Linking)
VI  - 45
IP  - 5
DP  - 2014 May
TI  - North American SOLITAIRE Stent-Retriever Acute Stroke Registry: choice of anesthesia 
      and outcomes.
PG  - 1396-401
LID - 10.1161/STROKEAHA.113.003698 [doi]
AB  - BACKGROUND AND PURPOSE: Previous work that predated the availability of the safer 
      stent-retriever devices has suggested that general anesthesia (GA) may have a 
      negative impact on outcomes in patients with acute ischemic stroke undergoing 
      endovascular therapy. METHODS: We reviewed demographic, clinical, procedural (GA 
      versus local anesthesia [LA], etc), and site-adjudicated angiographic and clinical 
      outcomes data from consecutive patients treated with the Solitaire FR device in the 
      investigator-initiated North American SOLITAIRE Stent-Retriever Acute Stroke (NASA) 
      Registry. The primary outcomes were 90-day modified Rankin Scale, mortality, and 
      symptomatic intracranial hemorrhage. RESULTS: A total of 281 patients from 18 
      centers were enrolled. GA was used in 69.8% (196/281) of patients. Baseline 
      demographic and procedural factors were comparable between the LA and GA groups, 
      except the former demonstrated longer time-to-groin puncture (395.4±254 versus 
      337.4±208 min; P=0.04), lower National Institutes of Health Stroke Scale (NIHSS; 
      16.2±5.8 versus 18.8±6.9; P=0.002), lower balloon-guide catheter usage (22.4% versus 
      49.2%; P=0.0001), and longer fluoroscopy times (39.5±33 versus 28±22.8 min; 
      P=0.008). Recanalization (thrombolysis in cerebral infarction ≥2b; 72.94% versus 
      73.6%; P=0.9) and rate of symptomatic intracranial hemorrhage (7.1% versus 11.2%; 
      P=0.4) were similar but modified Rankin Scale ≤2 was achieved in more LA patients, 
      52.6% versus 35.6% (odds ratio, 1.4 [1.1-1.8]; P=0.01). In multivariate analysis, 
      hypertension, NIHSS, unsuccessful revascularization, and GA use (odds ratio, 3.3 
      [1.6-7.1]; P=0.001) were associated with death. When only anterior circulation and 
      elective GA patients were included, there was a persistent difference in good 
      outcomes in favor of LA patients (50.7% versus 35.5%; odds ratio, 1.3 [1.01-1.6]; 
      P=0.04). CONCLUSIONS: The NASA Registry has demonstrated that clinical outcomes and 
      survival are significantly better in patients treated with LA, without increased 
      symptomatic intracranial hemorrhage risk. Future trials should prospectively 
      evaluate the effect of GA on outcomes.
FAU - Abou-Chebl, Alex
AU  - Abou-Chebl A
AD  - From the Texas Stroke Institute, Plano, TX (A.A.-C., V.J.); Departments of 
      Neurology, Neurosurgery, and Radiology, Medical College of Wisconsin/Froedtert 
      Hospital, Atlanta, GA (O.O.Z., A.C.C., M.A.I.); Wellstar Neurosurgery Kennestone 
      Hospital, Atlanta, GA (R.G.); Department of Neurology, Emory University School of 
      Medicine, Atlanta, GA (C.-H.J.S. R.G.N.); Saint Luke's Kansas City, Kansas City, MO 
      (C.O.M., W.E.H.); Department of Neurology, Delray Medical Center, Delray Beach, FL 
      (N.M.-K.); California Pacific Medical Center, San Francisco, CA (J.D.E.); Division 
      of Interventional Neuroradiology, Baptist Cardiac and Vascular Institute, Miami, FL 
      (I.L., G.D.); Alexian Brothers Medical Center, Elk Grove Village, IL (T.W.M., 
      F.A.M.); Oregon Health and Science University, Portland, OR (H.B.); Department of 
      Neurology, Wayne State University School of Medicine, Detroit, MI (A.X.); Department 
      of Radiology, West Virginia University Hospital, Morgantown, WV (A.T.R.); 
      Departments of Neurology, Neurosurgery, Radiology, Vanderbilt University Medical 
      Center, Nashville, TN (M.T.F.); Provena Saint Joseph Medical Center, Joliet, IL 
      (A.B.); Departments of Neurology, Neurosurgery, Radiology, Boston Medical Center, 
      Boston, MA (T.N.N.); Desert Regional Medical Center, Palm Springs, CA (M.T.); 
      University of Kansas Medical Center, Kansas City, KS (M.G.A.); University of Texas 
      Health Science Center, Houston, TX (H.S.); Departments of Radiology, Neurology, UT 
      Southwestern Medical Center, Dallas, TX (R.N.); Department of Radiology, Division of 
      Diagnostic and Interventional Neuroradiology, Massachusetts General Hospital, 
      Boston, MA (A.J.Y.); University of Texas, Houston, TX (P.R.C.); Department of 
      Neurosurgery, Houston Methodist, Methodist Neurological Institute, Houston, TX 
      (G.W.B.); Saint Louis University, St. Louis, MO (R.K.); and University of Missouri, 
      Columbia, MO (A.N.).
FAU - Zaidat, Ossama O
AU  - Zaidat OO
FAU - Castonguay, Alicia C
AU  - Castonguay AC
FAU - Gupta, Rishi
AU  - Gupta R
FAU - Sun, Chung-Huan J
AU  - Sun CH
FAU - Martin, Coleman O
AU  - Martin CO
FAU - Holloway, William E
AU  - Holloway WE
FAU - Mueller-Kronast, Nils
AU  - Mueller-Kronast N
FAU - English, Joey D
AU  - English JD
FAU - Linfante, Italo
AU  - Linfante I
FAU - Dabus, Guilherme
AU  - Dabus G
FAU - Malisch, Timothy W
AU  - Malisch TW
FAU - Marden, Franklin A
AU  - Marden FA
FAU - Bozorgchami, Hormozd
AU  - Bozorgchami H
FAU - Xavier, Andrew
AU  - Xavier A
FAU - Rai, Ansaar T
AU  - Rai AT
FAU - Froehler, Micahel T
AU  - Froehler MT
FAU - Badruddin, Aamir
AU  - Badruddin A
FAU - Nguyen, Thanh N
AU  - Nguyen TN
FAU - Taqi, Muhammad
AU  - Taqi M
FAU - Abraham, Michael G
AU  - Abraham MG
FAU - Janardhan, Vallabh
AU  - Janardhan V
FAU - Shaltoni, Hashem
AU  - Shaltoni H
FAU - Novakovic, Roberta
AU  - Novakovic R
FAU - Yoo, Albert J
AU  - Yoo AJ
FAU - Chen, Peng R
AU  - Chen PR
FAU - Britz, Gavin W
AU  - Britz GW
FAU - Kaushal, Ritesh
AU  - Kaushal R
FAU - Nanda, Ashish
AU  - Nanda A
FAU - Issa, Mohammad A
AU  - Issa MA
FAU - Nogueira, Raul G
AU  - Nogueira RG
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
DEP - 20140325
PL  - United States
TA  - Stroke
JT  - Stroke
JID - 0235266
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Anesthesia, General/adverse effects/mortality/*statistics & numerical data
MH  - Anesthesia, Local/adverse effects/mortality/*statistics & numerical data
MH  - Brain Ischemia/mortality/*therapy
MH  - Endovascular Procedures/adverse effects/mortality/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - North America
MH  - Registries/*statistics & numerical data
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Stents/*statistics & numerical data
MH  - Stroke/mortality/*therapy
MH  - Treatment Outcome
OTO - NOTNLM
OT  - anesthesia
OT  - stroke
EDAT- 2014/03/29 06:00
MHDA- 2014/07/06 06:00
CRDT- 2014/03/27 06:00
PHST- 2014/03/27 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2014/07/06 06:00 [medline]
AID - STROKEAHA.113.003698 [pii]
AID - 10.1161/STROKEAHA.113.003698 [doi]
PST - ppublish
SO  - Stroke. 2014 May;45(5):1396-401. doi: 10.1161/STROKEAHA.113.003698. Epub 2014 Mar 
      25.

PMID- 28843759
OWN - NLM
STAT- MEDLINE
DCOM- 20171225
LR  - 20171225
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 107
DP  - 2017 Nov
TI  - Hybrid Technique for the Treatment of Refractory Vertebrobasilar Insufficiencies.
PG  - 1051.e13-1051.e17
LID - S1878-8750(17)31382-7 [pii]
LID - 10.1016/j.wneu.2017.08.081 [doi]
AB  - BACKGROUND: Tortuous or occluded vertebral arteries (VAs) can make the endovascular 
      treatment of vertebrobasilar insufficiency impractical. Bypass surgery is an option, 
      but a craniotomy of the posterior fossa is complicated when physiologic vessels must 
      be abandoned. We report 3 cases of refractory vertebrobasilar insufficiency with 
      different presentations requiring problematic approaches in which the patients were 
      treated by different hybrid strategies. CASE DESCRIPTION: Patient 1 had severe 
      stenosis of right VA ostium with right V1 segment tortuosity and was treated by 
      right VA ostium transposition during which the proximal subclavian artery was 
      blocked by a balloon guide catheter. Patient 2 had severe stenosis of the basilar 
      artery and bilateral VA tortuosity. The V1 segment was exposed and cut open so that 
      an available approach for endovascular procedures was created. Patient 3 had 
      bilateral VA occlusion. After exposure of the left V1 segment, recanalization of the 
      left VA was performed by an interventional radiologist and surgeon working together. 
      All patients had improved hemodynamics and symptoms alleviated without major 
      complications. CONCLUSIONS: For refractory vertebrobasilar insufficiencies, hybrid 
      operations that combine surgical manipulation of the V1 segment and endovascular 
      techniques can be safe and effective.
CI  - Copyright © 2017. Published by Elsevier Inc.
FAU - Lu, Xia
AU  - Lu X
AD  - Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, 
      China.
FAU - Ma, Yan
AU  - Ma Y
AD  - Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, 
      China.
FAU - Yang, Bin
AU  - Yang B
AD  - Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, 
      China.
FAU - Gao, Peng
AU  - Gao P
AD  - Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, 
      China.
FAU - Wang, Yabing
AU  - Wang Y
AD  - Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, 
      China.
FAU - Jiao, Liqun
AU  - Jiao L
AD  - Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, 
      China. Electronic address: liqunjiao@sina.cn.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170823
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Aged
MH  - Arterial Occlusive Diseases/diagnostic imaging/surgery
MH  - Endovascular Procedures/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Treatment Outcome
MH  - Vertebrobasilar Insufficiency/*diagnostic imaging/*surgery
OTO - NOTNLM
OT  - Hybrid operation
OT  - Vertebral artery occlusion
OT  - Vertebral artery recanalization
OT  - Vertebral artery transposition
OT  - Vertebrobasilar insufficiency
EDAT- 2017/08/28 06:00
MHDA- 2017/12/26 06:00
CRDT- 2017/08/28 06:00
PHST- 2017/05/29 00:00 [received]
PHST- 2017/08/10 00:00 [revised]
PHST- 2017/08/12 00:00 [accepted]
PHST- 2017/08/28 06:00 [pubmed]
PHST- 2017/12/26 06:00 [medline]
PHST- 2017/08/28 06:00 [entrez]
AID - S1878-8750(17)31382-7 [pii]
AID - 10.1016/j.wneu.2017.08.081 [doi]
PST - ppublish
SO  - World Neurosurg. 2017 Nov;107:1051.e13-1051.e17. doi: 10.1016/j.wneu.2017.08.081. 
      Epub 2017 Aug 23.

PMID- 17245008
OWN - NLM
STAT- MEDLINE
DCOM- 20070316
LR  - 20190606
IS  - 0470-8105 (Print)
IS  - 0470-8105 (Linking)
VI  - 47
IP  - 1
DP  - 2007 Jan
TI  - Experimental model evaluation of filter trapping after embolectomy using the Merci 
      system: supplemental technique for Merci retrieval procedure.
PG  - 11-7
AB  - Examination of embolectomy using the Merci Retrieval System using experimental 
      stroke models demonstrated that aspiration is not adequate to remove larger clots. 
      The effectiveness of filter trapping was examined using the same models. A silicone 
      model of the carotid artery system with model blood clot was incorporated in a 
      laboratory pulsatile flow system. Embolectomy was performed using the Merci 
      Retrieval System. Any clot not evacuated through the balloon guide catheter was 
      trapped with a distal protection filter device developed for cervical stenting. The 
      clot could not be sucked into the guide catheter by the recommended procedures in 
      nine of 15 trials. Trapping failed in only one trial, in which the clot passed 
      through a gap between the edge of the filter orifice and the inner model lumen. A 
      clot was withdrawn to the catheter tip trapped across the edge of the orifice frame 
      in one trial, and a very large clot was trapped across the filter orifice in two 
      trials. Even clots made by the same method showed variation in properties, 
      especially hardness, which may affect the effectiveness of aspiration. The 
      aspiration procedure recommended for the Merci Retrieval System did not remove the 
      large clots formed by embolectomy. The trapping procedure using a filter device 
      without an orifice frame was effective to solve this problem.
FAU - Suzuki, Yasuhiro
AU  - Suzuki Y
AD  - Department of Radiology, Section of Interventional Neuroradiology, University of 
      Iowa Hospitals and Clinics, Iowa City, IA, USA. CQX05344@nifty.com
FAU - Fujitsuka, Mitsuyuki
AU  - Fujitsuka M
FAU - Chaloupka, John C
AU  - Chaloupka JC
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Neurol Med Chir (Tokyo)
JT  - Neurologia medico-chirurgica
JID - 0400775
SB  - IM
MH  - Embolectomy/*instrumentation/methods
MH  - Equipment Design
MH  - Filtration/instrumentation
MH  - Humans
MH  - Intracranial Embolism/*surgery
MH  - Models, Cardiovascular
EDAT- 2007/01/25 09:00
MHDA- 2007/03/17 09:00
CRDT- 2007/01/25 09:00
PHST- 2007/01/25 09:00 [pubmed]
PHST- 2007/03/17 09:00 [medline]
PHST- 2007/01/25 09:00 [entrez]
AID - JST.JSTAGE/nmc/47.11 [pii]
AID - 10.2176/nmc.47.11 [doi]
PST - ppublish
SO  - Neurol Med Chir (Tokyo). 2007 Jan;47(1):11-7. doi: 10.2176/nmc.47.11.

PMID- 21479799
OWN - NLM
STAT- MEDLINE
DCOM- 20120810
LR  - 20161125
IS  - 0942-0940 (Electronic)
IS  - 0001-6268 (Linking)
VI  - 153
IP  - 8
DP  - 2011 Aug
TI  - A retrieval thrombectomy technique with the Solitaire stent in a large cerebral 
      artery occlusion.
PG  - 1625-31
LID - 10.1007/s00701-011-0999-0 [doi]
AB  - BACKGROUND: To describe preliminary experiences and the procedural details of 
      retrieval thrombectomy using a self-expanding and fully retrievable Solitaire stent 
      (ev 3 Inc., CA, USA) in acute ischemic stroke (AIS) patients with large artery 
      occlusions. METHODS: Eight patients with AIS were treated by mechanical thrombectomy 
      using a self-expanding, fully retrievable stent (Solitaire, ev 3 Inc., CA, USA). The 
      stent was deployed to cover the whole intra-arterial clot and then it was slowly 
      retrieved while occluding the internal cerebral artery (ICA) with a balloon guiding 
      catheter. Additionally, continuous negative pressure was applied through the balloon 
      guiding catheter with a specially designed gun device. Occlusion sites were M1 in 
      six cases including one combined supraclinoid ICA occlusion and the other combined 
      M2 occlusion, M2 in 1 case and one basilar artery top. RESULTS: Complete 
      recanalization was achieved in all patients. Procedure time was 45 min or less in 
      seven cases and 70 min in one case. Distal emboli occurred in one case in which the 
      balloon guide catheter was not used. Only in this case was intraarterial 
      fibrinolytics infusion necessary. There was no post-operative intracranial 
      hemorrhage. CONCLUSIONS: In our experience, retrieval thrombectomy with the 
      Solitaire stent was a simple and effective method for reopening large cerebral 
      arteries in AIS patients.
FAU - Park, Hyun
AU  - Park H
AD  - Department of Neurosurgery, Jeju National University School of Medicine, Jeju 
      National University Hospital, Ara-1-dong, Jeju-Si, Jeju Self-Governing Province 
      690-716, Korea.
FAU - Hwang, Gyo Jun
AU  - Hwang GJ
FAU - Jin, Sung-Chul
AU  - Jin SC
FAU - Jung, Cheol-Kyu
AU  - Jung CK
FAU - Bang, Jae Seung
AU  - Bang JS
FAU - Han, Moon Ku
AU  - Han MK
FAU - Bae, Hee Jun
AU  - Bae HJ
FAU - Choe, Ghee Young
AU  - Choe GY
FAU - Oh, Chang Wan
AU  - Oh CW
FAU - Kwon, O-Ki
AU  - Kwon OK
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20110410
PL  - Austria
TA  - Acta Neurochir (Wien)
JT  - Acta neurochirurgica
JID - 0151000
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Vessel Prosthesis Implantation/instrumentation/methods
MH  - Catheterization/instrumentation/methods
MH  - Cerebral Revascularization/instrumentation/methods
MH  - Female
MH  - Humans
MH  - Intracranial Thrombosis/diagnostic imaging/pathology/*therapy
MH  - Male
MH  - Radiography
MH  - Stents/*standards
MH  - Thrombectomy/*instrumentation/*methods
MH  - Treatment Outcome
EDAT- 2011/04/12 06:00
MHDA- 2012/08/11 06:00
CRDT- 2011/04/12 06:00
PHST- 2011/01/11 00:00 [received]
PHST- 2011/03/14 00:00 [accepted]
PHST- 2011/04/12 06:00 [entrez]
PHST- 2011/04/12 06:00 [pubmed]
PHST- 2012/08/11 06:00 [medline]
AID - 10.1007/s00701-011-0999-0 [doi]
PST - ppublish
SO  - Acta Neurochir (Wien). 2011 Aug;153(8):1625-31. doi: 10.1007/s00701-011-0999-0. Epub 
      2011 Apr 10.

PMID- 31295596
OWN - NLM
STAT- MEDLINE
DCOM- 20200123
LR  - 20200123
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 130
DP  - 2019 Oct
TI  - Transarterial Embolization of Dural Arteriovenous Fistula in Superior Sagittal Sinus 
      Under Bilateral External Carotid Artery Flow Control: Technical Note.
PG  - 227-230
LID - S1878-8750(19)31908-4 [pii]
LID - 10.1016/j.wneu.2019.07.012 [doi]
AB  - BACKGROUND: Transarterial embolization (TAE) using liquid embolic material is a 
      standard treatment for non-sinus-type dural arteriovenous fistula (DAVF). However, 
      to reach embolic material over a shunt point for complete obliteration of DAVF is 
      often difficult. We present a technical case report of the efficacy of bilateral 
      external carotid artery (ECA) flow control for the TAE of superior sagittal sinus 
      DAVF. CASE DESCRIPTION: A 64-year-old man presented with dizziness and left 
      hemiparesis. Computed tomography imaging showed right parietal subcortical 
      hemorrhage, and cerebral angiography revealed a DAVF in the superior sagittal sinus 
      fed by bilateral occipital artery, bilateral superficial temporal artery and 
      bilateral middle meningeal artery (MMA), with cortical venous reflux and without 
      connection to the superior sagittal sinus. We therefore planned TAE using glue via 
      MMA under bilateral ECA flow control. A 7-Fr balloon guide catheter was positioned 
      in the bilateral ECA origins, and a microcatheter was introduced distal to the MMA. 
      Heated 20% n-butyl-2-cyanoacrylate was slowly injected via the left MMA under 
      bilateral ECA origin flow control. The n-butyl-2-cyanoacrylate reached the shunt 
      point and obliterated the shunt in a single session. The patient was discharged 
      without neurological symptoms. CONCLUSIONS: Bilateral ECA flow control using balloon 
      guide catheter is safe and effective for a DAVF in the superior sagittal sinus with 
      multiple and tortuous scalp feeders.
CI  - Copyright © 2019 Elsevier Inc. All rights reserved.
FAU - Kotsugi, Masashi
AU  - Kotsugi M
AD  - Department of Neurosurgery, Nara Medical University, Nara, Japan.
FAU - Nakagawa, Ichiro
AU  - Nakagawa I
AD  - Department of Neurosurgery, Nara Medical University, Nara, Japan. Electronic 
      address: nakagawa@naramed-u.ac.jp.
FAU - Takamura, Yoshiaki
AU  - Takamura Y
AD  - Department of Neurosurgery, Nara Medical University, Nara, Japan.
FAU - Wada, Takeshi
AU  - Wada T
AD  - Department of Radiology, Nara Medical University, Nara, Japan.
FAU - Kichikawa, Kimihiko
AU  - Kichikawa K
AD  - Department of Radiology, Nara Medical University, Nara, Japan.
FAU - Nakase, Hiroyuki
AU  - Nakase H
AD  - Department of Neurosurgery, Nara Medical University, Nara, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20190708
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Carotid Artery, External/*surgery
MH  - Central Nervous System Vascular Malformations/diagnosis/*surgery
MH  - Cerebral Angiography/methods
MH  - Dura Mater/blood supply/*surgery
MH  - Embolization, Therapeutic/methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Superior Sagittal Sinus/*surgery
MH  - *Vascular Surgical Procedures
OTO - NOTNLM
OT  - Balloon
OT  - Fistula
OT  - Liquid embolic material
EDAT- 2019/07/12 06:00
MHDA- 2020/01/24 06:00
CRDT- 2019/07/12 06:00
PHST- 2019/06/03 00:00 [received]
PHST- 2019/06/29 00:00 [revised]
PHST- 2019/07/01 00:00 [accepted]
PHST- 2019/07/12 06:00 [pubmed]
PHST- 2020/01/24 06:00 [medline]
PHST- 2019/07/12 06:00 [entrez]
AID - S1878-8750(19)31908-4 [pii]
AID - 10.1016/j.wneu.2019.07.012 [doi]
PST - ppublish
SO  - World Neurosurg. 2019 Oct;130:227-230. doi: 10.1016/j.wneu.2019.07.012. Epub 2019 
      Jul 8.

PMID- 23124642
OWN - NLM
STAT- MEDLINE
DCOM- 20131104
LR  - 20161125
IS  - 1936-959X (Electronic)
IS  - 0195-6108 (Linking)
VI  - 34
IP  - 5
DP  - 2013 May
TI  - Treatment of acute vertebrobasilar occlusion using thrombectomy with stent 
      retrievers: initial experience with 18 patients.
PG  - 1044-8
LID - 10.3174/ajnr.A3329 [doi]
AB  - BACKGROUND AND PURPOSE: Acute vertebrobasilar occlusion is an ominous disease with 
      few proved effective treatments. Experience with stent retrievers is scarce and 
      limited to combined therapies (stent retrievers associated with previous intravenous 
      fibrinolysis, intra-arterial thrombolysis, or other mechanical devices). We present 
      our experience with 18 patients treated with direct thrombectomy by using stent 
      retrievers. MATERIALS AND METHODS: Eighteen patients with vertebrobasilar occlusion 
      were treated with direct thrombectomy by using stent retrievers at our hospital. The 
      mean age was 67.5 years. Clinical presentation was sudden deterioration in 
      consciousness level in 61.2% and progressive or fluctuating brain stem symptoms in 
      38.8%. Stroke subtype (TOAST) was atherothrombotic (33.3%), undetermined (33.3%), 
      cardioembolic (27.7%), and of unusual etiology (5.5%). RESULTS: The occlusion site 
      was the vertebral artery in 1 case, proximal basilar artery in 4, middle basilar 
      artery in 6, distal basilar artery in 5, and unilateral posterior cerebral artery in 
      2 cases. SRs included the Solitaire AB in 8 cases, Solitaire FR in 5 cases, and 
      Trevo Pro in 5 cases. An 8F Merci balloon guide catheter was used in 15 patients, 
      and a Neuron 6F, in 3 patients. Post-clot retrieval definitive intracranial stents 
      were used in 5 patients (27.7%). Postprocedural TICI ≥ 2b was achieved in 17 
      patients (94.4%). Clinically, 72.2% of patients experienced an improved NIHSS score 
      at discharge, 22.2% died, and in 5.5% the NIHSS scores did not change. The mRS score 
      at 3 months was 0-2 in 9 patients (50%) and 3-5 in 5 patients (27.7%). CONCLUSIONS: 
      Thrombectomy with stent retrievers is feasible in the treatment of vertebrobasilar 
      occlusion. These initial results must be confirmed by further prospective studies 
      with a larger number of cases.
FAU - Espinosa de Rueda, M
AU  - Espinosa de Rueda M
AD  - Department of Interventional Neuroradiology, Hospital Universitario Virgen de la 
      Arrixaca, Murcia, Spain. mm.espinosa@gmail.com
FAU - Parrilla, G
AU  - Parrilla G
FAU - Zamarro, J
AU  - Zamarro J
FAU - García-Villalba, B
AU  - García-Villalba B
FAU - Hernández, F
AU  - Hernández F
FAU - Moreno, A
AU  - Moreno A
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20121101
PL  - United States
TA  - AJNR Am J Neuroradiol
JT  - AJNR. American journal of neuroradiology
JID - 8003708
SB  - IM
MH  - Acute Disease
MH  - Aged
MH  - *Blood Vessel Prosthesis
MH  - Device Removal/*instrumentation
MH  - Female
MH  - Humans
MH  - Male
MH  - Pilot Projects
MH  - *Stents
MH  - Thrombectomy/*instrumentation
MH  - Tomography, X-Ray Computed
MH  - Treatment Outcome
MH  - Vertebrobasilar Insufficiency/*diagnostic imaging/*surgery
EDAT- 2012/11/06 06:00
MHDA- 2013/11/05 06:00
CRDT- 2012/11/06 06:00
PHST- 2012/11/06 06:00 [entrez]
PHST- 2012/11/06 06:00 [pubmed]
PHST- 2013/11/05 06:00 [medline]
AID - ajnr.A3329 [pii]
AID - 10.3174/ajnr.A3329 [doi]
PST - ppublish
SO  - AJNR Am J Neuroradiol. 2013 May;34(5):1044-8. doi: 10.3174/ajnr.A3329. Epub 2012 Nov 
      1.

PMID- 32419724
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200522
IS  - 0739-9529 (Print)
IS  - 1098-8963 (Electronic)
IS  - 0739-9529 (Linking)
VI  - 37
IP  - 2
DP  - 2020 Jun
TI  - Evolution of Stroke Thrombectomy Techniques to Optimize First-Pass Complete 
      Reperfusion.
PG  - 119-131
LID - 10.1055/s-0040-1709153 [doi]
AB  - Since 2015, endovascular therapy (EVT) has become the standard of care for acute 
      ischemic stroke (AIS) due to large vessel occlusion. It is a safe and highly 
      effective treatment, and its number needed to treat of 2.6 is one of the highest 
      throughout medicine. The ultimate goal when performing EVT is to maximize chances of 
      good outcome through achievement of fast first-pass complete reperfusion, as 
      incomplete and delayed reperfusion increases complication rates and negatively 
      affects outcome. Since EVT has been established as standard of care, new devices 
      have been developed and treatment techniques have been refined. This review provides 
      a brief overview about the rationale for and history of EVT, followed by a detailed 
      step-by-step description of how to perform EVT using the BADDASS (BAlloon guide with 
      large bore Distal access catheter with Dual Aspiration with Stent-retriever as 
      Standard approach), a combined technique, which is in our opinion the safest and 
      most effective way to achieve fast first-pass complete reperfusion. We also discuss 
      treatment strategies for patients with simultaneous high-grade carotid 
      stenosis/pseudoocclusion/occlusion and gaining carotid access in challenging arch 
      anatomy, as these are commonly encountered situations in AIS, and conclude with an 
      outlook on new technologies and future directions of EVT.
CI  - © Thieme Medical Publishers.
FAU - Ospel, Johanna Maria
AU  - Ospel JM
AD  - Department of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University 
      Hospital of Basel, Basel, Switzerland.
AD  - Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
FAU - McTaggart, Ryan
AU  - McTaggart R
AD  - Department of Interventional Radiology, Warren Alpert Medical School of Brown 
      University, Providence, Rhode Island.
FAU - Kashani, Nima
AU  - Kashani N
AD  - Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
AD  - Department of Radiology, University of Calgary, Calgary, Canada.
FAU - Psychogios, Marios
AU  - Psychogios M
AD  - Department of Neuroradiology, Clinic of Radiology and Nuclear Medicine, University 
      Hospital of Basel, Basel, Switzerland.
FAU - Almekhlafi, Mohammed
AU  - Almekhlafi M
AD  - Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
AD  - Department of Radiology, University of Calgary, Calgary, Canada.
FAU - Goyal, Mayank
AU  - Goyal M
AD  - Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
AD  - Department of Radiology, University of Calgary, Calgary, Canada.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200514
TA  - Semin Intervent Radiol
JT  - Seminars in interventional radiology
JID - 8510974
PMC - PMC7224978
OTO - NOTNLM
OT  - aspiration
OT  - balloon guide catheter
OT  - endovascular therapy
OT  - interventional radiology
OT  - ischemic stroke
OT  - mechanical thrombectomy
OT  - reperfusion
COIS- Conflict of Interest None.
EDAT- 2020/05/19 06:00
MHDA- 2020/05/19 06:01
PMCR- 2021/06/01
CRDT- 2020/05/19 06:00
PHST- 2021/06/01 00:00 [pmc-release]
PHST- 2020/05/19 06:00 [entrez]
PHST- 2020/05/19 06:00 [pubmed]
PHST- 2020/05/19 06:01 [medline]
AID - 001188 [pii]
AID - 10.1055/s-0040-1709153 [doi]
PST - ppublish
SO  - Semin Intervent Radiol. 2020 Jun;37(2):119-131. doi: 10.1055/s-0040-1709153. Epub 
      2020 May 14.

PMID- 27076599
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20161230
IS  - 1524-4539 (Electronic)
IS  - 0009-7322 (Linking)
VI  - 133
IP  - 23
DP  - 2016 Jun 7
TI  - Analysis of Workflow and Time to Treatment on Thrombectomy Outcome in the 
      Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke 
      (ESCAPE) Randomized, Controlled Trial.
PG  - 2279-86
LID - 10.1161/CIRCULATIONAHA.115.019983 [doi]
AB  - BACKGROUND: The Endovascular Treatment for Small Core and Proximal Occlusion 
      Ischemic Stroke (ESCAPE) trial used innovative imaging and aggressive target time 
      metrics to demonstrate the benefit of endovascular treatment in patients with acute 
      ischemic stroke. We analyze the impact of time on clinical outcome and the effect of 
      patient, hospital, and health system characteristics on workflow within the trial. 
      METHODS AND RESULTS: Relationship between outcome (modified Rankin Scale) and 
      interval times was modeled by using logistic regression. Association between time 
      intervals (stroke onset to arrival in endovascular-capable hospital, to qualifying 
      computed tomography, to groin puncture, and to reperfusion) and patient, hospital, 
      and health system characteristics were modeled by using negative binomial 
      regression. Every 30-minute increase in computed tomography-to-reperfusion time 
      reduced the probability of achieving a functionally independent outcome (90-day 
      modified Rankin Scale 0-2) by 8.3% (P=0.006). Symptom onset-to-imaging time was not 
      associated with outcome (P>0.05). Onset-to-endovascular hospital arrival time was 
      42% (34 minutes) longer among patients receiving intravenous alteplase at the 
      referring hospital (drip and ship) versus direct transfer (mothership). Computed 
      tomography-to-groin puncture time was 15% (8 minutes) shorter among patients 
      presenting during work hours versus off hours, 41% (24 minutes) shorter in drip-ship 
      patients versus mothership, and 43% (22 minutes) longer when general anesthesia was 
      administered. The use of a balloon guide catheter during endovascular procedures 
      shortened puncture-to-reperfusion time by 21% (8 minutes). CONCLUSIONS: 
      Imaging-to-reperfusion time is a significant predictor of outcome in the ESCAPE 
      trial. Inefficiencies in triaging, off-hour presentation, intravenous alteplase 
      administration, use of general anesthesia, and endovascular techniques offer major 
      opportunities for improvement in workflow. CLINICAL TRIAL REGISTRATION: URL: 
      http://www.clinicaltrials.gov. Unique identifier: NCT01778335.
CI  - © 2016 American Heart Association, Inc.
FAU - Menon, Bijoy K
AU  - Menon BK
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Sajobi, Tolulope T
AU  - Sajobi TT
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Zhang, Yukun
AU  - Zhang Y
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Rempel, Jeremy L
AU  - Rempel JL
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Shuaib, Ashfaq
AU  - Shuaib A
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Thornton, John
AU  - Thornton J
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Williams, David
AU  - Williams D
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Roy, Daniel
AU  - Roy D
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Poppe, Alexandre Y
AU  - Poppe AY
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Jovin, Tudor G
AU  - Jovin TG
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Sapkota, Biggya
AU  - Sapkota B
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Baxter, Blaise W
AU  - Baxter BW
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Krings, Timo
AU  - Krings T
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Silver, Frank L
AU  - Silver FL
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Frei, Donald F
AU  - Frei DF
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Fanale, Christopher
AU  - Fanale C
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Tampieri, Donatella
AU  - Tampieri D
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Teitelbaum, Jeanne
AU  - Teitelbaum J
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Lum, Cheemun
AU  - Lum C
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Dowlatshahi, Dar
AU  - Dowlatshahi D
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Eesa, Muneer
AU  - Eesa M
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Lowerison, Mark W
AU  - Lowerison MW
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Kamal, Noreen R
AU  - Kamal NR
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Demchuk, Andrew M
AU  - Demchuk AM
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Hill, Michael D
AU  - Hill MD
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.).
FAU - Goyal, Mayank
AU  - Goyal M
AD  - From Department of Clinical Neurosciences and Radiology (B.K.M., T.T.S., M.E., 
      N.R.K., A.M.D, M.D.H., M.G.) andDepartment of Community Health Sciences (B.K.M., 
      Y.Z., A.M.D.,M.D.H., M.G.), Cumming School of Medicine, University of Calgary, 
      Canada; Departments of Radiology (J.L.R.) and Medicine (A.S.), University of 
      Alberta, Edmonton, Canada; Departments of Neuroradiology (J.T.) andGeriatric and 
      Stroke Medicine(D.W.), Beaumont Hospital and the Royal College of Surgeons in 
      Ireland, Dublin; Departments of Radiology (D.R.) and Neurosciences (A.Y.P.), 
      University of Montreal, Canada; Department of Neurology, University of Pittsburgh 
      Medical Center, PA (T.G.J.); Acute Stroke Services, University of Tennessee, 
      Chattanooga (B.S.); Department of Radiology, Erlanger Hospital, University of 
      Tennessee, Chattanooga (B.W.B.); Division of Radiology (T.K.) andDivision of 
      Neurology, Department of Medicine (F.L.S.), Toronto Western Hospital, Canada; 
      Colorado Neurological Institute, Engelwood, CO (D.F.F., C.F.); Montreal Neurological 
      Institute, Canada (D.T., J.T.); Departments of Radiology (C.L.) and Neurology 
      (D.D.), University of Ottawa, Canada; Clinical Research Unit, University of Calgary, 
      Canada (M.W.L.); and Hotchkiss Brain Institute, Calgary, Canada (B.K.M., T.T.S., 
      M.E., A.M.D., M.D.H., M.G.). mgoyal@ucalgary.ca.
LA  - eng
SI  - ClinicalTrials.gov/NCT01778335
GR  - CIHR/Canada
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20160413
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
RN  - 0 (Fibrinolytic Agents)
RN  - EC 3.4.21.68 (Tissue Plasminogen Activator)
SB  - AIM
SB  - IM
CIN - Circulation. 2016 Nov 8;134(19):e404-e405. PMID: 27821425
CIN - Circulation. 2016 Nov 8;134(19):e406-e407. PMID: 27821426
MH  - Administration, Intravenous
MH  - After-Hours Care
MH  - Anesthesia, General
MH  - Brain Ischemia/diagnostic imaging/mortality/*therapy
MH  - Cerebral Angiography/methods
MH  - Computed Tomography Angiography
MH  - Disability Evaluation
MH  - *Endovascular Procedures/adverse effects/mortality
MH  - Fibrinolytic Agents/administration & dosage
MH  - Humans
MH  - Predictive Value of Tests
MH  - Punctures
MH  - Risk Factors
MH  - Stroke/diagnostic imaging/*mortality/*therapy
MH  - *Thrombectomy/adverse effects/mortality
MH  - *Thrombolytic Therapy/adverse effects/mortality
MH  - Time Factors
MH  - *Time and Motion Studies
MH  - *Time-to-Treatment
MH  - Tissue Plasminogen Activator/administration & dosage
MH  - Treatment Outcome
MH  - Triage
MH  - *Workflow
OTO - NOTNLM
OT  - cerebrovascular disorders
OT  - emergency treatment
OT  - endovascular procedures
OT  - stroke
OT  - thrombolytic therapy
EDAT- 2016/04/15 06:00
MHDA- 2016/12/15 06:00
CRDT- 2016/04/15 06:00
PHST- 2015/10/18 00:00 [received]
PHST- 2016/04/08 00:00 [accepted]
PHST- 2016/04/15 06:00 [entrez]
PHST- 2016/04/15 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - CIRCULATIONAHA.115.019983 [pii]
AID - 10.1161/CIRCULATIONAHA.115.019983 [doi]
PST - ppublish
SO  - Circulation. 2016 Jun 7;133(23):2279-86. doi: 10.1161/CIRCULATIONAHA.115.019983. 
      Epub 2016 Apr 13.

PMID- 31900353
OWN - NLM
STAT- Publisher
LR  - 20200104
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
DP  - 2020 Jan 3
TI  - Development of an in vitro model of calcified cerebral emboli in acute ischemic 
      stroke for mechanical thrombectomy evaluation.
LID - neurintsurg-2019-015595 [pii]
LID - 10.1136/neurintsurg-2019-015595 [doi]
AB  - ​ BACKGROUND: Calcified cerebral emboli (CCEs) are a rare cause of acute ischemic 
      stroke (AIS) and are frequently associated with poor outcomes. The presence of dense 
      calcified material enables reliable identification of CCEs using non-contrast CT. 
      However, recanalization rates with the available mechanical thrombectomy (MT) 
      devices remain low. OBJECTIVE: To recreate a large vessel occlusion involving a CCE 
      using an in vitro silicone model of the intracranial vessels and to demonstrate the 
      feasability of this model to test different endovascular strategies to recanalize an 
      occlusion of the M1 segment of the middle cerebral artery (MCA).​ METHODS: An in 
      vitro model was developed to evaluate different endovascular treatment approaches 
      using contemporary devices in the M1 segment of the MCA. The in vitro model 
      consisted of a CCE analog placed in a silicone neurovascular model. Development of 
      an appropriate CCE analog was based on characterization of human calcified tissues 
      that represent likely sources of CCEs. Feasibility of the model was demonstrated in 
      a small number of MT devices using four common procedural techniques.​ RESULTS: CCE 
      analogs were developed with similar mechanical behavior to that of ex vivo calcified 
      material. The in vitro model was evaluated with various MT techniques and devices to 
      show feasibility of the model. In this limited evaluation, the most successful 
      retrieval approach was performed with a stent retriever combined with local 
      aspiration through a distal access catheter, and importantly, with flow arrest and 
      dual aspiration using a balloon guide catheter.​ CONCLUSION: Characterization of 
      calcified tissues, which are likely sources of CCEs, has shown that CCEs are 
      considerably stiffer than thrombus. This highlights the need for a different in 
      vitro AIS model for CCEs than those used for thromboemboli. Consequentially, an in 
      vitro AIS model representative of a CCE occlusion in the M1 segment of the MCA has 
      been developed.
CI  - © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Johnson, Sarah
AU  - Johnson S
AUID- ORCID: 0000-0002-2372-1236
AD  - Biomedical Engineering, National University of Ireland Galway, Galway, Ireland.
FAU - McCarthy, Ray
AU  - McCarthy R
AD  - Cerenovus, Galway Neuro Technology Centre, Galway, Ireland.
FAU - Fahy, Brian
AU  - Fahy B
AD  - Cerenovus, Galway Neuro Technology Centre, Galway, Ireland.
FAU - Mereuta, Oana Madalina
AU  - Mereuta OM
AD  - Department of Physiology, National University of Ireland Galway, Galway, Ireland.
FAU - Fitzgerald, Seán
AU  - Fitzgerald S
AUID- ORCID: 0000-0001-6634-092X
AD  - Department of Physiology, National University of Ireland Galway, Galway, Ireland.
FAU - Gaudirc, Julien
AU  - Gaudirc J
AD  - Department of Vascular Surgery, Pitié-Salpêtrière Hospital, Paris, France.
FAU - Remadi, Jean-Paul
AU  - Remadi JP
AD  - Department of Cardiac Surgery, Amiens University Hospital, Amiens, France.
FAU - Shotar, Eimad
AU  - Shotar E
AD  - Department of Neuroradiology, Pitie-Salpetriere Hospital, Paris, France.
FAU - Sourour, Nader-Antoine
AU  - Sourour NA
AD  - Department of Neuroradiology, Pitie-Salpetriere Hospital, Paris, France.
FAU - Doyle, Karen
AU  - Doyle K
AD  - Department of Physiology, National University of Ireland Galway, Galway, Ireland.
FAU - Gilvarry, Michael
AU  - Gilvarry M
AD  - Cerenovus, Galway Neuro Technology Centre, Galway, Ireland.
FAU - McGarry, Patrick
AU  - McGarry P
AD  - Biomedical Engineering, National University of Ireland Galway, Galway, Ireland.
FAU - McHugh, Peter E
AU  - McHugh PE
AD  - Biomedical Engineering, National University of Ireland Galway, Galway, Ireland.
FAU - Clarençon, Frédéric
AU  - Clarençon F
AD  - Department of Neuroradiology, Pitie-Salpetriere Hospital, Paris, France 
      fredclare5@gmail.com.
AD  - Sorbonne University, Paris, France.
LA  - eng
PT  - Journal Article
DEP - 20200103
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
OTO - NOTNLM
OT  - device
OT  - embolic
OT  - stroke
OT  - thrombectomy
COIS- Competing interests: SJ reports grants from the Irish Research Council and the NUI 
      Galway Hardiman Research Scholarship during the conduct of the study, and reports 
      financial support from Cerenovus, outside the submitted work. RM and MG report a 
      financial relationship with Cerenovus outside the submitted work.
EDAT- 2020/01/05 06:00
MHDA- 2020/01/05 06:00
CRDT- 2020/01/05 06:00
PHST- 2019/11/04 00:00 [received]
PHST- 2019/12/12 00:00 [revised]
PHST- 2019/12/15 00:00 [accepted]
PHST- 2020/01/05 06:00 [entrez]
PHST- 2020/01/05 06:00 [pubmed]
PHST- 2020/01/05 06:00 [medline]
AID - neurintsurg-2019-015595 [pii]
AID - 10.1136/neurintsurg-2019-015595 [doi]
PST - aheadofprint
SO  - J Neurointerv Surg. 2020 Jan 3:neurintsurg-2019-015595. doi: 
      10.1136/neurintsurg-2019-015595.

PMID- 32132966
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200308
IS  - 1664-2295 (Print)
IS  - 1664-2295 (Electronic)
IS  - 1664-2295 (Linking)
VI  - 11
DP  - 2020
TI  - First Pass Effect in Patients Treated With the Trevo Stent-Retriever: A TRACK 
      Registry Study Analysis.
PG  - 83
LID - 10.3389/fneur.2020.00083 [doi]
LID - 83
AB  - Background and Objective: The first pass effect (FPE; achieving complete 
      recanalization with a single thrombectomy device pass) has been shown to be 
      associated with higher rates of good clinical outcomes in patients with acute 
      ischemic stroke. Here, we investigate clinical and radiographic factors associated 
      with FPE in a large U.S. post-marketing registry (TRACK, Trevo Stent-Retriever Acute 
      Stroke). Methods: We analyzed the TRACK database (multicenter registry of 634 
      patients from 23 centers from March 2013 through August 2015), which 609 patients 
      were included in the final analysis. FPE was defined as a single pass/use of device, 
      TICI 2c/3 recanalization, and no use of rescue therapy. Analysis of individual 
      patient data from TRACK were performed to analyze clinical and radiographic 
      characteristics associated with FPE as well-compared clinical outcomes defined as 
      modified Rankin Scale (mRS) score at 30 and 90 days from hospital discharge to the 
      non-FPE group. Results: The rate of FPE in TRACK was 23% (140/609). There was no 
      association between patient demographics and FPE, including age (p = 0.36), sex (p = 
      0.50), race (p = 0.50), location of occlusion (p = 0.26), baseline NIHSS (p = 0.62), 
      or past medical history. There was no difference in the use of a balloon-guide 
      catheter or general anesthesia (49 and 57% with FPE vs. 47 and 64%, p = 0.63 and p = 
      0.14, respectively). Clinical outcomes were significantly associated with FPE; 63 
      vs. 44% in non-FPE patients achieved mRS 0-2 at 90 days (p = 0.0004). Conclusion: 
      Our study showed that achieving complete recanalization with a single thrombectomy 
      pass using the Trevo device was highly beneficial. The most common clinical factors 
      that are used to determine eligibility for endovascular therapy, such as NIHSS 
      severity, location of occlusion or patient age were not predictive of the ability to 
      achieve FPE.
CI  - Copyright © 2020 Mokin, Primiani, Castonguay, Nogueira, Haussen, English, Satti, 
      Chen, Farid, Borders, Veznedaroglu, Binning, Puri, Vora, Budzik, Dabus, Linfante, 
      Janardhan, Alshekhlee, Abraham, Edgell, Taqi, Khoury, Majjhoo, Kabbani, Froehler, 
      Finch, Ansari, Novakovic, Nguyen and Zaidat.
FAU - Mokin, Maxim
AU  - Mokin M
AD  - Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, FL, 
      United States.
FAU - Primiani, Christopher T
AU  - Primiani CT
AD  - Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, FL, 
      United States.
FAU - Castonguay, Alicia C
AU  - Castonguay AC
AD  - Department of Neurology, University of Toledo, Toledo, OH, United States.
FAU - Nogueira, Raul G
AU  - Nogueira RG
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, GA, United 
      States.
FAU - Haussen, Diogo C
AU  - Haussen DC
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, GA, United 
      States.
FAU - English, Joey D
AU  - English JD
AD  - Department of Neurology, California Pacific Medical Center, San Francisco, CA, 
      United States.
FAU - Satti, Sudhakar R
AU  - Satti SR
AD  - Department of Neurointerventional Surgery, Christiana Care Health Center, Newark, 
      DE, United States.
FAU - Chen, Jennifer
AU  - Chen J
AD  - Department of Radiology, Sidney Kimmel Medical College, Philadelphia, PA, United 
      States.
FAU - Farid, Hamed
AU  - Farid H
AD  - Department of Neurointerventional Radiology, St. Jude Medical Center, Fullerton, CA, 
      United States.
FAU - Borders, Candace
AU  - Borders C
AD  - Department of Neurosurgery, Irvine School of Medicine, University of California, 
      Irvine, Irvine, CA, United States.
FAU - Veznedaroglu, Erol
AU  - Veznedaroglu E
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, PA, United 
      States.
FAU - Binning, Mandy J
AU  - Binning MJ
AD  - Department of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, PA, United 
      States.
FAU - Puri, Ajit
AU  - Puri A
AD  - Department of Radiology, University of Massachusetts Medical School, Worcester, MA, 
      United States.
FAU - Vora, Nirav A
AU  - Vora NA
AD  - Department of Radiology, Riverside Radiology and Interventional Associates, 
      Columbus, OH, United States.
FAU - Budzik, Ron F
AU  - Budzik RF
AD  - Department of Radiology, Riverside Radiology and Interventional Associates, 
      Columbus, OH, United States.
FAU - Dabus, Guilherme
AU  - Dabus G
AD  - Department of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, 
      Miami, FL, United States.
FAU - Linfante, Italo
AU  - Linfante I
AD  - Department of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, 
      Miami, FL, United States.
FAU - Janardhan, Vallabh
AU  - Janardhan V
AD  - Comprehensive Stroke Program and Neurointerventional, Texas Stroke Institute, Plano, 
      TX, United States.
FAU - Alshekhlee, Amer
AU  - Alshekhlee A
AD  - Department of Vascular and Interventional Neurology, DePaul Stroke Center-SSM 
      Neuroscience Institutes, St. Louis, MO, United States.
FAU - Abraham, Michael G
AU  - Abraham MG
AD  - Neurology and Interventional Radiology, University of Kansas Medical Center, Kansas 
      City, KS, United States.
FAU - Edgell, Randall
AU  - Edgell R
AD  - Department of Neurology, St. Louis University, St. Louis, MO, United States.
FAU - Taqi, Muhammad Asif
AU  - Taqi MA
AD  - Department of Neurology and Neurosurgery, Los Robles Hospital and Medical Center, 
      Thousand Oaks, CA, United States.
FAU - Khoury, Ramy El
AU  - Khoury RE
AD  - Department of Neurology, Tulane University, New Orleans, LA, United States.
FAU - Majjhoo, Aniel Q
AU  - Majjhoo AQ
AD  - Department of Neurology, Wayne State School of Medicine, Detroit, MI, United States.
FAU - Kabbani, Mouhammed R
AU  - Kabbani MR
AD  - Department of Neurosurgery, Gundersen Health System, La Crosse, WI, United States.
FAU - Froehler, Michael T
AU  - Froehler MT
AD  - Department of Neurology, Neurosurgery, and Radiology, Vanderbilt University Medical 
      Center, Nashville, TN, United States.
FAU - Finch, Ira
AU  - Finch I
AD  - Interventional Radiology, John Muir Health, Walnut Creek, CA, United States.
FAU - Ansari, Sameer A
AU  - Ansari SA
AD  - Department of Radiology, Neurology, and Neurological Surgery, Feinberg School of 
      Medicine, Northwestern University, Chicago, IL, United States.
FAU - Novakovic, Roberta
AU  - Novakovic R
AD  - Department of Radiology, Neurology, and Neurotherapeutics, UT Southwestern Medical 
      Center, Dallas, TX, United States.
FAU - Nguyen, Thanh N
AU  - Nguyen TN
AD  - Department of Neurology, Neurosurgery, and Radiology, Boston Medical Center, Boston, 
      MA, United States.
FAU - Zaidat, Osama O
AU  - Zaidat OO
AD  - Department of Endovascular Neurosurgery and Stroke, St. Vincent Mercy Medical 
      Center, Toledo, OH, United States.
LA  - eng
PT  - Journal Article
DEP - 20200218
TA  - Front Neurol
JT  - Frontiers in neurology
JID - 101546899
PMC - PMC7040359
OTO - NOTNLM
OT  - Ischemia—reperfusion
OT  - brain
OT  - endovascualar treatment
OT  - stroke
OT  - thrombectomy
EDAT- 2020/03/07 06:00
MHDA- 2020/03/07 06:01
CRDT- 2020/03/06 06:00
PHST- 2019/11/26 00:00 [received]
PHST- 2020/01/23 00:00 [accepted]
PHST- 2020/03/06 06:00 [entrez]
PHST- 2020/03/07 06:00 [pubmed]
PHST- 2020/03/07 06:01 [medline]
AID - 10.3389/fneur.2020.00083 [doi]
PST - epublish
SO  - Front Neurol. 2020 Feb 18;11:83. doi: 10.3389/fneur.2020.00083. eCollection 2020.

PMID- 17621010
OWN - NLM
STAT- MEDLINE
DCOM- 20070807
LR  - 20070710
IS  - 1524-4040 (Electronic)
IS  - 0148-396X (Linking)
VI  - 61
IP  - 1
DP  - 2007 Jul
TI  - Recanalization of a symptomatic extracranial internal carotid artery near occlusion 
      with proximal and distal protection: technical case report.
PG  - E174; discussion E174
AB  - OBJECTIVE: To describe a novel approach to recanalizing symptomatic extracranial 
      internal carotid artery near occlusion using proximal and distal emboli protection 
      devices. METHODS: Patients presenting with symptomatic extracranial internal carotid 
      artery near occlusion who underwent endovascular recanalization between October 2004 
      and July 2005 were included in this study. During these procedures, a 9-French 
      Concentric Balloon Guide Catheter (Concentric Medical, Mountain View, CA) was 
      advanced into the common carotid artery proximal to the site of occlusion. During 
      the prestent angioplasty of the lesion, the proximal balloon was inflated and 
      aspiration was performed. After initial angioplasty and before stent placement, a 
      distal filter protection device was placed in the distal internal carotid artery. 
      Stent placement and repeat angioplasty were performed with both protection devices 
      active. All patients were placed on dual antiplatelet therapy. RESULTS: There were 
      four patients treated with a mean age of 74 years; three of these four patients were 
      men. All patients had signs of ischemia and carotid occlusion or near occlusion on 
      noninvasive imaging. Three right internal carotid arteries were treated. All 
      patients were successfully recanalized. No procedurally related complications or 
      deaths occurred. CONCLUSION: This series demonstrates the feasibility of 
      recanalization of symptomatic carotid artery occlusion or near occlusion using 
      proximal and distal emboli protection devices. Such an approach may provide an added 
      level of safety during carotid recanalization procedures.
FAU - Edgell, Randall C
AU  - Edgell RC
AD  - Division of Neurosurgery, Neuroendovascular Section, Albany Medical Center, Albany, 
      New York 12208, USA.
FAU - Yavagal, Dileep R
AU  - Yavagal DR
FAU - Agner, Celso
AU  - Agner C
FAU - Adamo, Matthew
AU  - Adamo M
FAU - Boulos, Alan S
AU  - Boulos AS
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Neurosurgery
JT  - Neurosurgery
JID - 7802914
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Carotid Artery, Internal/*surgery
MH  - Carotid Stenosis/*surgery
MH  - Cerebral Revascularization/*methods
MH  - Humans
MH  - Male
MH  - Treatment Outcome
EDAT- 2007/07/11 09:00
MHDA- 2007/08/08 09:00
CRDT- 2007/07/11 09:00
PHST- 2007/07/11 09:00 [pubmed]
PHST- 2007/08/08 09:00 [medline]
PHST- 2007/07/11 09:00 [entrez]
AID - 00006123-200707000-00024 [pii]
AID - 10.1227/01.neu.0000279742.38178.f6 [doi]
PST - ppublish
SO  - Neurosurgery. 2007 Jul;61(1):E174; discussion E174. doi: 
      10.1227/01.neu.0000279742.38178.f6.

PMID- 23835465
OWN - NLM
STAT- MEDLINE
DCOM- 20140408
LR  - 20161125
IS  - 1532-2653 (Electronic)
IS  - 0967-5868 (Linking)
VI  - 20
IP  - 9
DP  - 2013 Sep
TI  - Tri-axial system using the Solitaire-FR and Penumbra Aspiration Microcatheter for 
      acute mechanical thrombectomy.
PG  - 1303-5
LID - S0967-5868(13)00060-X [pii]
LID - 10.1016/j.jocn.2012.10.037 [doi]
AB  - The Solitaire-FR (eV3/Covidien, Irvine, CA, USA) retrievable stent (SFR), designed 
      for mechanical thrombectomy in acute ischemic stroke, recently received Food and 
      Drug Administration approval in the USA. Clot retrieval is performed by deploying 
      the SFR through a microcatheter directly into the thrombus, to capture the clot and 
      restore perfusion. In order to perform this maneuver, a balloon guide catheter must 
      be used to apply negative suction and reverse flow within the cervical arteries, 
      thus minimizing the chance of antegrade blood flow dislodging the thrombus from the 
      stent. This technique requires at least an 8-French system that can increase the 
      risk of arterial injury at the access site particularly in older patients with 
      smaller or highly atherosclerotic peripheral arteries, and may provide inadequate 
      aspiration in the vertebrobasilar system where only one vertebral artery is accessed 
      and aspirated. The author describes a technique whereby a 6-French tri-axial system 
      is used to deliver the SFR through a Penumbra Aspiration Microcatheter (Penumbra, 
      Inc., Alameda, CA, USA) to provide intracranial aspiration in close proximity to the 
      stent.
CI  - Copyright © 2013 Elsevier Ltd. All rights reserved.
FAU - Deshaies, Eric M
AU  - Deshaies EM
AD  - Department of Neurosurgery, State University of New York Upstate Medical University, 
      750 E Adams Street, Syracuse, NY 13210, USA. deshaiee@upstate.edu
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20130705
PL  - Scotland
TA  - J Clin Neurosci
JT  - Journal of clinical neuroscience : official journal of the Neurosurgical Society of 
      Australasia
JID - 9433352
SB  - IM
MH  - Aged, 80 and over
MH  - Catheterization/instrumentation/*methods
MH  - Female
MH  - Humans
MH  - Mechanical Thrombolysis/instrumentation/*methods
MH  - Radiography
MH  - Stroke/*diagnostic imaging/*surgery
OTO - NOTNLM
OT  - Brain
OT  - Mechanical thrombectomy
OT  - Penumbra
OT  - Solitaire-FR
OT  - Stroke
EDAT- 2013/07/10 06:00
MHDA- 2014/04/09 06:00
CRDT- 2013/07/10 06:00
PHST- 2012/09/27 00:00 [received]
PHST- 2012/10/08 00:00 [accepted]
PHST- 2013/07/10 06:00 [entrez]
PHST- 2013/07/10 06:00 [pubmed]
PHST- 2014/04/09 06:00 [medline]
AID - S0967-5868(13)00060-X [pii]
AID - 10.1016/j.jocn.2012.10.037 [doi]
PST - ppublish
SO  - J Clin Neurosci. 2013 Sep;20(9):1303-5. doi: 10.1016/j.jocn.2012.10.037. Epub 2013 
      Jul 5.

PMID- 30413831
OWN - NLM
STAT- In-Process
LR  - 20200328
IS  - 1869-1447 (Electronic)
IS  - 1869-1439 (Linking)
VI  - 30
IP  - 1
DP  - 2020 Mar
TI  - Further Development of Combined Techniques Using Stent Retrievers, Aspiration 
      Catheters and BGC : The PROTECT(PLUS) Technique.
PG  - 59-65
LID - 10.1007/s00062-018-0742-9 [doi]
AB  - PURPOSE: First pass complete (mTICI 3) reperfusion must be regarded as the ultimate 
      goal in mechanical thrombectomy (MT) in patients suffering from an emergent large 
      vessel occlusion (ELVO). With this in mind a technical modification of the 
      previously published PROTECT (PRoximal balloon Occlusion TogEther with direCt 
      Thrombus aspiration during stent retriever thrombectomy) approach, the PROTECT(PLUS) 
      technique was evaluated. Under proximal flow arrest using a balloon guide catheter 
      (BGC), a stent retriever was only partially inserted into a large-bore aspiration 
      catheter. This construction was subsequently retracted as a unit into the BGC with 
      aspiration both at the aspiration catheter and at the BGC. METHODS: A case-control 
      study was performed comparing the PROTECT technique with the PROTECT(PLUS) technique 
      with respect to the technical and procedural parameters. Patients n = 165 (101 
      PROTECT, 64 PROTECT(PLUS)) with ELVO of either the terminus of the internal carotid 
      artery or the proximal middle cerebral artery were included. RESULTS: Using the 
      PROTECT(PLUS) resulted in a higher rate of first pass complete reperfusions (59.4% 
      vs. 27.7%, p < 0.001) as compared with PROTECT. The PROTECT(PLUS) also led to 
      shorter procedure times (21 min vs. 37 min, p = 0.001) and higher rates of overall 
      complete reperfusion (73.5% vs. 49.5%, p = 0.014) compared to PROTECT. CONCLUSION: 
      The PROTECT(PLUS) technique is a promising technical modification to further 
      optimize endovascular stroke treatment.
FAU - Maegerlein, Christian
AU  - Maegerlein C
AUID- ORCID: 0000-0003-4885-7671
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany. 
      christian.maegerlein@tum.de.
FAU - Berndt, Maria Teresa
AU  - Berndt MT
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
FAU - Mönch, Sebastian
AU  - Mönch S
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
FAU - Kreiser, Kornelia
AU  - Kreiser K
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
FAU - Boeckh-Behrens, Tobias
AU  - Boeckh-Behrens T
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
FAU - Lehm, Manuel
AU  - Lehm M
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
FAU - Wunderlich, Silke
AU  - Wunderlich S
AD  - Department of Neurology, Klinikum rechts der Isar, Technical University Munich, 
      Munich, Germany.
FAU - Zimmer, Claus
AU  - Zimmer C
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
FAU - Friedrich, Benjamin
AU  - Friedrich B
AD  - Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der 
      Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.
LA  - eng
PT  - Journal Article
DEP - 20181109
PL  - Germany
TA  - Clin Neuroradiol
JT  - Clinical neuroradiology
JID - 101526693
SB  - IM
OTO - NOTNLM
OT  - Balloon guide catheter
OT  - First-pass
OT  - Mechanical thrombectomy
OT  - Stroke
OT  - TICI 3
EDAT- 2018/11/11 06:00
MHDA- 2018/11/11 06:00
CRDT- 2018/11/11 06:00
PHST- 2018/10/10 00:00 [received]
PHST- 2018/10/25 00:00 [accepted]
PHST- 2018/11/11 06:00 [pubmed]
PHST- 2018/11/11 06:00 [medline]
PHST- 2018/11/11 06:00 [entrez]
AID - 10.1007/s00062-018-0742-9 [pii]
AID - 10.1007/s00062-018-0742-9 [doi]
PST - ppublish
SO  - Clin Neuroradiol. 2020 Mar;30(1):59-65. doi: 10.1007/s00062-018-0742-9. Epub 2018 
      Nov 9.

PMID- 32221623
OWN - NLM
STAT- Publisher
LR  - 20200329
IS  - 1869-1447 (Electronic)
IS  - 1869-1439 (Linking)
DP  - 2020 Mar 27
TI  - Carotid Stenting as Definitive Treatment for Free Floating Thrombus-Review of 7 
      Cases.
LID - 10.1007/s00062-020-00898-y [doi]
AB  - BACKGROUND AND PURPOSE: Free floating thrombus (FFT) is a rare condition. The 
      optimal treatment strategy is yet to be determined although medical management with 
      anticoagulation is the mainstay. This article reports experience of treating FFT 
      with carotid stenting. METHODS: A retrospective analysis of a prospectively 
      maintained database was performed to identify all patients with FFT treated with 
      carotid stenting. For each patient the demographic data, clinical presentation, 
      location of the thrombus, type of stent and use of adjunctive devices, e.g. balloon 
      guide catheters, clinical and radiological follow-up information as well as 
      complications were recorded. RESULTS: A total of 7 patients, 4 female, with mean age 
      of 55.6 ± 14.5 years were identified. The median National Institutes of Health 
      Stroke Scale (NIHSS) was 7 (range 0-13) at presentation. Free floating thrombus was 
      seen on the left in the majority of cases (n = 6, 85.7%). None of the patients had 
      intracranial large vessel occlusion. The FFT was located in the CCA in 2 cases 
      (28.6%) and the proximal ICA in the remaining 5 cases (71.4%). The Wallstent was 
      used in 5 patients and a cGuard stent used in 2 patients. In 1 patient 2 overlapping 
      stents were used but a single stent was used in the remaining patients. In 6 cases 
      a distal filter wire was used and in 2 cases a balloon guide catheter was used as 
      embolic protection. There were no intraoperative complications and no cases of 
      distal clot migration or intracranial large vessel occlusion during the procedure. 
      At last follow-up (n = 7) 6 patients were recorded as modified Rankin Scale (mRS) ≤2 
      and 1 patient was mRS 3. CONCLUSION: Free floating thrombus of the carotid arteries 
      can be managed with stenting.
FAU - Bhogal, P
AU  - Bhogal P
AD  - Department of Interventional Neuroradiology, The Royal London Hospital, Whitechapel 
      Road, E1 1BB, London, UK. bhogalweb@aol.com.
AD  - Neuroradiologische Klinik, Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany. 
      bhogalweb@aol.com.
FAU - AlMatter, M
AU  - AlMatter M
AD  - Neuroradiologische Klinik, Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany.
FAU - Aguilar Pérez, M
AU  - Aguilar Pérez M
AD  - Neuroradiologische Klinik, Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany.
FAU - Bäzner, H
AU  - Bäzner H
AD  - Neurologische Klinik, Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany.
FAU - Henkes, H
AU  - Henkes H
AD  - Neuroradiologische Klinik, Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany.
AD  - Medical Faculty, University Duisburg-Essen, Essen, Germany.
FAU - Hellstern, V
AU  - Hellstern V
AD  - Neuroradiologische Klinik, Neurozentrum, Klinikum Stuttgart, Stuttgart, Germany.
LA  - eng
PT  - Journal Article
DEP - 20200327
PL  - Germany
TA  - Clin Neuroradiol
JT  - Clinical neuroradiology
JID - 101526693
SB  - IM
OTO - NOTNLM
OT  - Atherosclerosis
OT  - Carotid
OT  - Carotid stenting
OT  - Free floating thrombus
EDAT- 2020/03/30 06:00
MHDA- 2020/03/30 06:00
CRDT- 2020/03/30 06:00
PHST- 2019/11/25 00:00 [received]
PHST- 2020/03/04 00:00 [accepted]
PHST- 2020/03/30 06:00 [entrez]
PHST- 2020/03/30 06:00 [pubmed]
PHST- 2020/03/30 06:00 [medline]
AID - 10.1007/s00062-020-00898-y [pii]
AID - 10.1007/s00062-020-00898-y [doi]
PST - aheadofprint
SO  - Clin Neuroradiol. 2020 Mar 27. doi: 10.1007/s00062-020-00898-y.

PMID- 31959631
OWN - NLM
STAT- Publisher
LR  - 20200121
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
DP  - 2020 Jan 20
TI  - Preclinical evaluation of the ANCD thrombectomy device: safety and efficacy in a 
      swine clot model.
LID - neurintsurg-2019-015548 [pii]
LID - 10.1136/neurintsurg-2019-015548 [doi]
AB  - BACKGROUND: The Advanced Thrombectomy System (ANCD) provides a new funnel component 
      designed to reduce clot fragmentation and facilitate retrieval in patients with 
      stroke by locally restricting flow, allowing distal aspiration in combination with a 
      stent retriever (SR). OBJECTIVE: To evaluate the preclinical efficacy and safety of 
      the ANCD in a swine clot model. METHODS: Soft and firm clots were implanted in the 
      lingual and cervical arteries of 11 swine to obtain Thrombolysis in Cerebral 
      Infarction (TICI) 0 blood flow. Mechanical thrombectomy was performed with either a 
      balloon guide catheter+Solitaire 2 stent retriever (BGC+SR, n=13) or ANCD+SR (n=13). 
      TICI flow was evaluated and successful revascularization was defined as TICI 3 
      (normal perfusion). To characterize safety, a total of 3 passes were performed in 
      each vessel independent of recanalization. Tissues were explanted for 
      histopathological analysis after 3 and 30 days, respectively. RESULTS: First pass 
      reperfusion rates were ANCD+SR: 69% and BGC+SR: 46%. Reperfusion increased after the 
      third pass in both groups (ANCD+SR: 100%, vs BGC+SR: 77%). Recanalization was 
      achieved after an average of 1.4 and 1.9 passes in ANCD+SR and BGC+SR (p=0.095), 
      respectively. Vessel injury was comparable in both groups; endothelial loss at 3 
      days was the most common injury seen (ANCD+SR: 1.78±1.22; BGC+SR: 2.03±1.20; 
      p=0.73), while other histopathological markers were absent or minimal. Tissues 
      downstream from targeted vessels also showed absence or minimal lesions across both 
      groups. CONCLUSIONS: Results in a swine clot model support the high efficacy of the 
      ANCD+SR without causing clinically significant vessel injury potentially related to 
      the new funnel component.
CI  - © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Sanchez, Sonia
AU  - Sanchez S
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Bailey, Lynn
AU  - Bailey L
AD  - CBSET Inc, Lexington, Massachusetts, USA.
FAU - Ducore, Rebecca
AU  - Ducore R
AD  - CBSET Inc, Lexington, Massachusetts, USA.
FAU - Andersson, Tommy
AU  - Andersson T
AD  - Departments of Radiology and Neurology, AZ Groeninge, Kortrijk, Belgium.
AD  - Departments of Neuroradiology, Karolinska University Hospital and Clinical 
      Neuroscience, Karolinska University Hospital; Karolinska Institutet, Stockholm, 
      Sweden.
FAU - Nogueira, Raul
AU  - Nogueira R
AD  - Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
FAU - Cognard, Christophe
AU  - Cognard C
AD  - Department of Diagnostic and Therapeutic Neuroradiology, Hôpital Purpan, Toulouse, 
      France.
FAU - Ribo, Marc
AU  - Ribo M
AD  - Stroke Unit, Neurology, Hospital Vall d'Hebron, Barcelona, Spain 
      marcriboj@hotmail.com.
AD  - Universitat Autònoma de Barcelona.
FAU - Villanova, Helena
AU  - Villanova H
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
AD  - Escola Tècnica Superior de Enginyeria Industrial de Barcelona (ETSEIB), Universidad 
      Politécnica de Cataluña, Barcelona, Spain.
FAU - Rios, Anna
AU  - Rios A
AD  - R&D, Anaconda Biomed, Barcelona, St Cugat del Valles, Spain.
FAU - Galve, Iñaki
AU  - Galve I
AD  - Anaconda Biomed, Barcelona, Spain.
LA  - eng
PT  - Journal Article
DEP - 20200120
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
SB  - IM
OTO - NOTNLM
OT  - stroke
OT  - thrombectomy
OT  - vessel wall
COIS- Competing interests: SS, HV, AR, and IG are employees of Anaconda Biomed. LB and RD 
      are employees of CBSET, a not-for-profit research organization, which received 
      research funding from Anaconda Biomed for the reported work. MR is a shareholder in 
      Anaconda Biomed, consultant for Cerenovus, Medtronic, Stryker, Apta Targets, and 
      Vesalio. TA is clinical consultant for Anaconda, Ablynx, Amnis Therapeutics, 
      Cerenovus/Neuravi, Medtronic, and Rapid Medical. RN: Stryker Neurovascular (DAWN 
      trial principal investigator- no compensation, TREVO Registry Steering Committee – 
      no compensation, Trevo-2 trial principal investigator- modest; consultant - 
      significant); Medtronic (SWIFT Trial Steering Committee - modest; SWIFT-Prime Trial 
      Steering Committee – no compensation; STAR Trial Angiographic Core Lab - 
      significant); Penumbra (3D Separator Trial Executive Committee – no compensation); 
      Cerenovus/ Neuravi (ENDOLOW Trial Principal Investigator, EXCELLENT Registry 
      Principal Investigator, ARISE-2 trial Steering Committee – no compensation, 
      Physician Advisory Board, modest); Phenox (PROST Trial Principal Investigator, 
      Physician Advisory Board, modest); Anaconda (Physician Advisory Board, modest); 
      Genentech (Physician Advisory Board – modest); Biogen (CHARM Trial Steering 
      Committee; Physician Advisory Board – modest). Pharmaceuticals (Physician Advisory 
      Board – modest); Allm Inc. (Physician Advisory Board – no compensation); IschemaView 
      (Speaker, modest); Brainomix (Physician Advisory Board, stock options); Sensome 
      (Research Device Use – no compensation); Viz-AI (Physician Advisory Board, stock 
      options); Philips (Research Software Use – no compensation, Speaker - modest); 
      Corindus Vascular Robotics (Physician Advisory Board, stock options); Vesalio 
      (Physician Advisory Board, stock options); Ceretrieve (Physician Advisory Board, 
      stock options); Astrocyte (Physician Advisory Board, stock options). CC is 
      consultant for Sequent Medical, MicroVention, Stryker and Codman.
EDAT- 2020/01/22 06:00
MHDA- 2020/01/22 06:00
CRDT- 2020/01/22 06:00
PHST- 2019/10/26 00:00 [received]
PHST- 2019/12/14 00:00 [revised]
PHST- 2019/12/22 00:00 [accepted]
PHST- 2020/01/22 06:00 [entrez]
PHST- 2020/01/22 06:00 [pubmed]
PHST- 2020/01/22 06:00 [medline]
AID - neurintsurg-2019-015548 [pii]
AID - 10.1136/neurintsurg-2019-015548 [doi]
PST - aheadofprint
SO  - J Neurointerv Surg. 2020 Jan 20:neurintsurg-2019-015548. doi: 
      10.1136/neurintsurg-2019-015548.

PMID- 32054612
OWN - NLM
STAT- In-Data-Review
LR  - 20200320
IS  - 1936-959X (Electronic)
IS  - 0195-6108 (Print)
IS  - 0195-6108 (Linking)
VI  - 41
IP  - 3
DP  - 2020 Mar
TI  - Comparison of Aspiration versus Stent Retriever Thrombectomy as the Preferred 
      Strategy for Patients with Acute Terminal Internal Carotid Artery Occlusion: A 
      Propensity Score Matching Analysis.
PG  - 469-476
LID - 10.3174/ajnr.A6414 [doi]
AB  - BACKGROUND AND PURPOSE: There is no consensus on endovascular treatment for terminal 
      ICA. The purpose of this study was to evaluate the comparative safety and efficacy 
      of preferred aspiration thrombectomy and stent retriever thrombectomy for 
      revascularization in patients with isolated terminal ICA occlusion. MATERIALS AND 
      METHODS: We conducted a retrospective analysis of patients with terminal ICA 
      occlusion treated with aspiration thrombectomy or stent retriever thrombectomy in 
      our center, from September 2013 to November 2018. To minimize the case bias, 
      propensity score matching was performed. The primary outcomes were successful 
      reperfusion defined by expanded TICI grades 2b-3 at the end of all endovascular 
      procedures and puncture-to-reperfusion time. RESULTS: A total of 109 consecutive 
      patients with terminal ICA occlusion were divided into the aspiration thrombectomy 
      group (40 patients) and the stent retriever thrombectomy group (69 patients), and 30 
      patients were included in each group after propensity score matching. The proportion 
      of complete reperfusion was significantly higher in the aspiration thrombectomy 
      group (OR 4.75 [95% CI, 1.10-1.38]; P = .002). The median puncture-to-reperfusion 
      time in the aspiration thrombectomy group was shorter than that in the stent 
      retriever thrombectomy group (38  versus 69 minutes; P = .001). Fewer intracerebral 
      hemorrhage events were recorded in the aspiration thrombectomy group (OR 0.29 [95% 
      CI, 0.09-0.90]; P = .028). No significant differences were observed for good 
      outcomes (OR 1.92 [95% CI, 0.86-4.25]) and mortality (OR 0.84 [95% CI, 0.29-2.44]) 
      at 90 days. CONCLUSIONS: For the treatment of terminal ICA occlusion, aspiration 
      thrombectomy was technically superior to stent retriever thrombectomy in the absence 
      of a balloon guide catheter in achieving successful reperfusion with shorter 
      puncture-to-reperfusion time and procedure-related adverse events.
CI  - © 2020 by American Journal of Neuroradiology.
FAU - Xing, P F
AU  - Xing PF
AUID- ORCID: 0000-0002-2663-1092
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Yang, P F
AU  - Yang PF
AUID- ORCID: 0000-0002-6154-3602
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Li, Z F
AU  - Li ZF
AUID- ORCID: 0000-0002-9332-3786
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Zhang, L
AU  - Zhang L
AUID- ORCID: 0000-0001-5559-6292
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Shen, H J
AU  - Shen HJ
AUID- ORCID: 0000-0002-4439-9506
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Zhang, Y X
AU  - Zhang YX
AUID- ORCID: 0000-0003-1525-5893
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Zhang, Y W
AU  - Zhang YW
AUID- ORCID: 0000-0001-9958-3098
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China.
FAU - Liu, J M
AU  - Liu JM
AUID- ORCID: 0000-0003-2768-7298
AD  - From the Department of Stroke Center, Changhai Hospital, Second Military Medical 
      University, Shanghai, China. Liu118@vip.163.com.
LA  - eng
PT  - Journal Article
DEP - 20200213
TA  - AJNR Am J Neuroradiol
JT  - AJNR. American journal of neuroradiology
JID - 8003708
SB  - IM
PMC - PMC7077898
EDAT- 2020/02/15 06:00
MHDA- 2020/02/15 06:00
PMCR- 2021/03/01
CRDT- 2020/02/15 06:00
PHST- 2019/10/29 00:00 [received]
PHST- 2019/12/23 00:00 [accepted]
PHST- 2021/03/01 00:00 [pmc-release]
PHST- 2020/02/15 06:00 [pubmed]
PHST- 2020/02/15 06:00 [medline]
PHST- 2020/02/15 06:00 [entrez]
AID - ajnr.A6414 [pii]
AID - 19-01120 [pii]
AID - 10.3174/ajnr.A6414 [doi]
PST - ppublish
SO  - AJNR Am J Neuroradiol. 2020 Mar;41(3):469-476. doi: 10.3174/ajnr.A6414. Epub 2020 
      Feb 13.
